{"id":2244,"date":"2016-12-21T07:20:41","date_gmt":"2016-12-20T22:20:41","guid":{"rendered":"https:\/\/yakujihou-marketing.net\/database\/?p=2244"},"modified":"2020-03-24T05:14:49","modified_gmt":"2020-03-23T20:14:49","slug":"b405","status":"publish","type":"post","link":"https:\/\/yakujihou-marketing.net\/database\/b405\/","title":{"rendered":"\u30e1\u30bf\u30d7\u30ed\u9752\u6c41(B405)"},"content":{"rendered":"\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\u5c4a\u51fa\u756a\u53f7<\/td>\nB405<\/td>\n<\/tr>\n
\u5546\u54c1\u540d<\/td>\n\u30e1\u30bf\u30d7\u30ed\u9752\u6c41<\/td>\n<\/tr>\n
\u5c4a\u51fa\u8005\u540d<\/td>\n\u4e95\u85e4\u6f22\u65b9\u88fd\u85ac\u682a\u5f0f\u4f1a\u793e<\/td>\n<\/tr>\n
\u5c4a\u51fa\u65e5<\/td>\n2016\/12\/21<\/td>\n<\/tr>\n
\u5909\u66f4\u65e5<\/td>\n2019\/12\/23<\/td>\n<\/tr>\n
\u64a4\u56de\u65e5<\/td>\n–<\/td>\n<\/tr>\n
\u8ca9\u58f2\u4e2d<\/td>\n\u8ca9\u58f2\u4e2d<\/td>\n<\/tr>\n
\u98df\u54c1\u306e\u533a\u5206<\/td>\n\u52a0\u5de5\u98df\u54c1(\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u5f62\u72b6)<\/td>\n<\/tr>\n
\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u540d<\/td>\n\u96e3\u6d88\u5316\u6027\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09<\/td>\n<\/tr>\n
\u8868\u793a\u3057\u3088\u3046\u3068\u3059\u308b\u6a5f\u80fd\u6027<\/td>\n\u672c\u54c1\u306b\u306f\u96e3\u6d88\u5316\u6027\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u304c\u542b\u307e\u308c\u3066\u3044\u307e\u3059\u3002 \u96e3\u6d88\u5316\u6027\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u306b\u306f\u3001\u98df\u4e8b\u306b\u542b\u307e\u308c\u308b\u8102\u80aa\u306e\u5438\u53ce\u3092\u6291\u3048\u3066\u6392\u51fa\u3092\u5897\u52a0\u3055\u305b\u3001\u307e\u305f\u7cd6\u306e\u5438\u53ce\u3092\u6291\u3048\u308b\u3053\u3068\u3067\u3001\u98df\u5f8c\u306e\u8840\u4e2d\u4e2d\u6027\u8102\u80aa\u3084\u8840\u7cd6\u5024\u306e\u4e0a\u6607\u3092\u6291\u3048\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u4fbf\u901a\u3092\u6539\u5584\u3059\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u672c\u54c1\u306f\u98df\u5f8c\u306e\u8840\u7cd6\u5024\u3084\u8102\u80aa\u304c\u6c17\u306b\u306a\u308b\u65b9\u3001\u304a\u306a\u304b\u306e\u8abf\u5b50\u3092\u6574\u3048\u305f\u3044\u65b9\u306b\u9069\u3057\u3066\u3044\u307e\u3059\u3002<\/td>\n<\/tr>\n
\u5f53\u8a72\u88fd\u54c1\u304c\u60f3\u5b9a\u3059\u308b\u4e3b\u306a\u5bfe\u8c61\u8005<\/td>\n\u5065\u5e38\u6210\u4eba\u3002\u98df\u5f8c\u306e\u8840\u7cd6\u5024\u3084\u8102\u80aa\u304c\u6c17\u306b\u306a\u308b\u65b9\u3001\u304a\u306a\u304b\u306e\u8abf\u5b50\u3092\u6574\u3048\u305f\u3044\u65b9\u3002<\/td>\n<\/tr>\n
\u4e00\u65e5\u5f53\u305f\u308a\u306e\u6442\u53d6\u76ee\u5b89\u91cf<\/td>\n\u98df\u4e8b\u306e\u969b\u306b1\u65e51\u888b\uff088.5g\uff09\u3092\u76ee\u5b89\u306b\u3001150\uff5e200ml\u306e\u6c34\u306a\u3069\u306b\u6eb6\u304b\u3057\u3066\u304a\u53ec\u3057\u4e0a\u304c\u308a\u304f\u3060\u3055\u3044\u3002\u203b\u534a\u91cf\u7a0b\u5ea6\u306e\u6c34\u306a\u3069\u306e\u4e2d\u306b\u7c89\u672b\u3092\u3088\u304f\u6df7\u305c\u305f\u5f8c\u3001\u6b8b\u91cf\u3092\u52a0\u3048\u308b\u3068\u6eb6\u304b\u3057\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002\u203b\u304a\u597d\u307f\u306b\u3088\u308a\u6c34\u306a\u3069\u306e\u91cf\u3092\u8abf\u7bc0\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u203b\u6eb6\u304b\u3057\u305f\u6642\u306b\u3001\u5927\u9ea6\u82e5\u8449\u672b\u306a\u3069\u306e\u690d\u7269\u7531\u6765\u306e\u7e4a\u7dad\u3084\u767d\u8272\u6210\u5206\u304c\u6d6e\u904a\u30fb\u6c88\u6bbf\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u306e\u3067\u3001\u304b\u304d\u6df7\u305c\u306a\u304c\u3089\u304a\u53ec\u3057\u4e0a\u304c\u308a\u304f\u3060\u3055\u3044\u3002\u226a\u300e\u6442\u53d6\u306e\u65b9\u6cd5\u300f\u3068\u4f75\u305b\u3066\u8868\u793a\u226b<\/td>\n<\/tr>\n
