{"id":18336,"date":"2022-01-28T07:10:56","date_gmt":"2022-01-27T22:10:56","guid":{"rendered":"https:\/\/yakujihou-marketing.net\/database\/?p=18336"},"modified":"2022-03-07T20:04:43","modified_gmt":"2022-03-07T11:04:43","slug":"g1059","status":"publish","type":"post","link":"https:\/\/yakujihou-marketing.net\/database\/g1059\/","title":{"rendered":"\uff30\uff35\uff32\uff25 \uff33\uff2b\uff29\uff2e\uff0b\uff08\u30d4\u30e5\u30a2\u30b9\u30ad\u30f3\u30d7\u30e9\u30b9\uff09(G1059)"},"content":{"rendered":"\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
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\u4e00\u65e5\u5f53\u305f\u308a\u306e\u6442\u53d6\u76ee\u5b89\u91cf<\/td>\n2\u7c92<\/td>\n<\/tr>\n
\u4e00\u65e5\u5f53\u305f\u308a\u306e\u6442\u53d6\u76ee\u5b89\u91cf\u5f53\u305f\u308a\u306e\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u306e\u542b\u6709\u91cf<\/td>\n\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u540d\uff1a\u30d9\u30fc\u30bf\u30ab\u30ed\u30c6\u30f3\u3001GABA\u3001\u3053\u3093\u306b\u3083\u304f\u7531\u6765\u30b0\u30eb\u30b3\u30b7\u30eb\u30bb\u30e9\u30df\u30c9
\n\u542b\u6709\u91cf\uff1a24mg\u3001100 mg\u3001600\u03bcg\u3001<\/td>\n<\/tr>\n
\u4fdd\u5b58\u306e\u65b9\u6cd5<\/td>\n\u76f4\u5c04\u65e5\u5149\u3001\u9ad8\u6e29\u591a\u6e7f\u3092\u907f\u3051\u3001\u6dbc\u3057\u3044\u3068\u3053\u308d\u306b\u4fdd\u5b58\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/td>\n<\/tr>\n
\u6442\u53d6\u306e\u65b9\u6cd5<\/td>\n1\u65e52\u7c92\u3092\u76ee\u5b89\u306b\u3001\u565b\u307e\u305a\u306b\u6c34\u307e\u305f\u306f\u304a\u6e6f\u3068\u3068\u3082\u306b\u304a\u53ec\u3057\u4e0a\u304c\u308a\u304f\u3060\u3055\u3044\u3002<\/td>\n<\/tr>\n
\u6442\u53d6\u3092\u3059\u308b\u4e0a\u3067\u306e\u6ce8\u610f\u4e8b\u9805<\/td>\n\u25cf\u672c\u54c1\u306f\u3001\u591a\u91cf\u6442\u53d6\u306b\u3088\u308a\u75be\u75c5\u304c\u6cbb\u7652\u3057\u305f\u308a\u3001\u3088\u308a\u5065\u5eb7\u304c\u5897\u9032\u3059\u308b\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002
\n\u25cf1\u65e5\u306e\u6442\u53d6\u76ee\u5b89\u91cf\u3092\u5b88\u3063\u3066\u304f\u3060\u3055\u3044\u3002
\n\u25cf\u964d\u5727\u85ac\u3092\u670d\u7528\u3057\u3066\u3044\u308b\u65b9\u306f\u533b\u5e2b\u3001\u85ac\u5264\u5e2b\u306b\u76f8\u8ac7\u3057\u3066\u304f\u3060\u3055\u3044\u3002
\n\u25cf\u533b\u85ac\u54c1\u3067\u3042\u308b\u30b7\u30f3\u30d0\u30b9\u30bf\u30c1\u30f3\u3068\u30ca\u30a4\u30a2\u30b7\u30f3\u3092\u4f75\u7528\u3055\u308c\u3066\u3044\u308b\u65b9\u306f\u672c\u54c1\u306e\u6442\u53d6\u3092\u907f\u3051\u3066\u304f\u3060\u3055\u3044\u3002<\/td>\n<\/tr>\n
\u8abf\u7406\u53c8\u306f\u4fdd\u5b58\u306e\u65b9\u6cd5\u306b\u95a2\u3057\u7279\u306b\u6ce8\u610f\u3092\u5fc5\u8981\u3068\u3059\u308b\u3082\u306e\u306b\u3042\u3063\u3066\u306f\u5f53\u8a72\u6ce8\u610f\u4e8b\u9805<\/td>\n\u7121<\/td>\n<\/tr>\n
\u6d88\u8cbb\u8005\u5e81URL<\/td>\nhttps:\/\/www.fld.caa.go.jp\/caaks\/cssc02\/?recordSeq=42201270080100<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u5b89\u5168\u6027\u306b\u95a2\u3059\u308b\u57fa\u672c\u60c5\u5831<\/h2>\n

