{"id":21616,"date":"2022-08-31T08:10:15","date_gmt":"2022-08-30T23:10:15","guid":{"rendered":"https:\/\/yakujihou-marketing.net\/database\/?p=21616"},"modified":"2022-11-01T00:32:45","modified_gmt":"2022-10-31T15:32:45","slug":"h472","status":"publish","type":"post","link":"https:\/\/yakujihou-marketing.net\/database\/h472\/","title":{"rendered":"\u30aa\u30fc\u30e9\u30ac\u30fc\u30c9\u30d7\u30ed(H472)"},"content":{"rendered":"\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\u5c4a\u51fa\u756a\u53f7<\/td>\nH472<\/td>\n<\/tr>\n
\u5546\u54c1\u540d<\/td>\n\u30aa\u30fc\u30e9\u30ac\u30fc\u30c9\u30d7\u30ed<\/td>\n<\/tr>\n
\u5c4a\u51fa\u8005\u540d<\/td>\n\u308f\u304b\u3082\u3068\u88fd\u85ac\u682a\u5f0f\u4f1a\u793e<\/td>\n<\/tr>\n
\u5c4a\u51fa\u65e5<\/td>\n2022\/08\/31<\/td>\n<\/tr>\n
\u5909\u66f4\u65e5<\/td>\n–<\/td>\n<\/tr>\n
\u64a4\u56de\u65e5<\/td>\n–<\/td>\n<\/tr>\n
\u8ca9\u58f2\u4e2d<\/td>\n\u8ca9\u58f2\u4f11\u6b62\u4e2d<\/td>\n<\/tr>\n
\u98df\u54c1\u306e\u533a\u5206<\/td>\n\u52a0\u5de5\u98df\u54c1(\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u5f62\u72b6)<\/td>\n<\/tr>\n
\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u540d<\/td>\n\u4e73\u9178\u83ccWB21\uff08Lactobacillus salivarius WB21\uff09\u3001\u7dd1\u8336\u30d5\u30c3\u7d20\u3001\u30a8\u30d4\u30ac\u30ed\u30ab\u30c6\u30ad\u30f3\u30ac\u30ec\u30fc\u30c8\uff08EGCg\uff09<\/td>\n<\/tr>\n
\u8868\u793a\u3057\u3088\u3046\u3068\u3059\u308b\u6a5f\u80fd\u6027<\/td>\n\u672c\u54c1\u306b\u306f\u4e73\u9178\u83ccWB21\uff08Lactobacillus salivarius WB21\uff09\u3001\u7dd1\u8336\u30d5\u30c3\u7d20\u53ca\u3073\u30a8\u30d4\u30ac\u30ed\u30ab\u30c6\u30ad\u30f3\u30ac\u30ec\u30fc\u30c8\uff08EGCg\uff09\u304c\u542b\u307e\u308c\u307e\u3059\u3002\u4e73\u9178\u83ccWB21\u306b\u306f\u3001\u5065\u5eb7\u3067\u4e08\u592b\u306a\u6b6f\u3050\u304d\u3092\u7dad\u6301\u3059\u308b\u6a5f\u80fd\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u7dd1\u8336\u30d5\u30c3\u7d20\u306b\u306f\u3001\u6b6f\u306e\u518d\u77f3\u7070\u5316\u3092\u4fc3\u9032\u3057\u3001\u6b6f\u306e\u8868\u9762\u3092\u6539\u5584\u3057\u3066\u3080\u3057\u6b6f\u306e\u539f\u56e0\u3068\u306a\u308b\u9178\u306b\u6eb6\u3051\u306b\u304f\u3044\u72b6\u614b\u306b\u3059\u308b\u3053\u3068\u3067\u6b6f\u3092\u4e08\u592b\u3067\u5065\u5eb7\u306b\u3059\u308b\u6a5f\u80fd\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u30a8\u30d4\u30ac\u30ed\u30ab\u30c6\u30ad\u30f3\u30ac\u30ec\u30fc\u30c8\u306b\u306f\u3001\u53e3\u5185\u74b0\u5883\u3092\u826f\u597d\u306b\u4fdd\u3064\uff08\u6b6f\u57a2\u306e\u751f\u6210\u3092\u6291\u3048\u308b\uff09\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/td>\n<\/tr>\n
\u5f53\u8a72\u88fd\u54c1\u304c\u60f3\u5b9a\u3059\u308b\u4e3b\u306a\u5bfe\u8c61\u8005<\/td>\n\u5065\u5e38\u306a\u6210\u4eba\u7537\u5973<\/td>\n<\/tr>\n
\u4e00\u65e5\u5f53\u305f\u308a\u306e\u6442\u53d6\u76ee\u5b89\u91cf<\/td>\n2\u7c92<\/td>\n<\/tr>\n