\u4e00\u65e5\u5f53\u305f\u308a\u306e\u6442\u53d6\u76ee\u5b89\u91cf\u5f53\u305f\u308a\u306e\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u306e\u542b\u6709\u91cf<\/td>\n\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u540d\uff1a\u96e3\u6d88\u5316\u6027\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09
\n\u542b\u6709\u91cf\uff1a5,000mg<\/td>\n<\/tr>\n
\u4fdd\u5b58\u306e\u65b9\u6cd5<\/td>\n\u9ad8\u6e29\u30fb\u591a\u6e7f\u3001\u76f4\u5c04\u65e5\u5149\u3092\u907f\u3051\u3001\u6dbc\u3057\u3044\u6240\u306b\u4fdd\u7ba1\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/td>\n<\/tr>\n
\u6442\u53d6\u306e\u65b9\u6cd5<\/td>\n\u98df\u4e8b\u306e\u969b\u306b1\u65e51\u888b\uff088.5g\uff09\u3092\u76ee\u5b89\u306b\u3001150\uff5e200ml\u306e\u6c34\u306a\u3069\u306b\u6eb6\u304b\u3057\u3066\u304a\u53ec\u3057\u4e0a\u304c\u308a\u304f\u3060\u3055\u3044\u3002\u203b\u534a\u91cf\u7a0b\u5ea6\u306e\u6c34\u306a\u3069\u306e\u4e2d\u306b\u7c89\u672b\u3092\u3088\u304f\u6df7\u305c\u305f\u5f8c\u3001\u6b8b\u91cf\u3092\u52a0\u3048\u308b\u3068\u6eb6\u304b\u3057\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002\u203b\u304a\u597d\u307f\u306b\u3088\u308a\u6c34\u306a\u3069\u306e\u91cf\u3092\u8abf\u7bc0\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u203b\u6eb6\u304b\u3057\u305f\u6642\u306b\u3001\u5927\u9ea6\u82e5\u8449\u672b\u306a\u3069\u306e\u690d\u7269\u7531\u6765\u306e\u7e4a\u7dad\u3084\u767d\u8272\u6210\u5206\u304c\u6d6e\u904a\u30fb\u6c88\u6bbf\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u306e\u3067\u3001\u304b\u304d\u6df7\u305c\u306a\u304c\u3089\u304a\u53ec\u3057\u4e0a\u304c\u308a\u304f\u3060\u3055\u3044\u3002\u226a\u300e\u4e00\u65e5\u5f53\u305f\u308a\u306e\u6442\u53d6\u76ee\u5b89\u91cf\u300f\u3068\u4f75\u305b\u3066\u8868\u793a\u226b<\/td>\n<\/tr>\n
\u6442\u53d6\u3092\u3059\u308b\u4e0a\u3067\u306e\u6ce8\u610f\u4e8b\u9805<\/td>\n\u25cf\u6442\u308a\u904e\u304e\u3001\u3042\u308b\u3044\u306f\u4f53\u8cea\u30fb\u4f53\u8abf\u306b\u3088\u308a\u304a\u306a\u304b\u304c\u3086\u308b\u304f\u306a\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002
\n\u25cf\uff11\u65e5\u306e\u6442\u53d6\u76ee\u5b89\u91cf\u3092\u5b88\u3063\u3066\u304f\u3060\u3055\u3044\u3002
\n\u25cf\u888b\u958b\u5c01\u5f8c\u306f\u3059\u3050\u306b\u304a\u53ec\u3057\u4e0a\u304c\u308a\u304f\u3060\u3055\u3044\u3002
\n\u25cf\u98df\u7269\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u3042\u308b\u65b9\u306f\u539f\u6750\u6599\u540d\u3092\u3054\u78ba\u8a8d\u304f\u3060\u3055\u3044\u3002<\/td>\n<\/tr>\n
\u8abf\u7406\u53c8\u306f\u4fdd\u5b58\u306e\u65b9\u6cd5\u306b\u95a2\u3057\u7279\u306b\u6ce8\u610f\u3092\u5fc5\u8981\u3068\u3059\u308b\u3082\u306e\u306b\u3042\u3063\u3066\u306f\u5f53\u8a72\u6ce8\u610f\u4e8b\u9805<\/td>\n\u25cf\u8fb2\u7523\u7269\u7531\u6765\u306e\u539f\u6599\u3092\u4f7f\u7528\u3057\u3066\u3044\u308b\u305f\u3081\u3001\u5546\u54c1\u306b\u3088\u308a\u3001\u5473\u3084\u8272\u3001\u9999\u308a\u304c\u591a\u5c11\u7570\u306a\u308b\u5834\u5408\u3082\u3042\u308a\u307e\u3059\u304c\u3001\u54c1\u8cea\u306b\u306f\u554f\u984c\u3042\u308a\u307e\u305b\u3093\u3002
\n\u25cf\u4e73\u5e7c\u5150\u306e\u624b\u306e\u5c4a\u304b\u306a\u3044\u6240\u306b\u4fdd\u7ba1\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/td>\n<\/tr>\n
\u6d88\u8cbb\u8005\u5e81URL<\/td>\nhttps:\/\/www.fld.caa.go.jp\/caaks\/cssc02\/?recordSeq=41911220090503<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u5b89\u5168\u6027\u306b\u95a2\u3059\u308b\u57fa\u672c\u60c5\u5831<\/h2>\n