\u5b89\u5168\u6027\u306e\u8a55\u4fa1\u65b9\u6cd5<\/h3>\n

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\u672c\u5c4a\u51fa\u5546\u54c1\u306f\u30d9\u30fc\u30bf\u30ab\u30ed\u30c6\u30f324 mg\u3001GABA100 mg\u3001\u3053\u3093\u306b\u3083\u304f\u7531\u6765\u30b0\u30eb\u30b3\u30b7\u30eb\u30bb\u30e9\u30df\u30c9 600\u03bcg\u3001\u3092\u542b\u3080\u98df\u54c1\u3067\u3042\u308b\u3002<\/p>\n

\u25cf\u30d9\u30fc\u30bf\u30ab\u30ed\u30c6\u30f3
\n\u65e2\u5b58\u60c5\u5831\u306e\u5b89\u5168\u6027\u8a66\u9a13\u306e\u8a55\u4fa1\u3067\u306f\u300120\uff5e25\u6b73\u306e\u5065\u5eb7\u306a\u975e\u55ab\u7159\u7537\u5b5030\u4eba (\u65e5\u672c) \u3092\u5bfe\u8c61\u3068\u3057\u305f\u30d7\u30e9\u30bb\u30dc\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u6bd4\u8f03\u8a66\u9a13\u306b\u304a\u3044\u3066\u3001all-trans \u30d9\u30fc\u30bf-\u30ab\u30ed\u30c6\u30f360 mg\/\u65e5\u307e\u305f\u306f9-cis\u578b\u3092\u542b\u3080\u30d9\u30fc\u30bf\u30ab\u30ed\u30c6\u30f3 60 mg\/\u65e5\u309244\u9031\u9593\u9023\u7d9a\u6295\u4e0e\u3057\u305f\u3068\u3053\u308d\u3001\u8840\u4e2d\u306e\u30d9\u30fc\u30bf\u30ab\u30ed\u30c6\u30f3\u6fc3\u5ea6\u30fb\u514d\u75ab\u5b66\u7684\u691c\u67fb\u30fb\u8840\u6db2\u30fb\u809d\u6a5f\u80fd\u30fb\u814e\u6a5f\u80fd\u306b\u7570\u5e38\u306f\u898b\u3089\u308c\u306a\u304b\u3063\u305f\u3002\u55ab\u7159\u8005\u306b\u6295\u4e0e\u3059\u308b\u5834\u5408\u3001\u5371\u967a\u6027\u304c\u793a\u5506\u3055\u308c\u300120 mg\u30925\uff5e8\u5e74\u6bce\u65e5\u6442\u53d6\u3059\u308b\u3068\u80ba\u304c\u3093\u304a\u3088\u3073\u524d\u7acb\u817a\u304c\u3093\u3001\u8133\u51fa\u8840\u3001\u5fc3\u81d3\u8840\u7ba1\u75c5\u306e\u30ea\u30b9\u30af\u3092\u4e0a\u6607\u3055\u305b\u3001\u6b7b\u4ea1\u7387\u3092\u4e0a\u3052\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002
\n\u4ee5\u4e0a\u306e\u3053\u3068\u304b\u3089\u5065\u5e38\u4eba\u306b\u304a\u3044\u3066\u306f24mg\/\u65e5\u306e\u30d9\u30fc\u30bf\u30ab\u30ed\u30c6\u30f3\u6442\u53d6\u306f\u5b89\u5168\u3067\u3042\u308b\u3068\u5224\u65ad\u3067\u304d\u308b\u3002<\/p>\n

