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\n\u5c1a\u3001\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u540c\u58eb\u306e\u76f8\u4e92\u4f5c\u7528\u306b\u3064\u3044\u3066\u306f\u3001\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u3067\u8abf\u67fb\u3057\u305f\u304c\u6709\u5bb3\u4e8b\u4f8b\u306f\u5831\u544a\u3055\u308c\u3066\u304a\u3089\u305a\u3001\u554f\u984c\u306f\u306a\u3044\u3068\u5224\u65ad\u3057\u305f\u3002<\/p>\n

\u6a5f\u80fd\u6027\u306b\u95a2\u3059\u308b\u57fa\u672c\u60c5\u5831<\/h2>\n

\u6a5f\u80fd\u6027\u306e\u8a55\u4fa1\u65b9\u6cd5<\/h3>\n

\u25a0\u6700\u7d42\u88fd\u54c1\u3067\u306f\u306a\u304f\u3001\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u306b\u95a2\u3059\u308b\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\u3067\u3001\u6a5f\u80fd\u6027\u3092\u8a55\u4fa1\u3057\u3066\u3044\u308b\u3002<\/p>\n

\u5f53\u8a72\u88fd\u54c1\u306e\u6a5f\u80fd\u6027\u306b\u95a2\u3059\u308b\u5c4a\u51fa\u8005\u306e\u8a55\u4fa1<\/h3>\n

\u3010N-\u30a2\u30bb\u30c1\u30eb\u30b0\u30eb\u30b3\u30b5\u30df\u30f3\u3011
\n\u3010\u6a19\u984c\u3011
\n\u6700\u7d42\u88fd\u54c1\u300c\u3072\u3056\u95a2\u7bc0\u306e\u304a\u60a9\u307f\u6539\u5584\u30b5\u30dd\u30fc\u30c8\u300d\u306b\u542b\u6709\u3059\u308b\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206N-\u30a2\u30bb\u30c1\u30eb\u30b0\u30eb\u30b3\u30b5\u30df\u30f3\u306b\u3088\u308b\u819d\u95a2\u7bc0\u6a5f\u80fd\u306e\u6539\u5584\u306b\u95a2\u3059\u308b\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc<\/p>\n

\u3010\u76ee\u7684\u3011
\nN-\u30a2\u30bb\u30c1\u30eb\u30b0\u30eb\u30b3\u30b5\u30df\u30f3\u306e\u6442\u53d6\u304c\u819d\u95a2\u7bc0\u6a5f\u80fd\u306e\u6539\u5584\u306b\u53ca\u307c\u3059\u5f71\u97ff\u3092\u8a55\u4fa1\u3059\u308b<\/p>\n