\u5b89\u5168\u6027\u306e\u8a55\u4fa1\u65b9\u6cd5<\/h3>\n

\u25a0\u55ab\u98df\u5b9f\u7e3e\u306e\u8a55\u4fa1\u306b\u3088\u308a\u3001\u5341\u5206\u306a\u5b89\u5168\u6027\u3092\u78ba\u8a8d\u3057\u3066\u3044\u308b\u3002<\/p>\n

\u5f53\u8a72\u88fd\u54c1\u306e\u5b89\u5168\u6027\u306b\u95a2\u3059\u308b\u5c4a\u51fa\u8005\u306e\u8a55\u4fa1<\/h3>\n

\u672c\u5c4a\u51fa\u54c1\u306f2008\u5e74\u306b\u8ca9\u58f2\u3092\u958b\u59cb\u3057\u3001\u3053\u308c\u307e\u306720\u4e07\u500b\u4ee5\u4e0a\u306e\u8ca9\u58f2\u5b9f\u7e3e\u304c\u3042\u308a\u307e\u3059\u304c\u3001
\n\u3053\u308c\u307e\u3067\u306e\u8ca9\u58f2\u671f\u9593\u4e2d\u306b\u5f53\u8a72\u5546\u54c1\u304c\u539f\u56e0\u3068\u5224\u65ad\u3067\u304d\u308b\u5065\u5eb7\u88ab\u5bb3\u306f\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002
\n\u4ee5\u4e0a\u306e\u55ab\u98df\u7d4c\u9a13\u306b\u3088\u308a\u5f53\u8a72\u5546\u54c1\u306e\u5b89\u5168\u6027\u3092\u78ba\u8a8d\u3057\u3066\u304a\u308a\u307e\u3059\u3002<\/p>\n

