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\u6d88\u8cbb\u8005\u5e81URL<\/td>\nhttps:\/\/www.fld.caa.go.jp\/caaks\/cssc02\/?recordSeq=42303170010102<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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\u6a5f\u80fd\u6027\u306e\u8a55\u4fa1\u65b9\u6cd5<\/h3>\n

\u25a0\u6700\u7d42\u88fd\u54c1\u3067\u306f\u306a\u304f\u3001\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u306b\u95a2\u3059\u308b\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\u3067\u3001\u6a5f\u80fd\u6027\u3092\u8a55\u4fa1\u3057\u3066\u3044\u308b\u3002<\/p>\n

\u5f53\u8a72\u88fd\u54c1\u306e\u6a5f\u80fd\u6027\u306b\u95a2\u3059\u308b\u5c4a\u51fa\u8005\u306e\u8a55\u4fa1<\/h3>\n

\uff1c\u7c73\u7531\u6765\u30b0\u30eb\u30b3\u30b7\u30eb\u30bb\u30e9\u30df\u30c9\u306b\u3064\u3044\u3066\uff1e
\n\uff11\uff0e\u6a19\u984c
\n\u7c73\u7531\u6765\u30b0\u30eb\u30b3\u30b7\u30eb\u30bb\u30e9\u30df\u30c9\u6442\u53d6\u306e\u7d4c\u76ae\u6c34\u5206\u84b8\u6563\u91cf\uff08\u76ae\u819a\u30d0\u30ea\u30a2\u6a5f\u80fd\uff09\u6539\u5584\u306b\u95a2\u3059\u308b\u8a55\u4fa1<\/p>\n

\uff12\uff0e\u76ee\u7684
\n\u808c\u304c\u4e7e\u71e5\u3057\u304c\u3061\u306a\u5065\u5e38\u8005\uff08\u76ae\u819a\u75be\u60a3\u306b\u7f79\u60a3\u3057\u3066\u3044\u306a\u3044\u304c\u3001\u4e7e\u71e5\u306b\u3088\u308b\u808c\u8352\u308c\u306e\u81ea\u899a\u75c7\u72b6\u3092\u6709\u3059\u308b\u65b9\uff09\u306b\u304a\u3044\u3066\u7c73\u7531\u6765\u30b0\u30eb\u30b3\u30b7\u30eb\u30bb\u30e9\u30df\u30c9\uff08GlcCer\uff09\u306e\u7d4c\u53e3\u6442\u53d6\u306f\u3001\u5bfe\u7167\u7fa4\uff08\u30d7\u30e9\u30bb\u30dc\uff09\u3068\u6bd4\u8f03\u3057\u3066\u76ae\u819a\u30d0\u30ea\u30a2\u6a5f\u80fd\u3092\u6539\u5584\u3059\u308b\u304b\u306b\u3064\u3044\u3066\u3001\u7d4c\u76ae\u6c34\u5206\u84b8\u6563\u91cf(TEWL)\u3092\u6307\u6a19\u3068\u3057\u3066\u5b9f\u65bd\u3055\u308c\u305f\u30d2\u30c8\u81e8\u5e8a\u8a66\u9a13\u306e\u7d50\u679c\u3092\u901a\u3057\u3066\u691c\u8a3c\u30fb\u8003\u5bdf\u3057\u307e\u3057\u305f\u3002<\/p>\n

\uff13\uff0e\u80cc\u666f
\nGlcCer\u306f\u3001\u7c73\u3001\u3068\u3046\u3082\u308d\u3053\u3057\u3001\u3053\u3093\u306b\u3083\u304f\u7b49\u3092\u306f\u3058\u3081\u69d8\u3005\u306a\u690d\u7269\u3084\u98df\u54c1\u7d20\u6750\u306b\u542b\u307e\u308c\u3066\u3044\u307e\u3059\u3002\u4e2d\u3067\u3082\u7c73\u7531\u6765GlcCer\u306b\u3064\u3044\u3066\u306f\u3001\u7d4c\u53e3\u6442\u53d6\u306e\u524d\u5f8c\u6bd4\u8f03\u3067\u808c\u3078\u306e\u6709\u52b9\u6027\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u305d\u308c\u3089\u3092\u7db2\u7f85\u7684\u306b\u89e3\u6790\u3057\u305f\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n