\u4e00\u65e5\u5f53\u305f\u308a\u306e\u6442\u53d6\u76ee\u5b89\u91cf\u5f53\u305f\u308a\u306e\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u306e\u542b\u6709\u91cf<\/td>\n\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u540d\uff1a\u4e73\u9178\u83ccWB21\uff08Lactobacillus salivarius WB21\uff09\u3001\u7dd1\u8336\u30d5\u30c3\u7d20\u3001\u30a8\u30d4\u30ac\u30ed\u30ab\u30c6\u30ad\u30f3\u30ac\u30ec\u30fc\u30c8\uff08EGCg\uff09
\n\u542b\u6709\u91cf\uff1a\u4e73\u9178\u83ccWB21\uff08Lactobacillus salivarius WB21\uff094\u5104\u500b\u3001\u7dd1\u8336\u30d5\u30c3\u7d20100\u03bcg\u3001\u30a8\u30d4\u30ac\u30ed\u30ab\u30c6\u30ad\u30f3\u30ac\u30ec\u30fc\u30c8\uff08EGCg\uff0918mg<\/td>\n<\/tr>\n
\u4fdd\u5b58\u306e\u65b9\u6cd5<\/td>\n\u76f4\u5c04\u65e5\u5149\u3001\u9ad8\u6e29\u3001\u591a\u6e7f\u3092\u304a\u907f\u3051\u304f\u3060\u3055\u3044\u3002<\/td>\n<\/tr>\n
\u6442\u53d6\u306e\u65b9\u6cd5<\/td>\n\u304b\u307e\u305a\u306b\u306a\u3081\u3066\u304a\u53ec\u3057\u4e0a\u304c\u308a\u304f\u3060\u3055\u3044\u3002<\/td>\n<\/tr>\n
\u6442\u53d6\u3092\u3059\u308b\u4e0a\u3067\u306e\u6ce8\u610f\u4e8b\u9805<\/td>\n\u672c\u54c1\u306f\u3001\u591a\u91cf\u6442\u53d6\u306b\u3088\u308a\u75be\u75c5\u304c\u6cbb\u7652\u3057\u305f\u308a\u3001\u3088\u308a\u5065\u5eb7\u304c\u5897\u9032\u3059\u308b\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u539f\u6750\u6599\u3092\u3054\u78ba\u8a8d\u306e\u3046\u3048\u3001\u98df\u7269\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u3042\u308b\u65b9\u306f\u304a\u53ec\u3057\u4e0a\u304c\u308a\u306b\u306a\u3089\u306a\u3044\u3067\u304f\u3060\u3055\u3044\u3002\u7279\u306b\u964d\u5727\u5264\u3001\u6297\u51dd\u56fa\u85ac\/\u9ad8\u8840\u5c0f\u677f\u85ac\u3001\u809d\u969c\u5bb3\u3092\u5f15\u304d\u8d77\u3053\u3059\u53ef\u80fd\u6027\u306e\u3042\u308b\u533b\u85ac\u54c1\u3092\u670d\u7528\u3057\u3066\u3044\u308b\u5834\u5408\u306f\u533b\u5e2b\u306b\u76f8\u8ac7\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/td>\n<\/tr>\n
\u8abf\u7406\u53c8\u306f\u4fdd\u5b58\u306e\u65b9\u6cd5\u306b\u95a2\u3057\u7279\u306b\u6ce8\u610f\u3092\u5fc5\u8981\u3068\u3059\u308b\u3082\u306e\u306b\u3042\u3063\u3066\u306f\u5f53\u8a72\u6ce8\u610f\u4e8b\u9805<\/td>\n\u4e73\u5e7c\u5150\u53ca\u3073\u5c0f\u5150\u306e\u624b\u306e\u5c4a\u304b\u306a\u3044\u3068\u3053\u308d\u306b\u4fdd\u7ba1\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u30ad\u30b7\u30ea\u30c8\u30fc\u30eb\u304c\u542b\u307e\u308c\u3066\u3044\u307e\u3059\u306e\u3067\u3001\u72ac\u306b\u306f\u4e0e\u3048\u306a\u3044\u3067\u304f\u3060\u3055\u3044\u3002<\/td>\n<\/tr>\n
\u6d88\u8cbb\u8005\u5e81URL<\/td>\nhttps:\/\/www.fld.caa.go.jp\/caaks\/cssc02\/?recordSeq=42207250760100<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u5b89\u5168\u6027\u306b\u95a2\u3059\u308b\u57fa\u672c\u60c5\u5831<\/h2>\n

