{"id":21837,"date":"2022-09-13T07:40:15","date_gmt":"2022-09-12T22:40:15","guid":{"rendered":"https:\/\/yakujihou-marketing.net\/database\/?p=21837"},"modified":"2022-11-14T02:20:57","modified_gmt":"2022-11-13T17:20:57","slug":"h529","status":"publish","type":"post","link":"https:\/\/yakujihou-marketing.net\/database\/h529\/","title":{"rendered":"\u30b9\u30eb\u30d5\u30a9\u30e9\u30d5\u30a1\u30f3\u809d\u81d3\uff21\uff2c\uff34\uff08\u30a8\u30fc\u30a8\u30eb\u30c6\u30a3\u30fc\uff09\u5024\u30b5\u30dd\u30fc\u30c8(H529)"},"content":{"rendered":"\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
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\u6d88\u8cbb\u8005\u5e81URL<\/td>\nhttps:\/\/www.fld.caa.go.jp\/caaks\/cssc02\/?recordSeq=42207120460102<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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\u5f53\u8a72\u88fd\u54c1\u306e\u6a5f\u80fd\u6027\u306b\u95a2\u3059\u308b\u5c4a\u51fa\u8005\u306e\u8a55\u4fa1<\/h3>\n

\u30a2. \u6a19\u984c
\n\u30b9\u30eb\u30d5\u30a9\u30e9\u30d5\u30a1\u30f3\u30b0\u30eb\u30b3\u30b7\u30ce\u30ec\u30fc\u30c8\u306b\u3088\u308b\u809d\u6a5f\u80fd\u30de\u30fc\u30ab\u30fc\u4f4e\u6e1b\u6a5f\u80fd\u306b\u95a2\u3059\u308b\u7814\u7a76\u30ec\u30d3\u30e5\u30fc<\/p>\n

\u30a4. \u76ee\u7684
\n\u6210\u4eba\u5065\u5e38\u8005\u3092\u5bfe\u8c61\u3068\u3057\u3066\u3001\u30b9\u30eb\u30d5\u30a9\u30e9\u30d5\u30a1\u30f3\u30b0\u30eb\u30b3\u30b7\u30ce\u30ec\u30fc\u30c8\u306e\u7d4c\u53e3\u6442\u53d6\u306b\u3088\u308b\u809d\u6a5f\u80fd\u30de\u30fc\u30ab\u30fc\u306e\u4f4e\u6e1b\u6a5f\u80fd\u306b\u3064\u3044\u3066\u8a55\u4fa1\u3057\u307e\u3057\u305f\u3002<\/p>\n

\u30a6. \u80cc\u666f
\n\u30b9\u30eb\u30d5\u30a9\u30e9\u30d5\u30a1\u30f3\u30b0\u30eb\u30b3\u30b7\u30ce\u30ec\u30fc\u30c8\uff08\u30b0\u30eb\u30b3\u30e9\u30d5\u30a1\u30cb\u30f3\uff09\u306f\u3001\u30a2\u30d6\u30e9\u30ca\u79d1\u306e\u690d\u7269\u306b\u542b\u307e\u308c\u3066\u304a\u308a\u3001\u7279\u306b\u30d6\u30ed\u30c3\u30b3\u30ea\u30fc\u306e\u65b0\u82bd\u306b\u591a\u304f\u542b\u307e\u308c\u3066\u3044\u307e\u3059\u3002\u6442\u53d6\u3057\u305f\u30b9\u30eb\u30d5\u30a9\u30e9\u30d5\u30a1\u30f3\u30b0\u30eb\u30b3\u30b7\u30ce\u30ec\u30fc\u30c8\u306f\u4f53\u5185\u3067\u30b9\u30eb\u30d5\u30a9\u30e9\u30d5\u30a1\u30f3\u306b\u4ee3\u8b1d\u3055\u308c\u3001\u5438\u53ce\u3055\u308c\u307e\u3059\u3002\u30b9\u30eb\u30d5\u30a9\u30e9\u30d5\u30a1\u30f3\u306f\u8ee2\u5199\u56e0\u5b50\u3067\u3042\u308bNuclear factor E2-related factor 2 (Nrf2)\u3092\u4ecb\u3057\u3066\u7b2c2\u76f8\u89e3\u6bd2\u9175\u7d20\u3084\u6297\u9178\u5316\u9175\u7d20\u3092\u8a98\u5c0e\u3059\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u52d5\u7269\u5b9f\u9a13\u306b\u304a\u3044\u3066\u3001\u30b9\u30eb\u30d5\u30a9\u30e9\u30d5\u30a1\u30f3\u30b0\u30eb\u30b3\u30b7\u30ce\u30ec\u30fc\u30c8\u307e\u305f\u306f\u30b9\u30eb\u30d5\u30a9\u30e9\u30d5\u30a1\u30f3\u306e\u6442\u53d6\u304c\u809d\u75be\u60a3\u4fdd\u8b77\u6a5f\u80fd\u3092\u6709\u3059\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002
\n\u3053\u306e\u3088\u3046\u306b\u3001\u30b9\u30eb\u30d5\u30a9\u30e9\u30d5\u30a1\u30f3\u30b0\u30eb\u30b3\u30b7\u30ce\u30ec\u30fc\u30c8\u306b\u306f\u809d\u6a5f\u80fd\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u304c\u3001\u5065\u5e38\u8005\u306b\u7d5e\u3063\u3066\u9577\u671f\u9593\u6442\u53d6\u3057\u305f\u969b\u306e\u809d\u6a5f\u80fd\u306b\u5bfe\u3059\u308b\u6a5f\u80fd\u3092\u8a55\u4fa1\u3057\u305f\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\u306f\u5c11\u306a\u3044\u305f\u3081\u3001\u6211\u3005\u306f\u5065\u5e38\u8005\u3092\u5bfe\u8c61\u306b\u809d\u6a5f\u80fd\u306b\u4e0e\u3048\u308b\u5f71\u97ff\u306b\u3064\u3044\u3066\u3001\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\u306e\u624b\u6cd5\u3092\u7528\u3044\u305f\u89e3\u6790\u3092\u5b9f\u65bd\u3057\u307e\u3057\u305f\u3002<\/p>\n