\uff14\uff0e\u30ec\u30d3\u30e5\u30fc\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u306e\u7279\u6027
\n\u5065\u5eb7\u306a\u6210\u4eba\u7537\u5973\u306b\u3064\u3044\u3066\u3001\u7c73\u7531\u6765GlcCer\u3092\u7d4c\u53e3\u6442\u53d6\u3057\u305f\u3068\u304d\u306b\u3001\u6442\u53d6\u524d\u5f8c\u53ca\u3073\u5bfe\u7167\u7fa4\u3068\u306e\u6bd4\u8f03\u306b\u3088\u3063\u3066TEWL\u304c\u6539\u5584\u3059\u308b\u304b\u3069\u3046\u304b\u3092\u8a55\u4fa1\u3057\u305f\u7814\u7a76\u3067\u3001\u67fb\u8aad\u4ed8\u304d\u8ad6\u6587\u3068\u3057\u3066\u5b66\u8853\u96d1\u8a8c\u306b\u63b2\u8f09\u3055\u308c\u305fRCT\uff08\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\uff09\u3092\u5bfe\u8c61\u306b\u3001\u82f1\u8a9e\u53ca\u3073\u65e5\u672c\u8a9e\u6587\u732e\u691c\u7d22\u30b5\u30a4\u30c8\u3092\u7528\u3044\u30662016\u5e742\u6708\u306b\u691c\u7d22\u3001\u8a55\u4fa1\u3057\u307e\u3057\u305f\u3002\uff08\u5bfe\u8c61\u671f\u9593\u306f1926\u5e74\u304b\u3089\u691c\u7d22\u65e5\u307e\u3067\uff09
\n\u305d\u306e\u7d50\u679c\u3001\u63a1\u7528\u8ad6\u6587\u306f\uff11\u5831\u3067\u3057\u305f\u304c\u3001\u7814\u7a76\u306e\u8cea\u306e\u8a55\u4fa1\u3092\u884c\u306a\u3063\u305f\u3068\u3053\u308d\u3001\u4fe1\u983c\u6027\u306e\u9ad8\u3044\u30d7\u30e9\u30bb\u30dc\u5bfe\u7167RCT\u3067\u3042\u308a\u3001\u7814\u7a76\u9014\u4e0a\u3067\u306e\u75c7\u4f8b\u6e1b\u5c11\u3001\u7814\u7a76\u5b9f\u65bd\u8a08\u753b\u66f8\u304c\u4e8b\u524d\u306b\u767b\u9332\u3055\u308c\u3066\u3044\u306a\u304b\u3063\u305f\u3053\u3068\u7b49\u306b\u30de\u30a4\u30ca\u30b9\u8981\u56e0\u306f\u3042\u308b\u3082\u306e\u306e\u3001\u8a55\u4fa1\u3092\u4e0b\u3052\u308b\u5fc5\u8981\u6027\u306f\u4f4e\u3044\u3068\u5224\u65ad\u3057\u3001\u63a1\u7528\u8ad6\u6587\u306e\u7814\u7a76\u306f\u8cea\u7684\u306b\u9ad8\u304f\u826f\u597d\u3068\u8003\u3048\u307e\u3057\u305f\u3002<\/p>\n