\u5b89\u5168\u6027\u306e\u8a55\u4fa1\u65b9\u6cd5<\/h3>\n

\u25a0\u65e2\u5b58\u60c5\u5831\u306b\u3088\u308b\u5b89\u5168\u6027\u8a66\u9a13\u7d50\u679c\u306e\u8a55\u4fa1\u306b\u3088\u308a\u3001\u5341\u5206\u306a\u5b89\u5168\u6027\u3092\u78ba\u8a8d\u3057\u3066\u3044\u308b\u3002<\/p>\n

\u5f53\u8a72\u88fd\u54c1\u306e\u5b89\u5168\u6027\u306b\u95a2\u3059\u308b\u5c4a\u51fa\u8005\u306e\u8a55\u4fa1<\/h3>\n

1. \u4e73\u9178\u83ccWB21\uff08Lactobacillus salivarius WB21\uff09
\n\u5c4a\u51fa\u98df\u54c1\u3068\u985e\u4f3c\u3059\u308b\u88fd\u54c1A\u306f\u3001\u5f53\u8a72\u88fd\u54c1\u306b\u542b\u307e\u308c\u308b\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u3068\u540c\u3058\u539f\u6599\uff08\u308f\u304b\u3082\u3068\u88fd\u85ac\u88fd\uff09\u3092\u4f7f\u7528\u3057\u30011\u65e5\u3042\u305f\u308a20\u5104\u500b\u306e\u914d\u5408\u91cf\u3067\u3001\u65e5\u672c\u56fd\u5185\u306b\u304a\u3044\u30662004\u5e743\u6708\u304b\u30892022\u5e743\u6708\u307e\u3067\u3067\u7d04517\u4e07\u98df\u306e\u8ca9\u58f2\u5b9f\u7e3e\u304c\u3042\u308b\u304c\u3001\u3053\u306e\u9593\u3001\u7279\u306b\u554f\u984c\u3068\u306a\u308b\u5065\u5eb7\u88ab\u5bb3\u5831\u544a\u306f\u306a\u3044\u3002\u307e\u305f\u3001\u88fd\u54c1A\u306f\u5f53\u8a72\u88fd\u54c1\u3068\u540c\u3058\u30bf\u30d6\u30ec\u30c3\u30c8\u5f62\u72b6\u3067\u3001\u6d88\u5316\u3001\u5438\u53ce\u304c\u307b\u307c\u540c\u3058\u3053\u3068\u3001\u4ed6\u306e\u914d\u5408\u6210\u5206\u306e\u5f71\u97ff\u304c\u306a\u3044\u3053\u3068\u7b49\u3001\u5c4a\u51fa\u98df\u54c1\u3068\u985e\u4f3c\u3059\u308b\u98df\u54c1\u3067\u3042\u308b3\u3064\u306e\u8981\u4ef6\u3059\u3079\u3066\u3092\u6e80\u305f\u3057\u3066\u3044\u308b\u3053\u3068\u304b\u3089\u5b89\u5168\u9762\u3067\u554f\u984c\u306a\u3044\u3068\u8003\u3048\u3089\u308c\u308b\u3002
\n2. \u7dd1\u8336\u30d5\u30c3\u7d20
\n\u30ca\u30c1\u30e5\u30e9\u30eb\u30e1\u30c7\u30a3\u30b7\u30f3\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u306b\u304a\u3044\u3066\u30d5\u30c3\u7d20\u306e\u5b89\u5168\u6027\u306b\u95a2\u3059\u308b\u60c5\u5831\u304c\u8a18\u8f09\u3055\u308c\u3066\u304a\u308a\u3001\u7d4c\u53e3\u306b\u3088\u308a\u5c11\u91cf\uff08\u57fa\u672c\u7684\u306a\u30d5\u30c3\u7d20\u91cf\u306e\u6700\u592720mg\/\u65e5\uff09\u3092\u88dc\u7d66\u3059\u308b\u5834\u5408\u3001\u307b\u3068\u3093\u3069\u306e\u4eba\u306b\u5b89\u5168\u3001\u3068\u3055\u308c\u3066\u3044\u308b\u3002\u307e\u305f\u3001\u300c\u5065\u5eb7\u98df\u54c1\u306e\u7d20\u6750\u60c5\u5831\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u300d\u306b\u304a\u3051\u308b\u30d5\u30c3\u7d20\u306e\u5b89\u5168\u6027\u60c5\u5831\u306b\u304a\u3044\u3066\u3082\u3001\u6025\u6027\u4e2d\u6bd2\u3084\u6162\u6027\u7684\u306a\u5927\u91cf\u6442\u53d6\u306b\u3088\u308b\u5f0a\u5bb3\u306b\u3064\u3044\u3066\u306e\u8a18\u8f09\u306f\u3042\u308b\u3082\u306e\u306e\u3001\u300c\u30d5\u30c3\u7d20\u5143\u7d20\u63db\u7b97\u3067\u4e0a\u9650\u6442\u53d6\u91cf10mg\/\u65e5\u4ee5\u4e0b\u3067\u3042\u308c\u3070\u5b89\u5168\u306b\u4f7f\u7528\u3067\u304d\u308b\u300d\u300c20 