\u3010\u80cc\u666f\u3011
\nN-\u30a2\u30bb\u30c1\u30eb\u30b0\u30eb\u30b3\u30b5\u30df\u30f3\u306f\u30d2\u30a2\u30eb\u30ed\u30f3\u9178\u7b49\u306e\u30b0\u30ea\u30b3\u30b5\u30df\u30ce\u30b0\u30ea\u30ab\u30f3\u306e\u69cb\u6210\u6210\u5206\u3067\u3042\u308a\u3001\u95a2\u7bc0\u306e\u69cb\u9020\u7684\u306a\u30de\u30c8\u30ea\u30c3\u30af\u30b9\u306e\u4e3b\u306a\u69cb\u6210\u8981\u7d20\u3068\u306a\u308b\u3002\u7d30\u80de\u3092\u7528\u3044\u305f\uff08in vitro\uff09\u7814\u7a76\u3067\u306fN-\u30a2\u30bb\u30c1\u30eb\u30b0\u30eb\u30b3\u30b5\u30df\u30f3\u306f\u30b0\u30ea\u30b3\u30b5\u30df\u30ce\u30b0\u30ea\u30ab\u30f3\u306e\u7523\u751f\u3001\u30b3\u30e9\u30fc\u30b2\u30f3\u304a\u3088\u3073\u30d2\u30a2\u30eb\u30ed\u30f3\u9178\u306e\u5897\u52a0\u3001\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u7523\u751f\u6291\u5236\u4f5c\u7528\u3092\u6709\u3059\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3002\u307e\u305f\u3001\u30d2\u30c8\u8a66\u9a13\u306b\u304a\u3044\u3066\u306f\u5909\u5f62\u6027\u819d\u95a2\u7bc0\u75c7\u306e\u60a3\u8005\u304cN-\u30a2\u30bb\u30c1\u30eb\u30b0\u30eb\u30b3\u30b5\u30df\u30f3500\u338e\/\u65e5\u307e\u305f\u306f1000mg\/\u65e5\u5165\u308a\u306e\u30df\u30eb\u30af\u30928\u9031\u9593\u6442\u53d6\u3057\u305f\u7d50\u679c\u3001\u819d\u75be\u60a3\u6cbb\u7642\u5224\u5b9a\u57fa\u6e96\u306e\u6210\u7e3e\u304c\u5411\u4e0a\u3057\u3001\u75bc\u75db\u30fb\u6b69\u884c\u80fd\u3068\u75bc\u75db\u30fb\u968e\u6bb5\u6607\u964d\u80fd\u306e2\u9805\u76ee\u306b\u304a\u3044\u3066\u6709\u610f\u306a\u6539\u5584\u304c\u8a8d\u3081\u3089\u308c\u305f\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3002\u3053\u308c\u3088\u308aN-\u30a2\u30bb\u30c1\u30eb\u30b0\u30eb\u30b3\u30b5\u30df\u30f3\u306f\u30d2\u30c8\u306e\u819d\u95a2\u7bc0\u6a5f\u80fd\u306e\u6539\u5584\u306b\u5f79\u7acb\u3064\u53ef\u80fd\u6027\u304c\u8003\u3048\u3089\u308c\u308b\u3002<\/p>\n

\u3010\u30ec\u30d3\u30e5\u30fc\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u306e\u7279\u6027\u3011
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\n\u8ad6\u6587\u306e\u691c\u7d22\u65e5\uff1a2020\u5e7411\u670830\u65e5
\n\u691c\u7d22\u5bfe\u8c61\u671f\u9593\uff1a\u691c\u7d22\u65e5\u307e\u3067
\n\u5bfe\u8c61\u96c6\u56e3\u306e\u7279\u6027\uff1a\u5065\u5e38\u6210\u4eba
\n\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\uff1aPubMed\u3001JDream\u2162
\n\u7814\u7a76\u30c7\u30b6\u30a4\u30f3\uff1a\u30d7\u30e9\u30bb\u30dc\u5bfe\u7167\u30e9\u30f3\u30c0\u30e0\u5316\u4e8c\u91cd\u76f2\u691c\u4e26\u884c\u7fa4\u9593\u6bd4\u8f03\u8a66\u9a13
\n\u5229\u76ca\u76f8\u53cd\u60c5\u5831\uff1a\u30d7\u30ed\u30c6\u30a4\u30f3\u30b1\u30df\u30ab\u30eb\u682a\u5f0f\u4f1a\u793e\u3067\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\u3092\u5b9f\u65bd\u3002<\/p>\n