\uff15\uff0e\u4e3b\u306a\u52b9\u679c
\n\u63a1\u7528\u6587\u732e\u306e\u7814\u7a76\u3067\u306f\u3001\u4e7e\u71e5\u306a\u3069\u306b\u3088\u308b\u808c\u8352\u308c\u3092\u81ea\u899a\u3057\u3066\u304a\u308aTEWL\u306e\u9ad8\u3044\u5065\u5eb7\u306a\u6210\u4eba\u7537\u5973133\u540d\u3092\u5bfe\u8c61\u3068\u3057\u3066\u3001GlcCer\u3092\u542b\u3080\u7c73\u80da\u82bd\u30a8\u30ad\u30b9\u304c\u5168\u8eab\u306eTEWL\u3092\u6539\u5584\u3059\u308b\u304b\u5426\u304b\u306b\u3064\u3044\u3066\u3001\u30d7\u30e9\u30bb\u30dc\u5bfe\u7167\u30e9\u30f3\u30c0\u30e0\u5316\u4e8c\u91cd\u906e\u853d\u4e26\u884c\u7fa4\u9593\u6bd4\u8f03\u8a66\u9a13\u306b\u304a\u3044\u3066\u691c\u8a0e\u3055\u308c\u307e\u3057\u305f\u3002\u7c73\u7531\u6765GlcCer\u6442\u53d6\u7fa4\uff08\u8a66\u9a13\u7fa4\uff09\u306e\u88ab\u9a13\u8005\u306f\u3001GlcCer 1.8 mg\u3092\u542b\u3080\u7c73\u80da\u82bd\u30a8\u30ad\u30b9\u3092\u914d\u5408\u3057\u305f\u7c89\u672b\u9846\u7c92\u30921\u65e51\u5305\uff081.5 g\uff09\u3001\u30d7\u30e9\u30bb\u30dc\u6442\u53d6\u7fa4\uff08\u5bfe\u7167\u7fa4\uff09\u306e\u88ab\u9a13\u8005\u306f\u3001\u5916\u89b3\u3001\u5f62\u72b6\u3001\u98a8\u5473\u306b\u304a\u3044\u3066\u8a66\u9a13\u54c1\u3068\u8b58\u5225\u4e0d\u80fd\u306a\u7c73\u80da\u82bd\u30a8\u30ad\u30b9\u672a\u914d\u5408\u306e\u7c89\u672b\u9846\u7c92\u3092\u305d\u308c\u305e\u308c12\u9031\u9593\u6442\u53d6\u3057\u307e\u3057\u305f\u3002
\n\u305d\u306e\u7d50\u679c\u3001\u8a66\u9a13\u7fa4\u3067\u306f\u5bfe\u7167\u7fa4\u306b\u6bd4\u8f03\u3057\u3066TEWL\u306e\u521d\u671f\u5024\u306b\u5bfe\u3059\u308b\u5909\u5316\u91cf\u306b\u6709\u610f\u306a\u5dee\u304c\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\u3002
\n\u3053\u308c\u306b\u3088\u308a\u3001\u7c73\u7531\u6765GlcCer\uff081.8 mg\/\u65e5\uff09\u3092\u6442\u53d6\u3059\u308b\u3053\u3068\u3067\u3001\u808c\u304c\u4e7e\u71e5\u3057\u304c\u3061\u306a\u6210\u4eba\u5065\u5e38\u8005\u306eTEWL\u3092\u6539\u5584\u3059\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n

\uff16\uff0e\u79d1\u5b66\u7684\u6839\u62e0\u306e\u8cea
\n\u63a1\u7528\u6587\u732e\u306f\u67fb\u8aad\u4ed8\u304d\u3067\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u8cea\u306f\u9ad8\u3044\u3068\u8003\u3048\u307e\u3059\u304c\u30011\u5831\u3068\u5c11\u306a\u3044\u305f\u3081\u3001\u4eca\u5f8c\u3001\u3088\u308a\u8cea\u306e\u9ad8\u3044\u7814\u7a76\u6210\u679c\u304c\u5831\u544a\u3055\u308c\u308b\u3053\u3068\u304c\u671b\u307e\u3057\u3044\u3068\u8003\u3048\u307e\u3059\u3002<\/p>\n