mg\/\u65e5\u307e\u3067\u306f\u7d4c\u53e3\u3067\u5b89\u5168\u6027\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u308b\u300d\u3068\u8a18\u8f09\u3055\u308c\u3066\u304a\u308a\u3001\u9069\u5207\u306a\u91cf\u3067\u3042\u308c\u3070\u5b89\u5168\u3067\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u3002\u3053\u308c\u3089\u306f\u3001\u3044\u305a\u308c\u3082\u7279\u5b9a\u306e\u30d5\u30c3\u7d20\u5316\u5408\u7269\u3092\u6307\u3059\u3082\u306e\u3067\u306f\u306a\u304f\u3001\u5143\u7d20\u3068\u3057\u3066\u30d5\u30c3\u7d20\u3092\u542b\u3080\u5316\u5408\u7269\u5168\u822c\u306e\u5185\u5bb9\u3067\u3042\u308a\u3001\u5f53\u8a72\u88fd\u54c1\u306b\u542b\u307e\u308c\u308b\u7dd1\u8336\u30d5\u30c3\u7d20\u306e\u8a55\u4fa1\u306b\u9069\u7528\u3067\u304d\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u3002\u5f53\u8a72\u88fd\u54c1\u306b\u542b\u307e\u308c\u308b\u7dd1\u8336\u30d5\u30c3\u7d20\u306f\u3001\u4e00\u65e5\u6442\u53d6\u76ee\u5b89\u91cf\u5f53\u305f\u308a100\u03bcg\u3067\u3042\u308a\u3001\u4e00\u65e5\u306e\u6442\u53d6\u76ee\u5b89\u91cf\u3092\u5b88\u3063\u3066\u6442\u53d6\u3059\u308b\u9650\u308a\u3001\u5b89\u5168\u6027\u306b\u554f\u984c\u306f\u306a\u3044\u3068\u5224\u65ad\u3057\u305f\u3002
\n3. \u30a8\u30d4\u30ac\u30ed\u30ab\u30c6\u30ad\u30f3\u30ac\u30ec\u30fc\u30c8\uff08EGCg\uff09
\nEGCg\u306f\u8336\u30ab\u30c6\u30ad\u30f3\u306e\u4e00\u7a2e\u3067\u3042\u308a\u3001\u8336\u30ab\u30c6\u30ad\u30f3\u304a\u3088\u3073EGCg\u306f\u3001\u65e5\u5e38\u7684\u306b\u98f2\u7528\u3057\u3066\u3044\u308b\u304a\u8336\u306b\u542b\u307e\u308c\u308b\u6210\u5206\u3067\u3001\u8336\u306f\u65e5\u672c\u306b\u304a\u3044\u30661000\u5e74\u4ee5\u4e0a\u306e\u98f2\u7528\u6b74\u304c\u3042\u308a\u3001\u53e4\u304f\u304b\u3089\u98df\u7d4c\u9a13\u306e\u3042\u308b\u6210\u5206\u3067\u3042\u308b\u3002
\n\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u5f62\u614b\u306e\u98df\u54c1\u3068\u3057\u3066\u306f\u3001\u4e00\u65e5\u6442\u53d6\u76ee\u5b89\u91cf\u5f53\u305f\u308aEGCg\u3092280\u338e\u4ee5\u4e0a\u3001\u8336\u30ab\u30c6\u30ad\u30f3\u3092500mg\u542b\u3080\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u304c2003\u5e74\u304b\u3089\u3001EGCg\u3092320\uff5e400mg\u3001\u8336\u30ab\u30c6\u30ad\u30f3\u3092520\uff5e650mg\u542b\u3080\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u304c2009\u5e74\u304b\u3089\u6d41\u901a\u3057\u3066\u304a\u308a\u3001\u8336\u30ab\u30c6\u30ad\u30f3\u304a\u3088\u3073EGCg\u306b\u8d77\u56e0\u3059\u308b\u3068\u5224\u65ad\u3055\u308c\u305f\u5065\u5eb7\u88ab\u5bb3\u306f\u5831\u544a\u3055\u308c\u3066\u3044\u306a\u3044\u3002
\n\u4ee5\u4e0a\u306e\u3053\u3068\u304b\u3089\u3001\u672c\u5c4a\u51fa\u5546\u54c1\u306e\u5b89\u5168\u6027\u8a55\u4fa1\u306f\u5341\u5206\u3067\u3042\u308b\u3068\u5224\u65ad\u3057\u305f\u3002<\/p>\n