\u25cfGABA
\n\u65e2\u5b58\u60c5\u5831\u306e\u5b89\u5168\u6027\u8a66\u9a13\u306e\u8a55\u4fa1\u3067\u306f\u3001GABA\u306e\u98df\u54c1\u3068\u3057\u3066\u306e\u5b89\u5168\u6027\u306b\u95a2\u3059\u308b\u7814\u7a76\u5831\u544a\u3092\u691c\u7d22\u3057\u305f\u3068\u3053\u308d\u300124\u5831\u3042\u3063\u305f\u300211.5\uff5e1,000 mg\u306eGABA\u30922\u9031\u9593\uff5e6\u304b\u6708\u9593\u6442\u53d6\u3057\u305f\u5834\u5408\u306b\u3001\u8efd\u5ea6\u306e\u81ea\u899a\u75c7\u72b6\u5909\u5316\u3092\u8a34\u3048\u308b\u4e8b\u4f8b\uff08\u4e0b\u75e2\u3001\u8179\u75db\u3001\u304a\u8179\u304c\u5f35\u308b\u3001\u98df\u6b32\u4e0d\u632f\u306a\u3069\uff09\u306f\u3042\u308b\u3082\u306e\u306e\u3001\u5b89\u5168\u6027\u306b\u554f\u984c\u306f\u306a\u304b\u3063\u305f\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3002\u307e\u305f\u3001\u672c\u5c4a\u51fa\u54c1\u306b\u542b\u307e\u308c\u308b\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u91cf\u306e5\u500d\u91cf\u4ee5\u4e0a\u306eGABA 1,000 mg\u30924\u9031\u9593\u6442\u53d6\u3057\u305f\u8a66\u9a13\u306b\u304a\u3044\u3066\u3082\u5b89\u5168\u6027\u306b\u554f\u984c\u306e\u306a\u3044\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b
\n\u672c\u5c4a\u51fa\u5546\u54c1\u306e1\u65e5\u5f53\u305f\u308a\u306e\u6442\u53d6\u76ee\u5b89\u91cf\uff08GABA100 mg\uff09\u306b\u304a\u3044\u3066\u306f\u3001\u5b89\u5168\u6027\u306b\u306f\u554f\u984c\u306a\u3044\u3068\u8003\u3048\u3089\u308c\u308b\u3002\u3057\u304b\u3057\u306a\u304c\u3089\u964d\u5727\u5264\u306a\u3069\u306e\u533b\u85ac\u54c1\u3092\u4f75\u7528\u3059\u308b\u3068\u8840\u5727\u3092\u4e0b\u3052\u3059\u304e\u3066\u3057\u307e\u3046\u53ef\u80fd\u6027\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u306e\u3067\u3001\u6442\u53d6\u3092\u3059\u308b\u4e0a\u3067\u306e\u6ce8\u610f\u4e8b\u9805\u306b\u3001\u964d\u5727\u5264\u7b49\u306e\u533b\u85ac\u54c1\u670d\u7528\u8005\u306f\u672c\u5c4a\u51fa\u54c1\u306e\u5229\u7528\u306b\u3064\u3044\u3066\u533b\u5e2b\u3001\u85ac\u5264\u5e2b\u306b\u76f8\u8ac7\u3059\u3079\u304d\u3067\u3042\u308b\u65e8\u3092\u8868\u793a\u3057\u3066\u3044\u308b\u3002<\/p>\n

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\n\u65e2\u5b58\u60c5\u5831\u306e\u5b89\u5168\u6027\u8a66\u9a13\u306e\u8a55\u4fa1\u3067\u306f\u3001\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u3067\u3042\u308b\u300c\u3053\u3093\u306b\u3083\u304f\u7531\u6765\u30b0\u30eb\u30b3\u30b7\u30eb\u30bb\u30e9\u30df\u30c9\u300d\u3092\u542b\u3080\u539f\u6750\u6599\u3067\u3042\u308b\u300c\u3053\u3093\u306b\u3083\u304f\u828b\u7c89\u62bd\u51fa\u7269\u300d\u3092\u7528\u3044\u305f\u81e8\u5e8a\u8a66\u9a13\u306e\u5831\u544a\u304c\u3042\u3063\u305f\u3002\u3053\u3093\u306b\u3083\u304f\u828b\u7c89\u62bd\u51fa\u7269\u3092\u914d\u5408\u3057\u305f\u98f2\u6599\u306e 12\u9031\u9593\u9577\u671f\u6442\u53d6\u304a\u3088\u30734\u9031\u9593\u904e\u5270\u6442\u53d6\uff085.4mg\uff09\u8a66\u9a13\u3092\u5b9f\u65bd\u3057\u305f\u3068\u3053\u308d\u3001\u9577\u671f\u6442\u53d6\u3001\u904e\u5270\u6442\u53d6\u306b\u8d77\u56e0\u3059\u308b\u6709\u5bb3\u4e8b\u8c61\u306f\u8a8d\u3081\u3089\u308c\u306a\u304b\u3063\u305f\u3002<\/p>\n

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\u5f53\u8a72\u88fd\u54c1\u306e\u6a5f\u80fd\u6027\u306b\u95a2\u3059\u308b\u5c4a\u51fa\u8005\u306e\u8a55\u4fa1<\/h3>\n