\uff1c\u30d2\u30cf\u30c4\u7531\u6765\u30d4\u30da\u30ea\u30f3\u985e\u306b\u3064\u3044\u3066\uff1e
\n\u3010\u51b7\u3048\u306b\u3088\u308a\u4f4e\u4e0b\u3057\u305f\u8840\u6d41\uff08\u672b\u68a2\u8840\u6d41\uff09\u3092\u6b63\u5e38\u306b\u6574\u3048\u3001\u51b7\u3048\u306b\u3088\u308b\u672b\u68a2\uff08\u624b\uff09\u306e\u76ae\u819a\u8868\u9762\u6e29\u5ea6\u306e\u4f4e\u4e0b\u3092\u8efd\u6e1b\u3059\u308b\u6a5f\u80fd\u306b\u3064\u3044\u3066\u3011
\n\u30a2\u3000\u6a19\u984c
\n\u300c\u30d2\u30cf\u30c4\u7531\u6765\u30d4\u30da\u30ea\u30f3\u985e\u300d\u6442\u53d6\u306b\u3088\u3063\u3066\u3001\u51b7\u3048\u306b\u3088\u308a\u4f4e\u4e0b\u3057\u305f\u8840\u6d41\uff08\u672b\u68a2\u8840\u6d41\uff09\u3092\u6b63\u5e38\u306b\u6574\u3048\u3001\u51b7\u3048\u306b\u3088\u308b\u672b\u68a2\u306e\u76ae\u819a\u8868\u9762\u6e29\u5ea6\u306e\u4f4e\u4e0b\u3092\u8efd\u6e1b\u3059\u308b\u6a5f\u80fd\u306b\u95a2\u3059\u308b\u5b9a\u6027\u7684\u7814\u7a76\u30ec\u30d3\u30e5\u30fc
\n\u30a4\u3000\u76ee\u7684
\n\u5065\u5eb7\u306a\u65b9\u306b\u5bfe\u3059\u308b\u300c\u30d2\u30cf\u30c4\u7531\u6765\u30d4\u30da\u30ea\u30f3\u985e\u300d\u6442\u53d6\u306e\u52b9\u679c\u3092\u3001\u30d7\u30e9\u30bb\u30dc\u3068\u306e\u6bd4\u8f03\u3067\u691c\u8a3c\u3057\u305f\u7814\u7a76\u3092\u30ec\u30d3\u30e5\u30fc\u3057\u3001\u52b9\u679c\u306e\u6709\u7121\u3092\u7dcf\u5408\u7684\u306b\u8a55\u4fa1\u3057\u307e\u3057\u305f\u3002
\n\u30a6\u3000\u80cc\u666f
\n\u30d2\u30cf\u30c4\u306f\u3001\u9999\u8f9b\u6599\u7b49\u3068\u3057\u3066\u5229\u7528\u3055\u308c\u3066\u304a\u308a\u3001\u6210\u5206\u3068\u3057\u3066\u30d4\u30da\u30ea\u30f3\u985e\u3092\u542b\u307f\u307e\u3059\u3002TRPV1\u3092\u6d3b\u6027\u5316\u3059\u308b\u4f5c\u7528\u304b\u3089\u3001\u51b7\u3048\u306b\u3088\u3063\u3066\u4f4e\u4e0b\u3059\u308b\u8840\u6d41\uff08\u672b\u68a2\u8840\u6d41\uff09\u3084\u76ae\u819a\u8868\u9762\u6e29\u5ea6\u306e\u7dad\u6301\u306b\u5f79\u7acb\u3064\u3068\u63a8\u6e2c\u3055\u308c\u307e\u3059\u304c\u3001\u30d2\u30c8\u3067\u306e\u6709\u52b9\u6027\u3092\u5305\u62ec\u7684\u306b\u6574\u7406\u3059\u308b\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\u306f\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u3057\u305f\u304c\u3063\u3066\u3001\u5065\u5eb7\u306a\u65b9\u304c\u30d2\u30cf\u30c4\u7531\u6765\u30d4\u30da\u30ea\u30f3\u985e\u3092\u6442\u53d6\u3057\u305f\u5834\u5408\u306b\u304a\u3051\u308b\u51b7\u3048\u306b\u3088\u308b\u8840\u6d41\uff08\u672b\u68a2\u8840\u6d41\uff09\u304a\u3088\u3073\u76ae\u819a\u8868\u9762\u6e29\u5ea6\u306e\u4f4e\u4e0b\u3092\u8efd\u6e1b\u3059\u308b\u52b9\u679c\u306b\u3064\u3044\u3066\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\u3092\u884c\u3044\u3001\u305d\u306e\u79d1\u5b66\u7684\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u78ba\u8a8d\u3092\u884c\u3044\u307e\u3057\u305f\u3002
\n\u30a8\u3000\u30ec\u30d3\u30e5\u30fc\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u306e\u7279\u6027