\u6a5f\u80fd\u6027\u306b\u95a2\u3059\u308b\u57fa\u672c\u60c5\u5831<\/h2>\n

\u6a5f\u80fd\u6027\u306e\u8a55\u4fa1\u65b9\u6cd5<\/h3>\n

\u25a0\u6700\u7d42\u88fd\u54c1\u3067\u306f\u306a\u304f\u3001\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u306b\u95a2\u3059\u308b\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\u3067\u3001\u6a5f\u80fd\u6027\u3092\u8a55\u4fa1\u3057\u3066\u3044\u308b\u3002<\/p>\n

\u5f53\u8a72\u88fd\u54c1\u306e\u6a5f\u80fd\u6027\u306b\u95a2\u3059\u308b\u5c4a\u51fa\u8005\u306e\u8a55\u4fa1<\/h3>\n

1. \u4e73\u9178\u83ccWB21\uff08Lactobacillus salivarius WB21\uff09
\n\u6a19\u984c\uff1a\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u4e73\u9178\u83ccWB21\uff08Lactobacillus salivarius WB21\uff09\u3092\u7528\u3044\u305f\u5065\u5e38\u8005\u306b\u304a\u3051\u308b\u6b6f\u5468\u7d44\u7e54\u304a\u3088\u3073\u6b6f\u3050\u304d\u306e\u5065\u5eb7\u306b\u95a2\u3059\u308b\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\uff08\u5b9a\u6027\u7684\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\uff09<\/p>\n

\u76ee\u7684\uff1a\u5065\u5e38\u8005\u304c\u3001\u4e73\u9178\u83ccWB21\uff08Lactobacillus salivarius WB21\uff09\uff08\u4ee5\u4e0b\u4e73\u9178\u83ccWB21\uff09\u542b\u6709\u98df\u54c1 (\u98df\u54c1\u5f62\u614b\u306f\u554f\u308f\u306a\u3044)\u3092\u7d4c\u53e3\u6442\u53d6\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001 \u30d7\u30e9\u30bb\u30dc (\u914d\u5408\u5185\u5bb9\u306f\u554f\u308f\u306a\u3044) \u306e\u7d4c\u53e3\u6442\u53d6\u3068\u6bd4\u8f03\u3057\u3066\u3001\u6b6f\u5468\u7d44\u7e54\u304a\u3088\u3073\u6b6f\u3050\u304d\u306e\u5065\u5eb7\u3092\u7dad\u6301\u30fb\u6539\u5584\u3055\u305b\u308b\u6a5f\u80fd\u304c\u307f\u3089\u308c\u308b\u304b\u3001\u8a55\u4fa1\u3059\u308b\u3053\u3068\u3092\u76ee\u7684\u3068\u3057\u305f\u3002<\/p>\n

\u80cc\u666f\uff1a\u4e73\u9178\u83ccWB21\u306f\u3001\u30d7\u30ed\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9\u3068\u3057\u3066\u5065\u5eb7\u306e\u7dad\u6301\u304a\u3088\u3073\u5897\u9032\u306e\u305f\u3081\u306b\u5229\u7528\u3055\u308c\u308b\u4e73\u9178\u83cc\u306e\u4e00\u7a2e\u3067\u3042\u308a\u3001\u4e3b\u306b\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306a\u3069\u306e\u52a0\u5de5\u98df\u54c1\u3068\u3057\u3066\u88fd\u9020\u8ca9\u58f2\u3055\u308c\u3066\u3044\u308b\u3002\u8fd1\u5e74\u3067\u306f\u3001\u4e73\u9178\u83ccWB21\u306e\u6b6f\u79d1\u53e3\u8154\u306e\u5065\u5eb7\u3078\u306e\u6a5f\u80fd\u6027\u3082\u5831\u544a\u3055\u308c\u3066\u304a\u308a\u3001\u4e73\u9178\u83ccWB21\u306f\u9f72\u8755\u539f\u56e0\u83cc\u306e\u6291\u5236\u4f5c\u7528\u3084\u53e3\u81ed\u6539\u5584\u4f5c\u7528\u3001\u6b6f\u5468\u75c5\u539f\u83cc\u306e\u6291\u5236\u4f5c\u7528\u306a\u3069\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3002\u3055\u3089\u306b\u3001\u30d2\u30c8\u81e8\u5e8a\u8a66\u9a13\u306b\u304a\u3044\u3066\u5065\u5e38\u8005\u306e\u6b6f\u5468\u7d44\u7e54\u30fb\u6b6f\u3050\u304d\u306e\u5065\u5eb7\u3092\u7dad\u6301\u30fb\u6539\u5584\u3055\u305b\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3002\u3053\u308c\u3089\u306e\u80cc\u666f\u3092\u8e0f\u307e\u3048\u3001\u5065\u5e38\u8005\u304c\u4e73\u9178\u83ccWB21\u3092\u6442\u53d6\u3059\u308b\u3053\u3068\u3067\u3001\u6b6f\u5468\u7d44\u7e54\u30fb\u6b6f\u3050\u304d\u306e\u5065\u5eb7\u3092\u7dad\u6301\u30fb\u6539\u5584\u3059\u308b\u6a5f\u80fd\u304c\u307f\u3089\u308c\u308b\u304b\u3001\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\u3092\u5b9f\u65bd\u3057\u691c\u8a3c\u3057\u305f\u3002<\/p>\n