\u3010\u6a19\u984c\u3011
\n\u30d9\u30fc\u30bf\u30ab\u30ed\u30c6\u30f3\u306b\u3088\u308b\u7d2b\u5916\u7dda\u523a\u6fc0\u304b\u3089\u808c\u3092\u4fdd\u8b77\u3059\u308b\u306e\u3092\u52a9\u3051\u308b\u6a5f\u80fd\u306b\u95a2\u3059\u308b\u7814\u7a76\u30ec\u30d3\u30e5\u30fc
\n\u3010\u76ee\u7684\u3011
\n\u5065\u5e38\u6210\u4eba\u7537\u5973\u306b\u5bfe\u3059\u308b\u30d9\u30fc\u30bf\u30ab\u30ed\u30c6\u30f3\u306e\u7d2b\u5916\u7dda\u542b\u523a\u6fc0\u304b\u3089\u808c\u3092\u4fdd\u8b77\u3059\u308b\u306e\u3092\u52a9\u3051\u308b\u6a5f\u80fd\u6027\u306b\u95a2\u3059\u308b\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30fb\u30ec\u30d3\u30e5\u30fc\u3092\u76ee\u7684\u3068\u3057\u3001\u5b9a\u6027\u7684\u306b\u8a55\u4fa1\u3057\u305f\u3002
\n\u3010\u80cc\u666f\u3011
\n\u30d9\u30fc\u30bf\u30ab\u30ed\u30c6\u30f3\u306f\u98df\u7d4c\u9a13\u8c4a\u5bcc\u306a\u30ab\u30ed\u30c6\u30ce\u30a4\u30c9\u306e\u4e00\u7a2e\u3067\u3001\u5f37\u3044\u6297\u9178\u5316\u4f5c\u7528\u304c\u3042\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u304a\u308a\u3001\u7d4c\u53e3\u6442\u53d6\u3059\u308b\u3053\u3068\u3067\u7d2b\u5916\u7dda\u7167\u5c04\u90e8\u4f4d\u306b\u304a\u3051\u308b\u7d05\u6591\u3092\u8efd\u6e1b\u3057\u808c\u3092\u4fdd\u8b77\u3059\u308b\u306e\u3092\u52a9\u3051\u308b\u3053\u3068\u306b\u95a2\u3059\u308b\u7814\u7a76\u304c\u591a\u6570\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3002\u6b27\u7c73\u3092\u4e2d\u5fc3\u306b\u305d\u306e\u6a5f\u80fd\u306f\u4e00\u822c\u7684\u306b\u3088\u304f\u77e5\u3089\u308c\u3066\u304a\u308a\u3001\u6d77\u5916\u3067\u306f\u305d\u306e\u6a5f\u80fd\u3092\u6d3b\u304b\u3057\u305f\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u7b49\u304c\u591a\u304f\u8ca9\u58f2\u3055\u308c\u3066\u3044\u308b\u3002\u65e5\u672c\u56fd\u5185\u3067\u3082\u3053\u306e\u6a5f\u80fd\u3092\u666e\u53ca\u3059\u308b\u3053\u3068\u306f\u7d2b\u5916\u7dda\u5bfe\u7b56\u306e\u9078\u629e\u80a2\u304c\u5e83\u304c\u308a\u3001QOL\uff3b\u751f\u6d3b\u306e\u8cea\uff3d\u306e\u5411\u4e0a\u306b\u5bc4\u4e0e\u3057\u3046\u308b\u3068\u8003\u3048\u3001\u672c\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\u3092\u901a\u3057\u3066\u305d\u306e\u6a5f\u80fd\u6027\u3092\u691c\u8a3c\u3057\u305f\u3002
\n\u3010\u30ec\u30d3\u30e5\u30fc\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u306e\u7279\u6027\u3011
\n\u5065\u5e38\u6210\u4eba\u7537\u5973\u306b\u304a\u3044\u3066\u3001\u30d9\u30fc\u30bf\u30ab\u30ed\u30c6\u30f3\u3092\u7d4c\u53e3\u6442\u53d6\u3057\u305f\u5834\u5408\u3068\u30d7\u30e9\u30bb\u30dc\u307e\u305f\u306f\u4ecb\u5165\u304c\u306a\u3044\u5834\u5408\u306b\u304a\u3044\u3066\u3001\u7d2b\u5916\u7dda\u523a\u6fc0\u3092\u4e0e\u3048\u305f\u969b\u306e\u7d05\u6591\u3084\u808c\u3092\u4fdd\u8b77\u3059\u308b\u306e\u3092\u52a9\u3051\u308b\u6a5f\u80fd\u6027\u306b\u95a2\u3059\u308b\u691c\u8a3c\u3092\u3057\u305f\u7814\u7a76\u3092\u691c\u7d22\u3057\u305f\u3002