\u6a5f\u80fd\u6027\u306b\u95a2\u3059\u308b\u57fa\u672c\u60c5\u5831<\/h2>\n

\u6a5f\u80fd\u6027\u306e\u8a55\u4fa1\u65b9\u6cd5<\/h3>\n

\u25a0\u6700\u7d42\u88fd\u54c1\u3067\u306f\u306a\u304f\u3001\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u306b\u95a2\u3059\u308b\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\u3067\u3001\u6a5f\u80fd\u6027\u3092\u8a55\u4fa1\u3057\u3066\u3044\u308b\u3002<\/p>\n

\u5f53\u8a72\u88fd\u54c1\u306e\u6a5f\u80fd\u6027\u306b\u95a2\u3059\u308b\u5c4a\u51fa\u8005\u306e\u8a55\u4fa1<\/h3>\n

\u8a55\u4fa1\u3059\u308b\u6a5f\u80fd\u6027\u306e\u5831\u544a\uff1a\u8840\u4e2d\u4e2d\u6027\u8102\u80aa\u306e\u4e0a\u6607\u6291\u5236
\n(\u30a2) \u6a19\u984c
\n\u96e3\u6d88\u5316\u6027\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u306e\u6442\u53d6\u304c\u98df\u5f8c\u306e\u8840\u4e2d\u4e2d\u6027\u8102\u80aa\u306e\u4e0a\u6607\u6291\u5236\u306b\u53ca\u307c\u3059\u5f71\u97ff<\/p>\n

(\u30a4)\u76ee\u7684
\n\u5065\u5e38\u6210\u4eba\u3082\u3057\u304f\u306f\u7a7a\u8179\u6642\u8840\u4e2d\u4e2d\u6027\u8102\u80aa\u5024\u304c\u3084\u3084\u9ad8\u3081\u306e\u6210\u4eba\u306b\u5bfe\u3057\u3066\u96e3\u6d88\u5316\u6027\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u3092\u6442\u53d6\u3059\u308b\u3053\u3068\u3067\u3001\u98df\u5f8c\u8840\u4e2d\u4e2d\u6027\u8102\u80aa\u5024\u306e\u4e0a\u6607\u6291\u5236\u4f5c\u7528\u304c\u898b\u3089\u308c\u308b\u304b\u3092\u78ba\u8a8d\u3059\u308b\u3053\u3068\u3092\u76ee\u7684\u3068\u3057\u305f\u3002<\/p>\n

(\u30a6) \u80cc\u666f
\n\u65e5\u672c\u306b\u304a\u3044\u3066\u3001\u96e3\u6d88\u5316\u6027\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u306f\u3001\u5e73\u621027\u5e749\u67084\u65e5\u6642\u70b9\u3067387\u54c1\u76ee\u306e\u7279\u5b9a\u4fdd\u5065\u7528\u98df\u54c1\u306b\u4f7f\u7528\u3055\u308c\u3001\u300c\u98df\u5f8c\u306e\u8840\u4e2d\u4e2d\u6027\u8102\u80aa\u5024\u306e\u4e0a\u6607\u3092\u6291\u5236\u3059\u308b\u300d\u3068\u3044\u3063\u305f\u8868\u793a\u5185\u5bb9\u306e\u8a31\u53ef\u3092\u53d7\u3051\u305f\u7279\u5b9a\u4fdd\u5065\u7528\u98df\u54c1\u306f16\u54c1\u76ee\u3042\u308b\u3002\u305d\u3053\u3067\u3001\u96e3\u6d88\u5316\u6027\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u306e\u98df\u5f8c\u8840\u4e2d\u4e2d\u6027\u8102\u80aa\u5024\u306e\u4e0a\u6607\u6291\u5236\u4f5c\u7528\u306b\u95a2\u3059\u308b\u8a55\u4fa1\u3092\u884c\u3063\u305f\u3002<\/p>\n