\u30ec\u30d3\u30e5\u30fc\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u306e\u7279\u6027\uff1a5\u3064\u306e\u96fb\u5b50\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u3092\u4f7f\u7528\u3057\u3001\u4e73\u9178\u83ccWB21\u3092\u7528\u3044\u3066\u6b6f\u5468\u7d44\u7e54\u304a\u3088\u3073\u6b6f\u3050\u304d\u306e\u5065\u5eb7\u3092\u7dad\u6301\u30fb\u6539\u5584\u3055\u305b\u308b\u6a5f\u80fd\u306b\u3064\u3044\u3066\u8abf\u67fb\u3057\u305f\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\uff08RCT\uff09\u3092\u53ce\u96c6\u3057\u305f\u3002\u8a55\u4fa1\u9805\u76ee\u300c\u6b6f\u5468\u30dd\u30b1\u30c3\u30c8\u6df1\u3055\u300d\u300cBOP\uff08\u30d7\u30ed\u30fc\u30d3\u30f3\u30b0\u6642\u306e\u51fa\u8840\uff09\u300d\u306b\u3064\u3044\u3066\u3001\u4e73\u9178\u83ccWB21\u6442\u53d6\u7fa4\u3068\u5bfe\u7167\u7fa4\uff08\u30d7\u30e9\u30bb\u30dc\u6442\u53d6\u7fa4\uff09\u306e\u30c7\u30fc\u30bf\u306b\u3064\u3044\u3066\u8abf\u67fb\u30fb\u8a55\u4fa1\u3092\u884c\u3063\u305f\u7d50\u679c\u30012\u5831\u306eRCT\u8ad6\u6587\u304c\u62bd\u51fa\u3055\u308c\u305f\u3002<\/p>\n

\u4e3b\u306a\u7d50\u679c\uff1a\u62bd\u51fa\u3055\u308c\u305f2\u5831\u306eRCT\u8ad6\u6587\u3088\u308a\u3001\u4e73\u9178\u83ccWB21\u6442\u53d6\u7fa4\u304c\u6b6f\u5468\u7d44\u7e54\u304a\u3088\u3073\u6b6f\u3050\u304d\u306e\u5065\u5eb7\u306b\u95a2\u3059\u308b\u8a55\u4fa1\u9805\u76ee\uff08\u300c\u6b6f\u5468\u30dd\u30b1\u30c3\u30c8\u6df1\u3055\u300d\u300cBOP\uff08\u30d7\u30ed\u30fc\u30d3\u30f3\u30b0\u6642\u306e\u51fa\u8840\uff09\u300d\uff09\u306b\u304a\u3044\u3066\u3001\u6b6f\u5468\u7d44\u7e54\u304a\u3088\u3073\u6b6f\u3050\u304d\u306e\u5065\u5eb7\u3092\u7dad\u6301\u30fb\u6539\u5584\u3055\u305b\u308b\u65b9\u5411\u3067\u6709\u610f\u306a\u7d50\u679c\u3092\u793a\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u3001\u4e73\u9178\u83ccWB21\u306b\u306f\u30011\u65e5\u3042\u305f\u308a\u306e\u6442\u53d6\u76ee\u5b89\u91cf4\u5104\u500b\u4ee5\u4e0a\u3092\u6442\u53d6\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u6b6f\u5468\u7d44\u7e54\u304a\u3088\u3073\u6b6f\u3050\u304d\u306e\u5065\u5eb7\u3092\u7dad\u6301\u30fb\u6539\u5584\u3055\u305b\u308b\u6a5f\u80fd\u304c\u3042\u308b\u3068\u5224\u65ad\u3055\u308c\u305f\u3002<\/p>\n

\u79d1\u5b66\u7684\u6839\u62e0\u306e\u8cea\uff1a\u672c\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\u306b\u304a\u3051\u308b\u7d50\u679c\u306e\u9650\u754c\u30fb\u554f\u984c\u70b9\u3068\u3057\u3066\u306f\u3001\u82f1\u8a9e\u304a\u3088\u3073\u65e5\u672c\u8a9e\u306e\u8ad6\u6587\u306e\u307f\u3092\u62bd\u51fa\u5bfe\u8c61\u3068\u3057\u3066\u3044\u308b\u3053\u3068\u304b\u3089\u3001\u4ed6\u306e\u8a00\u8a9e\u306b\u304a\u3051\u308b\u672c\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\u306b\u95a2\u9023\u3059\u308b\u8ad6\u6587\u306e\u5b58\u5728\u306f\u5426\u5b9a\u3067\u304d\u305a\u3001\u8a00\u8a9e\u30d0\u30a4\u30a2\u30b9\u306b\u3064\u3044\u3066\u5426\u5b9a\u3067\u304d\u306a\u3044\u3002<\/p>\n