\n\u691c\u7d22\u65e5\u306f2017\u5e741\u670817\u65e5\u3067\u3001\u691c\u7d22\u4ee5\u524d\u306b\u767a\u8868\u3055\u308c\u305f\u82f1\u6587\u304a\u3088\u3073\u90a6\u6587\u306e\u6587\u732e\u3092\u5bfe\u8c61\u3068\u3057\u305f\u3002\u6700\u7d42\u7684\u306b\u63a1\u7528\u3055\u308c\u305f\u6587\u732e\u6570\u306f1\u5831\u3067\u3042\u308a\u3001\u7814\u7a76\u30c7\u30b6\u30a4\u30f3\u306f\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u3067\u3042\u3063\u305f\u3002
\n\u3010\u4e3b\u306a\u7d50\u679c\u3011
\n\u5065\u5e38\u6210\u4eba\u7537\u5973\u306b\u304a\u3044\u3066\u3001\u30d9\u30fc\u30bf\u30ab\u30ed\u30c6\u30f324mg\/\u65e5\u306e12\u9031\u9593\u7d99\u7d9a\u6442\u53d6\u306f\u3001\u30d7\u30e9\u30bb\u30dc\u7fa4\u3068\u6bd4\u8f03\u3057\u3066\u7d2b\u5916\u7dda\u7167\u5c04\u90e8\u4f4d\u306b\u304a\u3051\u308b\u7d05\u6591\u3092\u6709\u610f\u306b\u8efd\u6e1b(p<0.001)\u3057\u305f\u3002\u3088\u3063\u3066\u30d9\u30fc\u30bf\u30ab\u30ed\u30c6\u30f3\u306e\u6442\u53d6\u306f\u7d2b\u5916\u7dda\u523a\u6fc0\u304b\u3089\u808c\u3092\u4fdd\u8b77\u3059\u308b\u306e\u3092\u52a9\u3051\u308b\u6a5f\u80fd\u3092\u6709\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u3002
\n\u3010\u79d1\u5b66\u7684\u6839\u62e0\u306e\u8cea\u3011
\n\u672c\u7814\u7a76\u306e\u5bfe\u8c61\u3068\u306a\u3063\u305f\u4e00\u6b21\u7814\u7a76\u306e\u53c2\u52a0\u8005\u306b\u6f5c\u5728\u7684\u306a\u30b5\u30f3\u30d7\u30ea\u30f3\u30b0\u30fb\u30d0\u30a4\u30a2\u30b9\u304c\u3042\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u304c\u3001\u3053\u308c\u306f\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30fb\u30ec\u30d3\u30e5\u30fc\u306b\u5171\u901a\u3059\u308b\u9650\u754c\u3067\u3042\u308b\u3002\u56fd\u5185\u30fb\u6d77\u5916\u306e\u8907\u6570\u306e\u6587\u732e\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u3092\u4f7f\u7528\u3057\u305f\u304c\u3001\u82f1\u6587\u3068\u90a6\u6587\u306e\u6587\u732e\u306e\u307f\u3092\u691c\u7d22\u3057\u305f\u305f\u3081\u3001\u30d1\u30d6\u30ea\u30b1\u30fc\u30b7\u30e7\u30f3\u30fb\u30d0\u30a4\u30a2\u30b9\u304c\u3042\u308b\u3053\u3068\u304c\u8003\u3048\u3089\u308c\u308b\u3002\u5bfe\u8c61\u8ad6\u6587\u306f\u30a8\u30d3\u30c7\u30f3\u30b9\u30b0\u30ec\u30fc\u30c9\u304c\u9ad8\u3044\u3068\u3055\u308c\u308bRCT\u306e\u8ad6\u6587\u3067\u3001\u63a1\u7528\u8ad6\u6587\u306f\u672c\u88fd\u54c1\u3068\u540c\u4e00\u306e\u539f\u6599\u3092\u4f7f\u7528\u3057\u305f\u8ad6\u6587\u3067\u3042\u3063\u305f\u3002\u672c\u7814\u7a76\u306e\u7d50\u8ad6\u3067\u3042\u308b\u6a5f\u80fd\u6027\u306b\u3064\u3044\u3066\u306f\u3001\u5f8c\u767a\u306e\u4e00\u6b21\u7814\u7a76\u306b\u3088\u3063\u3066\u5927\u304d\u304f\u5909\u66f4\u3055\u308c\u308b\u53ef\u80fd\u6027\u306f\u4f4e\u3044\u304c\u3001\u4e00\u65e5\u5f53\u305f\u308a\u306e\u6709\u52b9\u6442\u53d6\u91cf\u306b\u95a2\u3059\u308b\u3055\u3089\u306a\u308b\u7814\u7a76\u304c\u5831\u544a\u3055\u308c\u308b\u3053\u3068\u304c\u671b\u307e\u3057\u3044\u3002<\/p>\n