(\u30a8) \u30ec\u30d3\u30e5\u30fc\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u306e\u7279\u6027
\n\u672c\u7814\u7a76\u306e\u30c7\u30b6\u30a4\u30f3\u306f\u3001\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\uff08\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\uff09\u3067\u3059\u3002\u6587\u732e\u691c\u7d22\u306bPubMed\u3001Cochrane Library\uff082015\u5e741\u67085\u65e5\u691c\u7d22\u5b9f\u65bd\uff09\u3001\u533b\u4e2d\u8a8cWeb\u3001CiNii Articles\uff082014\u5e7412\u670815\u65e5\u691c\u7d22\u5b9f\u65bd\uff09\u306e\u96fb\u5b50\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u3092\u4f7f\u7528\u3057\u3001\u3059\u3079\u3066\u306e\u671f\u9593\u3092\u5bfe\u8c61\u671f\u9593\u3068\u3057\u3066\u3001\u5065\u5e38\u6210\u4eba\u3082\u3057\u304f\u306f\u7a7a\u8179\u6642\u8840\u4e2d\u4e2d\u6027\u8102\u80aa\u5024\u304c\u3084\u3084\u9ad8\u3081\u306e\u6210\u4eba\u3092\u5bfe\u8c61\u306b\u96e3\u6d88\u5316\u6027\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u3092\u7528\u3044\u3066\u98df\u5f8c\u8840\u4e2d\u4e2d\u6027\u8102\u80aa\u5024\u306e\u4e0a\u6607\u6291\u5236\u4f5c\u7528\u306b\u3064\u3044\u3066\u8abf\u67fb\u3057\u305f\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\uff08RCT\uff09\u3092\u53ce\u96c6\u3057\u305f\u3002\u5404RCT\u8ad6\u6587\u306e\u8cea\u306e\u8a55\u4fa1\u3092\u884c\u3044\u30014\u3064\u306e\u8a55\u4fa1\u9805\u76ee\u300c\u98df\u5f8c\u8840\u4e2d\u4e2d\u6027\u8102\u80aa\u5024\uff082,3,4\u6642\u9593\uff09\u300d\u304a\u3088\u3073\u300c\u8840\u4e2d\u6fc3\u5ea6\u66f2\u7dda\u4e0b\u9762\u7a4d\uff08AUC0-6h\uff09\u300d\u306e\u5b9f\u6e2c\u5024\u304a\u3088\u3073\u5909\u5316\u91cf\u306b\u3064\u3044\u3066\u3001\u96e3\u6d88\u5316\u6027\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u6442\u53d6\u7fa4\u3068\u5bfe\u7167\u7fa4\u306e\u5dee\u306e\u30c7\u30fc\u30bf\u3092\u7d71\u5408\u3057\u305f\u3002<\/p>\n

(\u30aa) \u4e3b\u306a\u7d50\u679c
\n\u62bd\u51fa\u3055\u308c\u305f9\u5831\u306eRCT\u8ad6\u6587\u306b\u304a\u3044\u3066\u3001\u7d71\u8a08\u89e3\u6790\u306e\u7d50\u679c\u3001\u5168\u3066\u306e\u8a55\u4fa1\u9805\u76ee\u306b\u304a\u3044\u3066\u3001\u5bfe\u7167\u7fa4\u3068\u6bd4\u8f03\u3057\u3066\u96e3\u6d88\u5316\u6027\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u6442\u53d6\u7fa4\u304c\u3001\u98df\u5f8c\u8840\u4e2d\u4e2d\u6027\u8102\u80aa\u5024\u3092\u6709\u610f\u306b\u4f4e\u4e0b\u3055\u305b\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u305f\u3002\u672c\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\u306f\u63a1\u7528\u57fa\u6e96\u3068\u3057\u3066\u3001\u5065\u5e38\u6210\u4eba\u3082\u3057\u304f\u306f\u7a7a\u8179\u6642\u8840\u4e2d\u4e2d\u6027\u8102\u80aa\u5024\u304c\u3084\u3084\u9ad8\u3081\u306e\u6210\u4eba\u3092\u5bfe\u8c61\u3068\u3057\u3066\u3044\u308b\u304c\u30019\u5831\u5168\u3066\u306e\u8ad6\u6587\u306b\u7a7a\u8179\u6642\u8840\u4e2d\u4e2d\u6027\u8102\u80aa\u5024\u304c\u3084\u3084\u9ad8\u3081\u306e\u6210\u4eba\u304c\u542b\u307e\u308c\u3066\u3044\u305f\u3002\u305d\u3053\u3067\u30019\u5831\u306e\u3046\u3061\u539f\u30c7\u30fc\u30bf\u3092\u78ba\u8a8d\u3067\u304d\u308b\u8ad6\u65871\u5831\u306b\u3064\u3044\u3066\u5065\u5e38\u6210\u4eba\u306e\u307f\u3067\u518d\u5ea6\u3001\u5c64\u5225\u89e3\u6790\u3092\u884c\u3044\u3001\u5225\u9014\u5b9a\u6027\u8a55\u4fa1\u3092\u884c\u3063\u305f\u7d50\u679c\u3001\u5065\u5e38\u6210\u4eba\u306b\u304a\u3044\u3066\u3082\u672c\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\u306e\u7d50\u679c\u306b\u80af\u5b9a\u7684\u3067\u3042\u3063\u305f\u3053\u3068\u304b\u3089\u3001\u79d1\u5b66\u7684\u6839\u62e0\u304c\u3042\u308b\u3068\u5224\u65ad\u3057\u305f\u3002\u306a\u304a\u3001\u96e3\u6d88\u5316\u6027\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u306e\u4e00\u56de\u63a8\u5968\u6442\u53d6\u76ee\u5b89\u91cf\u306f\u30015g\u304c\u59a5\u5f53\u3068\u8003\u3048\u3089\u308c\u305f\u3002<\/p>\n