2.\u7dd1\u8336\u30d5\u30c3\u7d20
\n\u6a19\u984c\uff1a\u7dd1\u8336\u30d5\u30c3\u7d20\u306e\u6442\u53d6\u306b\u306f\u6b6f\u306e\u518d\u77f3\u7070\u5316\u3092\u4fc3\u9032\u3057\u6b6f\u306e\u8010\u9178\u6027\u3092\u9ad8\u3081\u308b\u6a5f\u80fd\u304c\u3042\u308b\u304b<\/p>\n

\u76ee\u7684\uff1a\u5065\u5e38\u8005\u3092\u5bfe\u8c61\u306b\u3001\u7dd1\u8336\u30d5\u30c3\u7d20\u3092\u542b\u3080\u98df\u54c1\u3092\u6442\u53d6\u3055\u305b\u308b\u3068\u3001\u6b6f\u306e\u518d\u77f3\u7070\u5316\u3092\u4fc3\u9032\u3057\u3001\u6b6f\u306e\u8010\u9178\u6027\u3092\u9ad8\u3081\u308b\u304b\u306b\u3064\u3044\u3066\u691c\u8a3c\u3057\u305f\u3002<\/p>\n

\u80cc\u666f\uff1a\u6b6f\u53ca\u3073\u53e3\u8154\u306e\u5065\u5eb7\u3092\u4fdd\u3064\u3053\u3068\u306f\u3001\u98df\u7269\u3092\u5480\u56bc\u3059\u308b\u3060\u3051\u3067\u306f\u306a\u304f\u3001\u98df\u4e8b\u3084\u4f1a\u8a71\u3092\u697d\u3057\u3080\u306a\u3069\u3001\u5065\u5eb7\u3067\u8c4a\u304b\u306a\u98df\u751f\u6d3b\u3084\u793e\u4f1a\u751f\u6d3b\u3092\u9001\u308b\u4e0a\u3067\u306e\u57fa\u790e\u3068\u306a\u308b\u3002\u3057\u304b\u3057\u3001\u539a\u751f\u52b4\u50cd\u7701\u306b\u3088\u308b\u5e73\u621028\u5e74\u6b6f\u79d1\u75be\u60a3\u5b9f\u614b\u8abf\u67fb\u3067\u306f\u3001\u56fd\u6c11\u306e\u307b\u3068\u3093\u3069\u306e\u4e16\u4ee3\u306e90%\u4ee5\u4e0a\u306b\u3046\u8755\uff08\u3080\u3057\u6b6f\uff09\u304c\u3042\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3002\u30d5\u30c3\u7d20\u5316\u5408\u7269\u306f\u3001\u6b6f\u8cea\u3092\u5f37\u5316\u3059\u308b\u4f5c\u7528\u304c\u3042\u308b\u3053\u3068\u304b\u3089\u3046\u8755\u306e\u4e88\u9632\u5bfe\u7b56\u3068\u3057\u3066\u5e83\u304f\u5229\u7528\u3055\u308c\u3066\u304d\u305f\u3002\u307e\u305f\u3001\u7dd1\u8336\u30d5\u30c3\u7d20\u3092\u95a2\u4e0e\u6210\u5206\u3068\u3057\u305f\u6b6f\u3092\u4e08\u592b\u3067\u5065\u5eb7\u306b\u3059\u308b\u4fdd\u5065\u7528\u9014\u306e\u7279\u5b9a\u4fdd\u5065\u7528\u98df\u54c1\u3082\u8a31\u53ef\u3055\u308c\u3066\u3044\u308b\u3002\u3057\u304b\u3057\u3001\u7dd1\u8336\u30d5\u30c3\u7d20\u3092\u542b\u3080\u98df\u54c1\u306e\u6442\u53d6\u306b\u3088\u308b\u6b6f\u306e\u518d\u77f3\u7070\u5316\u3092\u4fc3\u9032\u3057\u6b6f\u306e\u8010\u9178\u6027\u3092\u9ad8\u3081\u308b\u4f5c\u7528\u306b\u3064\u3044\u3066\u3001\u7dcf\u5408\u7684\u306b\u8a55\u4fa1\u3057\u305f\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\u306f\u5b9f\u65bd\u3055\u308c\u3066\u3044\u306a\u3044\u3002<\/p>\n