\u3010\u4e3b\u306a\u7d50\u679c\u3011
\n\u6700\u7d42\u7684\u306b1\u5831\u306e\u6587\u732e\u304c\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\u306e\u5bfe\u8c61\u3068\u3057\u3066\u63a1\u629e\u3055\u308c\u305f\u3002\u5bfe\u8c61\u3068\u306a\u3063\u305f\u6587\u732e\u306f\u819d\u306b\u9055\u548c\u611f\u304c\u3042\u308b\u8005\u3001\u307e\u305f\u306fKL\u5206\u985e\u306b\u304a\u3044\u3066\u5065\u5e38\u8005\u306b\u3042\u305f\u308bKL\u50240\u307e\u305f\u306f\u2160\u3068\u8a3a\u65ad\u3055\u308c\u305f\u4eba\u3092\u5bfe\u8c61\u3068\u3057\u305f\u30d7\u30e9\u30bb\u30dc\u5bfe\u7167\u30e9\u30f3\u30c0\u30e0\u5316\u4e8c\u91cd\u76f2\u691c\u4e26\u884c\u7fa4\u9593\u6bd4\u8f03\u8a66\u9a13\u3067\u3042\u3063\u305f\u3002\u88ab\u9a13\u8005\u304c\u8a66\u9a13\u98df\u54c1\uff08N-\u30a2\u30bb\u30c1\u30eb\u30b0\u30eb\u30b3\u30b5\u30df\u30f3300mg\/\u65e5\u5165\u308a\u30cf\u30fc\u30c9\u30ab\u30d7\u30bb\u30eb\uff09\u307e\u305f\u306f\u30d7\u30e9\u30bb\u30dc\u54c1\u309212\u9031\u9593\u7d4c\u53e3\u6442\u53d6\u3057\u305f\u7d50\u679c\u3001\u8a66\u9a13\u98df\u54c1\u6442\u53d6\u7fa4\u306b\u304a\u3044\u3066JOA\u8a55\u4fa1\uff08\u75bc\u75db\u30fb\u6b69\u884c\u80fd\u529b\u3068\u75bc\u75db\u30fb\u968e\u6bb5\u6607\u964d\u80fd\u529b\u306e2\u9805\u76ee\uff09\u306e\u6709\u610f\u306a\u6539\u5584\u304c\u8a8d\u3081\u3089\u308c\u305f\u3002\u3053\u308c\u3088\u308aN-\u30a2\u30bb\u30c1\u30eb\u30b0\u30eb\u30b3\u30b5\u30df\u30f3\u3092300mg\/\u65e5\u4ee5\u4e0a\u7d99\u7d9a\u6442\u53d6\u3059\u308b\u3053\u3068\u306f\u30b0\u30ea\u30b3\u30b5\u30df\u30ce\u30b0\u30ea\u30ab\u30f3\u7523\u751f\u3001\u30b3\u30e9\u30fc\u30b2\u30f3\u304a\u3088\u3073\u30d2\u30a2\u30eb\u30ed\u30f3\u9178\u306e\u5897\u52a0\u3001\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u7523\u751f\u6291\u5236\u7b49\u306e\u4f5c\u7528\u3092\u901a\u3058\u3066\u30d2\u30c8\u306e\u819d\u95a2\u7bc0\u6a5f\u80fd\u306e\u6539\u5584\u306b\u5f79\u7acb\u3064\u3068\u8003\u3048\u3089\u308c\u305f\u3002<\/p>\n