\u3010\u6a19\u984c\u3011
\nGABA\u6442\u53d6\u306b\u3088\u308b\u808c\u5f3e\u529b\u7dad\u6301\u6a5f\u80fd\u306b\u95a2\u3059\u308b\u7814\u7a76\u30ec\u30d3\u30e5\u30fc<\/p>\n

\u3010\u76ee\u7684\u3011
\n\u5065\u5eb7\u306a\u6210\u4eba\u7537\u5973\u306e\u808c\u5f3e\u529b\u7dad\u6301\u306b\u5bfe\u3059\u308bGABA\u306e\u6a5f\u80fd\u6027\u306b\u3064\u3044\u3066\u691c\u8a3c\u3059\u308b\u3053\u3068\u3092\u76ee\u7684\u3068\u3057\u305f\u3002<\/p>\n

\u3010\u80cc\u666f\u3011
\n\u65e5\u3005\u306e\u7cbe\u795e\u7684\u30fb\u8eab\u4f53\u7684\u30b9\u30c8\u30ec\u30b9\u304c\u808c\u306e\u72b6\u614b\u3092\u5de6\u53f3\u3059\u308b\u56e0\u5b50\u3067\u3042\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3002
\n\u771f\u76ae\u7d44\u7e54\u306e\u4e3b\u6210\u5206\u3067\u3042\u308b\u5f3e\u6027\u7dda\u7dad\u306f\u3001\u4f38\u3073\u7e2e\u307f\u3059\u308b\u7d44\u7e54\uff08\u76ae\u819a\u30fb\u52d5\u8108\u30fb\u80ba\u306a\u3069\uff09\u306b\u591a\u304f\u3042\u3063\u3066\u3001\u305d\u306e\u4f38\u7e2e\u6027\u3092\u62c5\u3063\u3066\u3044\u308b\u3002\u52a0\u9f62\u3084\u7d2b\u5916\u7dda\u306a\u3069\u306e\u5f71\u97ff\u306b\u3088\u3063\u3066\u5f3e\u6027\u7dda\u7dad\u306e\u52a3\u5316\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u304c\u3001\u5f3e\u6027\u7dda\u7dad\u306e\u52a3\u5316\u30fb\u65ad\u88c2\u306f\u76ae\u819a\u306e\u305f\u308b\u307f\u3060\u3051\u3067\u306a\u304f\u3001\u52d5\u8108\u4e2d\u819c\u786c\u5316\u3084\u80ba\u6c17\u816b\u306e\u76f4\u63a5\u539f\u56e0\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u308b\u3002\u307e\u305f\u5f3e\u6027\u7dda\u7dad\u306e\u4f4e\u4e0b\u306b\u3088\u308b\u771f\u76ae\u5c64\u306e\u83f2\u8584\u5316\u306f\u3001\u76ae\u819a\u306e\u8106\u5f31\u6027\uff08\u30b9\u30ad\u30f3-\u30c6\u30a2\uff09\u306b\u7e4b\u304c\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u3002\u5e73\u621030\u5e74\u5ea6\u8a3a\u7642\u5831\u916c\u6539\u5b9a\u306b\u3042\u305f\u308a\u3001\u8925\u7621\u306e\u5371\u967a\u56e0\u5b50\u306b\u76ae\u819a\u306e\u8106\u5f31\u6027\uff08\u30b9\u30ad\u30f3-\u30c6\u30a2\u306e\u4fdd\u6709\u3001\u65e2\u5f80\uff09\u304c\u52a0\u3048\u3089\u308c\u3001\u76ae\u819a\u306e\u8106\u5f31\u6027\u3092\u4e88\u9632\u3059\u308b\u305f\u3081\u306e\u6804\u990a\u98df\u54c1\u306e\u91cd\u8981\u6027\u304c\u9ad8\u307e\u3063\u3066\u3044\u308b\u3002\u3053\u308c\u3089\u306e\u4e88\u9632\u30fb\u6539\u5584\u306b\u5f79\u7acb\u3064\u98df\u54c1\u3092\u958b\u767a\u3059\u308b\u3053\u3068\u306f\u3001\u56fd\u6c11\u306e\u5065\u5eb7\u7684\u306a\u751f\u6d3b\u7dad\u6301\u306b\u304d\u308f\u3081\u3066\u91cd\u8981\u3067\u3042\u308b\u3002<\/p>\n