(\u30ab) \u79d1\u5b66\u7684\u6839\u62e0\u306e\u8cea
\n\u30a8\u30d3\u30c7\u30f3\u30b9\u7dcf\u4f53\u306e\u8cea\u306e\u8a55\u4fa1\u306b\u304a\u3044\u3066\u3001\u5168\u3066\u306e\u30a2\u30a6\u30c8\u30ab\u30e0\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u5f37\u3055\u306fA\uff08\u5f37\u3044\uff09\u3068\u5224\u65ad\u3055\u308c\u305f\u3002<\/p>\n

(\u30ad) \u7814\u7a76\u306e\u9650\u754c
\n\u4eca\u5f8c\u306e\u7814\u7a76\u306b\u3088\u3063\u3066\u306f\u3001\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\u306e\u7d50\u679c\u304c\u5909\u308f\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u305f\u3081\u3001\u7d99\u7d9a\u3057\u305f\u8abf\u67fb\u304c\u5fc5\u8981\u3067\u3042\u308b\u3002\u307e\u305f\u3001\u98df\u4e8b\u7642\u6cd5\u3060\u3051\u3067\u306a\u304f\u3001\u904b\u52d5\u7642\u6cd5\u3001\u305d\u306e\u4ed6\u751f\u6d3b\u7fd2\u6163\u306a\u3069\u3068\u306e\u4ea4\u7d61\u56e0\u5b50\u306e\u5f71\u97ff\u306b\u3064\u3044\u3066\u3001\u7d99\u7d9a\u3057\u305f\u7814\u7a76\u304c\u5fc5\u8981\u3068\u8003\u3048\u3089\u308c\u308b\u3002<\/p>\n

\uff08\u69cb\u9020\u5316\u6284\u9332\uff09<\/p>\n

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\n(\u30a2) \u6a19\u984c
\n\u96e3\u6d88\u5316\u6027\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u306e\u6442\u53d6\u304c\u98df\u5f8c\u8840\u7cd6\u5024\u306e\u4e0a\u6607\u6291\u5236\u306b\u53ca\u307c\u3059\u5f71\u97ff<\/p>\n

(\u30a4)\u76ee\u7684
\n\u5065\u5e38\u6210\u4eba\u3082\u3057\u304f\u306f\u5883\u754c\u57df\u8840\u7cd6\u5024\u306e\u6210\u4eba\u306b\u5bfe\u3057\u3066\u3001\u96e3\u6d88\u5316\u6027\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u3092\u6442\u53d6\u3059\u308b\u3053\u3068\u3067\u3001\u98df\u5f8c\u8840\u7cd6\u5024\u306e\u4e0a\u6607\u6291\u5236\u4f5c\u7528\u304c\u898b\u3089\u308c\u308b\u304b\u3092\u78ba\u8a8d\u3059\u308b\u3053\u3068\u3092\u76ee\u7684\u3068\u3057\u305f\u3002<\/p>\n