\u65b9\u6cd5\uff1a1971\u5e74\uff5e2019\u5e74\u306b\u516c\u958b\u3055\u308c\u305f\u6587\u732e\u3092\u5bfe\u8c61\u3068\u3057\u30664\u3064\u306e\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u3092\u7528\u3044\u3001\u65e5\u672c\u8a9e\u306e\u6587\u732e\u691c\u7d22\u3001\u82f1\u8a9e\u6587\u732e\u306e\u691c\u7d22\u3092\u5b9f\u65bd\u3057\u305f\u3002\u5bfe\u8c61\u96c6\u56e3\u306f\u5065\u5e38\u8005\u3068\u3057\u3001\u7dd1\u8336\u30d5\u30c3\u7d20\u6442\u53d6\u7fa4\u3068\u30d7\u30e9\u30bb\u30dc\u6442\u53d6\u7fa4\u3068\u3092\u6bd4\u8f03\u3057\u305f\u8a66\u9a13\u30c7\u30b6\u30a4\u30f3\u3067\u3042\u308b2\u5831\u306e\u6587\u732e\u3092\u8a55\u4fa1\u3057\u305f\u3002<\/p>\n

\u4e3b\u306a\u7d50\u679c\uff1a\u9078\u5b9a\u3055\u308c\u305f2\u5831\u3092\u8a55\u4fa1\u3057\u305f\u7d50\u679c\u3001\u7dd1\u8336\u30d5\u30c3\u7d20\u3092\u542b\u3080\u98df\u54c1\u3092\u6442\u53d6\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u542b\u307e\u306a\u3044\u98df\u54c1\u3092\u6442\u53d6\u3057\u305f\u5834\u5408\u3068\u6bd4\u8f03\u3057\u3066\u3001\u6b6f\u306e\u518d\u77f3\u7070\u5316\u3092\u4fc3\u9032\u3057\u6b6f\u306e\u8010\u9178\u6027\u3092\u9ad8\u3081\u308b\u3053\u3068\u304c\u8a8d\u3081\u3089\u308c\u305f\u3002\u5f93\u3063\u3066\u3001\u7dd1\u8336\u30d5\u30c3\u7d201\u65e5\u3042\u305f\u308a100\u03bcg\u4ee5\u4e0a\u306e\u6442\u53d6\u306b\u306f\u6b6f\u306e\u518d\u77f3\u7070\u5316\u3092\u4fc3\u9032\u3059\u308b\u6a5f\u80fd\u304c\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u3002<\/p>\n

\u79d1\u5b66\u7684\u6839\u62e0\u306e\u8cea\uff1a\u9078\u5b9a\u3055\u308c\u305f\u6587\u732e\u304c2\u5831\u3060\u3063\u305f\u305f\u3081\u3001\u51fa\u7248\u30d0\u30a4\u30a2\u30b9\u306a\u3069\u306e\u8a55\u4fa1\u306b\u306f\u81f3\u3089\u305a\u3001\u672a\u5831\u544a\u7814\u7a76\u306e\u5b58\u5728\u304c\u5426\u5b9a\u3067\u304d\u306a\u3044\u3053\u3068\u304c\u7814\u7a76\u306e\u9650\u754c\u3068\u3057\u3066\u6319\u3052\u3089\u308c\u308b\u3002\u3057\u304b\u3057\u3001\u63a1\u7528\u6587\u732e\u306f\u3044\u305a\u308c\u3082\u67fb\u8aad\u4ed8\u304d\u8ad6\u6587\u3067\u7814\u7a76\u30c7\u30b6\u30a4\u30f3\u304c\u30e9\u30f3\u30c0\u30e0\u5316\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u6bd4\u8f03\u8a66\u9a13(RCT)\u3067\u3042\u3063\u305f\u305f\u3081\u3001\u79d1\u5b66\u7684\u6839\u62e0\u306e\u8cea\u306f\u9ad8\u3044\u3068\u8003\u3048\u3089\u308c\u308b\u3002\u307e\u305f\u3001\u5bfe\u8c61\u8005\u3001\u88ab\u9a13\u98df\u3001\u6bd4\u8f03\u3059\u308b\u305f\u3081\u306e\u5bfe\u7167\u3001\u8a66\u9a13\u9805\u76ee\u304c\u8abf\u67fb\u306e\u76ee\u7684\u306b\u5408\u81f4\u3057\u305f\u3082\u306e\u3067\u3042\u308a\u3001\u304b\u3064\u7d50\u679c\u306f\u80af\u5b9a\u7684\u3067\u3042\u3063\u305f\u305f\u3081\u3001\u30ec\u30d3\u30e5\u30fc\u7d50\u679c\u306f\u4fe1\u983c\u3067\u304d\u308b\u3082\u306e\u3067\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u3002<\/p>\n

3.\u30a8\u30d4\u30ac\u30ed\u30ab\u30c6\u30ad\u30f3\u30ac\u30ec\u30fc\u30c8\uff08EGCg\uff09
\n\u6a19\u984c
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