\u3010\u30ec\u30d3\u30e5\u30fc\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u306e\u7279\u6027\u3011
\n\u82f1\u8a9e\u3001\u65e5\u672c\u8a9e\u306e\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u3092\u691c\u7d22\u30fb\u7cbe\u67fb\u3057\u305f\u7d50\u679c\u3001\u5065\u5eb7\u306a\u6210\u4eba\u3092\u5bfe\u8c61\u3068\u3057\u3001GABA\u3068\u30d7\u30e9\u30bb\u30dc\u3092\u6bd4\u8f03\u3057\u305f\u8a66\u9a13\u3067\u3042\u308a\u3001\u808c\u306e\u5f3e\u6027\u3092\u8a55\u4fa1\u3057\u3066\u3044\u308b1\u5831\u3092\u63a1\u7528\u3057\u3001\u8a55\u4fa1\u3057\u305f\u3002<\/p>\n

\u3010\u4e3b\u306a\u7d50\u679c\u3011
\n\u63a1\u7528\u6587\u732e\u306f\u3001\u5065\u5eb7\u5973\u6027\u306b\u5bfe\u3057\u3066\u3001\u4e7e\u71e5\u3059\u308b\u6642\u671f\u306b\u3001\u808c\u5f3e\u529b\u3078\u306eGABA \u6442\u53d6\uff08100 mg\/\u65e5\uff09\u306e\u52b9\u679c\u3092\u8abf\u67fb\u3057\u3066\u304a\u308a\u3001GABA\u6442\u53d6\u7fa4\u306f\u30d7\u30e9\u30bb\u30dc\u6442\u53d6\u7fa4\u306b\u6bd4\u3079\u3066\u808c\u5f3e\u529b\u4f4e\u4e0b\u304c\u6709\u610f\u306b\u7de9\u548c\u3055\u308c\u305f\uff08P<0.05\uff09\u3053\u3068\u3092\u5831\u544a\u3057\u3066\u3044\u308b\u3002\u808c\u5f3e\u529b\u306b\u95a2\u9023\u3059\u308b\u808c\u306e\u69cb\u9020\u306f\u5168\u8eab\u3067\u5171\u901a\u3067\u3042\u308a\u3001\u6027\u5dee\u3082\u306a\u3044\u3053\u3068\u304b\u3089\u3001GABA\u306f\u808c\u306e\u5f3e\u529b\u3092\u7dad\u6301\u3057\u3001\u808c\u306e\u5065\u5eb7\u3092\u5b88\u308b\u306e\u3092\u52a9\u3051\u308b\u6a5f\u80fd\u304c\u3042\u308b\u3068\u8a55\u4fa1\u3057\u305f\u3002<\/p>\n

\u3010\u79d1\u5b66\u7684\u6839\u62e0\u306e\u8cea\u3011
\n\u63a1\u7528\u6587\u732e\u304c1\u5831\u3067\u3042\u308b\u305f\u3081\u51fa\u7248\u30d0\u30a4\u30a2\u30b9\u306f\u5426\u5b9a\u3067\u304d\u305a\u3001\u808c\u5f3e\u529b\u3092\u6e2c\u5b9a\u3057\u305f\u90e8\u4f4d\u304c\u982c\u306e\u307f\u3067\u3042\u308b\u3053\u3068\u304b\u3089\u3001\u4eca\u5f8c\u3055\u3089\u306a\u308b\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u84c4\u7a4d\u304c\u671b\u307e\u308c\u308b\u3002\u3057\u304b\u3057\u3001\u63a1\u7528\u6587\u732e\u306f\u30e9\u30f3\u30c0\u30e0\u5316\u4e8c\u91cd\u76f2\u691c\u30d7\u30e9\u30bb\u30dc\u5bfe\u7167\u4e26\u884c\u7fa4\u9593\u6bd4\u8f03\u8a66\u9a13\u306e\u67fb\u8aad\u4ed8\u304d\u8ad6\u6587\u3067\u3042\u308a\u3001\u8a55\u4fa1\u6307\u6a19\u3082\u56fd\u5185\u5916\u306b\u304a\u3044\u3066\u5e83\u304f\u7528\u3044\u3089\u308c\u3066\u3044\u308b\u624b\u6cd5\u3067\u3042\u308b\u3053\u3068\u304b\u3089\u3001\u79d1\u5b66\u7684\u6839\u62e0\u306e\u8cea\u306f\u554f\u984c\u306a\u3044\u3068\u5224\u65ad\u3057\u305f\u3002<\/p>\n

\u3010\u6a19\u984c\u3011
\n\u3053\u3093\u306b\u3083\u304f\u7531\u6765\u30b0\u30eb\u30b3\u30b7\u30eb\u30bb\u30e9\u30df\u30c9\u6442\u53d6\u306b\u3088\u308b\u7d4c\u76ae\u6c34\u5206\u84b8\u6563\u91cf\u4f4e\u4e0b\u306e\u691c\u8a3c<\/p>\n