\u30a8. \u30ec\u30d3\u30e5\u30fc\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u306e\u7279\u6027
\n\u5916\u56fd\u8a9e\u53ca\u3073\u65e5\u672c\u8a9e\u306e\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u3092\u4f7f\u7528\u3057\u3001\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\uff08RCT\uff09\u30fb\u6e96RCT\u3092\u5bfe\u8c61\u306b\u691c\u7d22\u3092\u884c\u3044\u307e\u3057\u305f\u3002\u5bfe\u8c61\u306e\u96c6\u56e3\u306f\u3001\u5065\u5e38\u6210\u4eba\u7537\u5973\u3067\u3042\u308a\u3001\u6700\u7d42\u7684\u306b\u306f1\u5831\u306e\u8ad6\u6587\u3092\u63a1\u7528\u3057\u307e\u3057\u305f\u3002<\/p>\n

\u30aa. \u4e3b\u306a\u7d50\u679c
\n\u8a55\u4fa1\u5bfe\u8c61\u306e1\u5831\u3092\u8a55\u4fa1\u3057\u305f\u7d50\u679c\u3001\u809d\u6a5f\u80fd\u30de\u30fc\u30ab\u30fc\u306e\u4e00\u3064\u3067\u3042\u308b\u8840\u4e2dALT\u5024\u304c\u6709\u610f\u306b\u4f4e\u4e0b\u3057\u3066\u304a\u308a\u3001\u305d\u306e\u6709\u52b9\u6027\u304c\u8a8d\u3081\u3089\u308c\u3066\u3044\u307e\u3057\u305f\u3002\u307e\u305f\u3001\u5bfe\u8c61\u8005\u306f45\uff5e64\u6b73\u306e\u809d\u6a5f\u80fd\u30de\u30fc\u30ab\u30fc\u304c\u3084\u3084\u9ad8\u3081\u306e\u5065\u5e38\u7537\u5973\u3067\u3057\u305f\u3002\u4e00\u65e5\u5f53\u305f\u308a\u306e\u30b9\u30eb\u30d5\u30a9\u30e9\u30d5\u30a1\u30f3\u30b0\u30eb\u30b3\u30b7\u30ce\u30ec\u30fc\u30c8\u306e\u6442\u53d6\u91cf\u306f24 mg\u3067\u3042\u308a\u3001\u6442\u53d6\u671f\u9593\u306f24\u9031\u9593\u3067\u3057\u305f\u3002\u3057\u305f\u304c\u3063\u3066\u3001totality of evidence\u306e\u89b3\u70b9\u304b\u3089\u3001\u30b9\u30eb\u30d5\u30a9\u30e9\u30d5\u30a1\u30f3\u30b0\u30eb\u30b3\u30b7\u30ce\u30ec\u30fc\u30c8\u306e\u6442\u53d6\u306f\u3001\u809d\u6a5f\u80fd\u30de\u30fc\u30ab\u30fc\u304c\u3084\u3084\u9ad8\u3081\u306e\u4e2d\u9ad8\u9f62\u8005\u306e\u8840\u4e2dALT\u5024\u306e\u6e1b\u5c11\u306b\u95a2\u3057\u3066\u80af\u5b9a\u7684\u3067\u3042\u308b\u3068\u5224\u65ad\u3057\u307e\u3057\u305f\u3002
\n\u672c\u54c1\u306f\u4e00\u65e5\u5f53\u305f\u308a\u306e\u6442\u53d6\u76ee\u5b89\u91cf\u4e2d\u306b\u30b9\u30eb\u30d5\u30a9\u30e9\u30d5\u30a1\u30f3\u30b0\u30eb\u30b3\u30b7\u30ce\u30ec\u30fc\u30c8\u309224 mg\u542b\u3093\u3067\u304a\u308a\u3001\u809d\u6a5f\u80fd\u30de\u30fc\u30ab\u30fc\u306e\u4e00\u3064\u3067\u3042\u308b\u8840\u4e2dALT\u5024\u306e\u4f4e\u6e1b\u304c\u671f\u5f85\u3067\u304d\u308b\u3068\u5224\u65ad\u3057\u307e\u3057\u305f\u3002<\/p>\n