\u3010\u79d1\u5b66\u7684\u6839\u62e0\u306e\u8cea\u3011
\n\u672c\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\u3067\u9078\u629e\u3055\u308c\u305f\u8ad6\u6587\u306e\u5bfe\u8c61\u8005\u3001\u6761\u4ef6\u3001\u8a55\u4fa1\u9805\u76ee\u306f\u30ec\u30d3\u30e5\u30fc\u306e\u76ee\u7684\u306b\u8a2d\u5b9a\u3057\u305f\u5bfe\u8c61\u8005\u3001\u6761\u4ef6\u3001\u8a55\u4fa1\u9805\u76ee\u3068\u4e00\u81f4\u3057\u305f\u3002\u4e00\u65b9\u3001\u672c\u5546\u54c1\u306e\u6442\u53d6\u76ee\u5b89\u91cf\u306fN-\u30a2\u30bb\u30c1\u30eb\u30b0\u30eb\u30b3\u30b5\u30df\u30f3500mg\/\u65e5\u3067\u30ec\u30d3\u30e5\u30fc\u306e\u7814\u7a76\u3088\u308a\u3082200mg\u591a\u3044\u3002\u819d\u95a2\u7bc0\u306b\u9055\u548c\u611f\u30fb\u75db\u307f\u304c\u3042\u308b\u5065\u5e38\u8005\u3092\u5bfe\u8c61\u3068\u3057\u305f\u81e8\u5e8a\u8a66\u9a13\u3067\u306fN-\u30a2\u30bb\u30c1\u30eb\u30b0\u30eb\u30b3\u30b5\u30df\u30f3\u3092500mg\u300112\u9031\u9593\u6442\u53d6\u3057\u305f\u969b\u3001\u819d\u306b\u95a2\u308f\u308b\u9805\u76ee\u3067\u6709\u610f\u306a\u6539\u5584\u304c\u8a8d\u3081\u3089\u308c\u3066\u3044\u308b\u3053\u3068\u3001\u5909\u5f62\u6027\u819d\u95a2\u7bc0\u75c7\u88ab\u9a13\u8005\u3092\u542b\u3080\u30d2\u30c8\u8a66\u9a13\u306b\u304a\u3044\u3066\u306fN-\u30a2\u30bb\u30c1\u30eb\u30b0\u30eb\u30b3\u30b5\u30df\u30f31000mg\/\u65e5\u6442\u53d6\u3057\u305f\u969b\u306b\u30d7\u30e9\u30bb\u30dc\u306b\u6bd4\u3079\u3066\u6709\u610f\u306a\u6539\u5584\u304c\u8a8d\u3081\u3089\u308c\u3066\u3044\u308b\u3053\u3068\u304b\u3089\u3001\u672c\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\u3067\u306e\u6442\u53d6\u91cf\u3088\u308a\u591a\u3044\u91cf\u3067\u3042\u3063\u3066\u3082\u540c\u7b49\u306e\u6539\u5584\u52b9\u679c\u304c\u5f97\u3089\u308c\u308b\u3068\u63a8\u5bdf\u3059\u308b\u3002\u3057\u304b\u3057\u3001\u672c\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\u3067\u63a1\u629e\u3055\u308c\u305f\u8ad6\u6587\u6570\u304c1\u5831\u3068\u5c11\u306a\u3044\u3053\u3068\u304b\u3089\u51fa\u7248\u30d0\u30a4\u30a2\u30b9\u306e\u53ef\u80fd\u6027\u3092\u5426\u5b9a\u3067\u304d\u306a\u3044\u3068\u5224\u65ad\u3057\u305f\u3002\u4eca\u5f8c\u3082\u5b9a\u671f\u7684\u306b\u60c5\u5831\u53ce\u96c6\u3092\u884c\u3044\u3001\u691c\u8a3c\u3057\u3066\u3044\u304f\u5fc5\u8981\u304c\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u3002<\/p>\n

\u3010\u30b5\u30b1\u9f3b\u8edf\u9aa8\u7531\u6765\u30d7\u30ed\u30c6\u30aa\u30b0\u30ea\u30ab\u30f3\u3011
\n\u3010\u6a19\u984c\u3011
\n\u30b5\u30b1\u9f3b\u8edf\u9aa8\u7531\u6765\u30d7\u30ed\u30c6\u30aa\u30b0\u30ea\u30ab\u30f3\u306b\u3088\u308b\u95a2\u7bc0\u8edf\u9aa8\u306e\u4fdd\u8b77\u3001\u819d\u95a2\u7bc0\u306e\u53ef\u52d5\u6027\u3092\u30b5\u30dd\u30fc\u30c8\u3059\u308b\u6a5f\u80fd\u6027\u306b\u95a2\u3059\u308b\u7814\u7a76\u30ec\u30d3\u30e5\u30fc<\/p>\n

\u3010\u76ee\u7684\u3011
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