\u3010\u76ee\u7684\u3011
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\n\u4e0a\u8a18\u76ee\u7684\u306e\u305f\u3081\u306b\u9069\u683c\u57fa\u6e96\u3068\u306a\u308bPICO\u3092\u4ee5\u4e0b\u306e\u901a\u308a\u8a2d\u5b9a\u3057\u305f\u3002
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\n\u4ecb\u5165 I(Interventions)\uff1a\u3053\u3093\u306b\u3083\u304f\u7531\u6765\u30b0\u30eb\u30b3\u30b7\u30eb\u30bb\u30e9\u30df\u30c9\u3092\u542b\u3080\u98df\u54c1\u306e\u6442\u53d6\u8a66\u9a13\u3067\u3042\u308a\u3001\u305d\u306e\u542b\u6709\u91cf\u304c\u660e\u78ba\u306a\u3082\u306e\u3068\u3057\u305f\u3002
\n\u6bd4\u8f03 C(Comparators)\uff1a\u30d7\u30e9\u30bb\u30dc\u3092\u5bfe\u7167\u3068\u3057\u3066\u8a2d\u5b9a\u3057\u305f\u3002
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\n\u7814\u7a76\u30c7\u30b6\u30a4\u30f3\uff1a\u7121\u4f5c\u70ba\u5316\u6bd4\u8f03\u8a66\u9a13\uff08RCT\uff09\u306b\u3088\u308b\u7814\u7a76\u3092\u63a1\u7528\u3057\u305f\u3002<\/p>\n

\u3010\u80cc\u666f\u3011
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\n\u691c\u7d22\u65e5\uff08\u5e73\u621030\u5e746\u67087\u65e5\uff09\u4ee5\u524d\u306b\u691c\u7d22\u30b5\u30a4\u30c8\u306b\u767b\u9332\u3055\u308c\u305f\u82f1\u6587\u53ca\u3073\u90a6\u6587\u306b\u3064\u3044\u3066\u3001\u3053\u3093\u306b\u3083\u304f\u7531\u6765\u30b0\u30eb\u30b3\u30b7\u30eb\u30bb\u30e9\u30df\u30c9\u3092\u5065\u5e38\u4eba\u306b\u7d4c\u53e3\u6442\u53d6\u3055\u305b\u3001\u808c\u3078\u306e\u4f5c\u7528\u3092\u89b3\u5bdf\u3057\u3066\u3044\u308b\u8ad6\u6587\u3092\u691c\u7d22\u3057\u305f\u3002
\n\u305d\u306e\u7d50\u679c\u3001\u4e00\u6b21\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u5f8c\u306b\u8ad6\u6587\u306f56\u5831\u3068\u306a\u3063\u305f\u3002\u30bf\u30a4\u30c8\u30eb\u3068\u8981\u65e8\u3092\u691c\u8a3c\u3057\u300150\u306e\u8ad6\u6587\u306e\u672c\u6587\u53d6\u308a\u5bc4\u305b\u3092\u5b9f\u65bd\u3057\u305f\u3002\u672c\u6587\u306e\u5185\u5bb9\u306b\u3064\u3044\u3066\u8aad\u307f\u8fbc\u307f\u3092\u5b9f\u65bd\u3057\u3066\u3001\u9069\u683c\u57fa\u6e96\u306b\u5408\u81f4\u3057\u3066\u3044\u308b\u304b\u3092\u7cbe\u67fb\u3057\u305f\u3068\u3053\u308d\u3001\u6700\u7d42\u7684\u306b5\u5831\u306e\u8ad6\u6587\u3092\u8a55\u4fa1\u5bfe\u8c61\u3068\u3057\u305f\u3002\u9664\u5916\u8ad6\u6587\u3068\u3057\u305f\u8ad6\u6587\u306b\u3064\u3044\u3066\u306f\u3001\u591a\u304f\u306f\u30d2\u30c8\u3092\u5bfe\u8c61\u3068\u3057\u305f\u8a66\u9a13\u3067\u306a\u3044\u304b\u3001\u539f\u8457\u8ad6\u6587\u3067\u306a\u304f\u89e3\u8aac\u3067\u3042\u308b\u3082\u306e\u304c\u307b\u3068\u3093\u3069\u3067\u3001\u305d\u308c\u4ee5\u5916\u306f\u30b0\u30eb\u30b3\u30b7\u30eb\u30bb\u30e9\u30df\u30c9\u4ee5\u5916\u306e\u6210\u5206\u306e\u5f71\u97ff\u304c\u6392\u9664\u3067\u304d\u306a\u3044\u3068\u3044\u3046\u7406\u7531\u3067\u9664\u5916\u3068\u3057\u305f\u3002<\/p>\n

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