\n\u56fd\u5185\u5916\u306e\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u3092\u4f7f\u7528\u3057\u3066\u8ad6\u6587\u3092\u691c\u7d22\u3057\u3001\u57fa\u6e96\u306b\u5408\u81f4\u3057\u305f\u6587\u732e\uff11\u5831\uff08\u30e9\u30f3\u30c0\u30e0\u5316\u4e8c\u91cd\u76f2\u691c\u30d7\u30e9\u30bb\u30dc\u5bfe\u7167\u30af\u30ed\u30b9\u30aa\u30fc\u30d0\u30fc\u8a66\u9a13\uff09\u3092\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\u306e\u5bfe\u8c61\u3068\u3057\u307e\u3057\u305f\u3002
\n\u30aa\u3000\u4e3b\u306a\u7d50\u679c
\n\u4e0a\u8a18\u6587\u732e\u306f\u5065\u5eb7\u306a\u65e5\u672c\u4eba\u6210\u4eba\u5973\u6027\u304c\u3001\u30d2\u30cf\u30c4\u7531\u6765\u30d4\u30da\u30ea\u30f3\u985e120\u03bcg\u542b\u6709\u30d2\u30cf\u30c4\u62bd\u51fa\u7269\u3092\u6442\u53d6\u3059\u308b\u3053\u3068\u3067\u3001\u30d7\u30e9\u30bb\u30dc\u3092\u6442\u53d6\u3057\u305f\u5834\u5408\u3068\u6bd4\u8f03\u3057\u3066\u3001\u51b7\u6c34\u8ca0\u8377\u5f8c\u306e\u672b\u68a2\u8840\u6d41\u91cf\u304a\u3088\u3073\u624b\uff08\u672b\u68a2\uff09\u306e\u76ae\u819a\u8868\u9762\u6e29\u5ea6\u304c\u7d71\u8a08\u5b66\u7684\u306b\u6709\u610f\u306b\u9ad8\u304f\u306a\u3063\u3066\u304a\u308a\uff08p<0.05\uff09\u3001\u51b7\u3048\u306b\u3088\u308a\u4f4e\u4e0b\u3057\u305f\u8840\u6d41\uff08\u672b\u68a2\u8840\u6d41\uff09\u3092\u6b63\u5e38\u306b\u6574\u3048\u3001\u51b7\u3048\u306b\u3088\u308b\u672b\u68a2\uff08\u624b\uff09\u306e\u76ae\u819a\u8868\u9762\u6e29\u5ea6\u306e\u4f4e\u4e0b\u3092\u8efd\u6e1b\u3059\u308b\u52b9\u679c\u304c\u8a8d\u3081\u3089\u308c\u3066\u3044\u307e\u3057\u305f\u3002
\n\u30ab\u3000\u79d1\u5b66\u7684\u6839\u62e0\u306e\u8cea
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\u5c4a\u51fa\u756a\u53f7 I159 \u5546\u54c1\u540d \u3081\u3050\u308a\u30e2\u30a4\u30b9\u30c8 \u5c4a\u51fa\u8005\u540d \u682a\u5f0f\u4f1a\u793e\u30cb\u30c3\u30d7\u30f3 \u5c4a\u51fa\u65e5 2023\/05\/01 \u5909\u66f4\u65e5 – \u64a4\u56de\u65e5 – \u8ca9\u58f2\u4e2d \u8ca9\u58f2\u4f11\u6b62\u4e2d \u98df\u54c1\u306e\u533a\u5206 \u52a0\u5de5\u98df\u54c1(\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u5f62\u72b6) \u6a5f\u80fd\u6027\u95a2 […]<\/p>\n","protected":false},"author":2,"featured_media":25862,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[17,16,264,88,222,112,267,31,106],"tags":[128],"class_list":{"0":"post-25858","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-skin","8":"category-moisturizing","9":"category-hand","10":"category-blood-flow","11":"category-leg","12":"category-body-temperature-expression","13":"category-swelling","14":"category-glucosylceramide","15":"category-piperine","16":"tag-woman"},"_links":{"self":[{"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/posts\/25858","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/comments?post=25858"}],"version-history":[{"count":0,"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/posts\/25858\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/media\/25862"}],"wp:attachment":[{"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/media?parent=25858"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/categories?post=25858"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/tags?post=25858"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}