\u30ab. \u79d1\u5b66\u7684\u6839\u62e0\u306e\u8cea
\n\u672c\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\u3067\u306f\u3001\u30b9\u30eb\u30d5\u30a9\u30e9\u30d5\u30a1\u30f3\u30b0\u30eb\u30b3\u30b7\u30ce\u30ec\u30fc\u30c8\u306e\u6442\u53d6\u306e\u52b9\u679c\u306b\u3064\u3044\u30661\u5831\u306eRCT\u8ad6\u6587\u3092\u8a55\u4fa1\u3057\u307e\u3057\u305f\u3002\u672c\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\u306e\u9650\u754c\u3068\u3057\u3066\u3001\u63a1\u7528\u8ad6\u6587\u306f\u65e5\u672c\u4eba\u3092\u5bfe\u8c61\u3068\u3057\u3066\u3044\u307e\u3057\u305f\u304c\u3001\u8ad6\u6587\u6570\u304c1\u5831\u3057\u304b\u306a\u3044\u305f\u3081\u3001\u4eca\u5f8c\u3055\u3089\u306a\u308b\u7814\u7a76\u304c\u5fc5\u8981\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002\u307e\u305f\u3001PubMed\u3001Cochrane Library\u3001\u533b\u4e2d\u8a8cWeb\u306e3\u3064\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u3092\u7528\u3044\u3066\u3001\u82f1\u8a9e\u3001\u548c\u6587\u306e\u4e21\u65b9\u3092\u691c\u7d22\u3057\u307e\u3057\u305f\u304c\u3001\u7db2\u7f85\u7684\u306b\u691c\u7d22\u3067\u304d\u3066\u3044\u308b\u304b\u3068\u3044\u3046\u51fa\u7248\u30d0\u30a4\u30a2\u30b9\u304c\u5b58\u5728\u3059\u308b\u53ef\u80fd\u6027\u306f\u3042\u308a\u307e\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

\u5c4a\u51fa\u756a\u53f7 H529 \u5546\u54c1\u540d \u30b9\u30eb\u30d5\u30a9\u30e9\u30d5\u30a1\u30f3\u809d\u81d3\uff21\uff2c\uff34\uff08\u30a8\u30fc\u30a8\u30eb\u30c6\u30a3\u30fc\uff09\u5024\u30b5\u30dd\u30fc\u30c8 \u5c4a\u51fa\u8005\u540d \u30d7\u30e9\u30a4\u30e0\u88fd\u85ac\u5408\u540c\u4f1a\u793e \u5c4a\u51fa\u65e5 2022\/09\/13 \u5909\u66f4\u65e5 – \u64a4\u56de\u65e5 – \u8ca9\u58f2\u4e2d \u8ca9\u58f2\u4f11\u6b62\u4e2d \u98df\u54c1\u306e […]<\/p>\n","protected":false},"author":2,"featured_media":21841,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[99,177,176],"tags":[],"class_list":{"0":"post-21837","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-liver","8":"category-liver-function-enzyme","9":"category-sulforaphane-glucosinolates"},"_links":{"self":[{"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/posts\/21837","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/comments?post=21837"}],"version-history":[{"count":0,"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/posts\/21837\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/media\/21841"}],"wp:attachment":[{"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/media?parent=21837"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/categories?post=21837"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/tags?post=21837"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}