(\u30a6) \u80cc\u666f
\n\u65e5\u672c\u306b\u304a\u3044\u3066\u3001\u96e3\u6d88\u5316\u6027\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u306f\u3001\u5e73\u621027\u5e749\u67084\u65e5\u6642\u70b9\u3067387\u54c1\u76ee\u306e\u7279\u5b9a\u4fdd\u5065\u7528\u98df\u54c1\u306b\u4f7f\u7528\u3055\u308c\u3001\u300c\u98df\u5f8c\u8840\u7cd6\u5024\u306e\u4e0a\u6607\u3092\u6291\u5236\u3059\u308b\u300d\u3068\u3044\u3063\u305f\u8868\u793a\u5185\u5bb9\u306e\u8a31\u53ef\u3092\u53d7\u3051\u305f\u7279\u5b9a\u4fdd\u5065\u7528\u98df\u54c1\u306f190\u54c1\u76ee\u3042\u308b\u3002\u305d\u3053\u3067\u3001\u96e3\u6d88\u5316\u6027\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u306e\u98df\u5f8c\u8840\u7cd6\u5024\u306e\u4e0a\u6607\u6291\u5236\u4f5c\u7528\u306b\u95a2\u3059\u308b\u8a55\u4fa1\u3092\u884c\u3063\u305f\u3002<\/p>\n

(\u30a8) \u30ec\u30d3\u30e5\u30fc\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u306e\u7279\u6027
\n\u672c\u7814\u7a76\u306e\u30c7\u30b6\u30a4\u30f3\u306f\u3001\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\uff08\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\uff09\u3067\u3059\u3002\u6587\u732e\u691c\u7d22\u306bPubMed\u3001Cochrane Library\uff082015\u5e741\u67085\u65e5\u691c\u7d22\u5b9f\u65bd\uff09\u3001\u533b\u4e2d\u8a8cWeb\u3001CiNii Articles\uff082014\u5e7412\u670815\u65e5\u691c\u7d22\u5b9f\u65bd\uff09\u306e\u96fb\u5b50\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u3092\u4f7f\u7528\u3057\u3001\u3059\u3079\u3066\u306e\u671f\u9593\u3092\u5bfe\u8c61\u671f\u9593\u3068\u3057\u3066\u3001\u5065\u5e38\u6210\u4eba\u3082\u3057\u304f\u306f\u5883\u754c\u57df\u8840\u7cd6\u5024\u306e\u6210\u4eba\u3092\u5bfe\u8c61\u306b\u96e3\u6d88\u5316\u6027\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u3092\u7528\u3044\u3066\u98df\u5f8c\u8840\u7cd6\u5024\u306e\u4e0a\u6607\u6291\u5236\u4f5c\u7528\u306b\u3064\u3044\u3066\u8abf\u67fb\u3057\u305f\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\uff08RCT\uff09\u3092\u53ce\u96c6\u3057\u305f\u3002\u5404RCT\u8ad6\u6587\u306e\u8cea\u306e\u8a55\u4fa1\u3092\u884c\u3044\u30013\u3064\u306e\u8a55\u4fa1\u9805\u76ee\u300c\u98df\u5f8c\u8840\u7cd6\u502430\u5206\u300d\u3001\u300c\u98df\u5f8c\u8840\u7cd6\u502460\u5206\u300d\u3001\u300c\u98df\u5f8c\u8840\u7cd6\u5024\u306e\u6fc3\u5ea6\u66f2\u7dda\u4e0b\u9762\u7a4d\uff08AUC0-120min\uff09\u300d\u306b\u3064\u3044\u3066\u3001\u96e3\u6d88\u5316\u6027\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u6442\u53d6\u7fa4\u3068\u5bfe\u7167\u7fa4\u306e\u5dee\u306e\u30c7\u30fc\u30bf\u3092\u7d71\u5408\u3057\u305f\u3002<\/p>\n

(\u30aa) \u4e3b\u306a\u7d50\u679c
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(\u30ab) \u79d1\u5b66\u7684\u6839\u62e0\u306e\u8cea
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