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\u6d88\u8cbb\u8005\u5e81URL<\/td>\nhttps:\/\/www.fld.caa.go.jp\/caaks\/s\/cssc01\/fwccd01?c__id=a09F900004skLq6IAE<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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\u4ee5\u4e0a\u3088\u308a\u3001\u672c\u54c1\u306e\u4e00\u65e5\u6442\u53d6\u76ee\u5b89\u91cf\u3092\u5b88\u3063\u3066\u9069\u5207\u306b\u4f7f\u7528\u3059\u308c\u3070\u3001\u5b89\u5168\u6027\u306b\u554f\u984c\u306f\u7121\u3044\u3068\u5224\u65ad\u3057\u305f\u3002<\/p>\n

\uff1c\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u540c\u58eb\u306e\u76f8\u4e92\u4f5c\u7528\u306b\u3064\u3044\u3066\uff1e
\n\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9(PubMed)\u306b\u3066\u691c\u7d22\u30fb\u60c5\u5831\u53ce\u96c6\u3092\u304a\u3053\u306a\u3063\u305f\u304c\u3001\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u540c\u58eb\u306e\u76f8\u4e92\u4f5c\u7528\u306e\u5831\u544a\u306f\u5f97\u308b\u3053\u3068\u304c\u3067\u304d\u306a\u304b\u3063\u305f\u305f\u3081\u3001\u554f\u984c\u306a\u3044\u3068\u5224\u65ad\u3057\u305f\u3002<\/p>\n

\u6a5f\u80fd\u6027\u306b\u95a2\u3059\u308b\u57fa\u672c\u60c5\u5831<\/h2>\n

\u6a5f\u80fd\u6027\u306e\u8a55\u4fa1\u65b9\u6cd5<\/h3>\n

\u25a0\u6700\u7d42\u88fd\u54c1\u3067\u306f\u306a\u304f\u3001\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u306b\u95a2\u3059\u308b\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\u3067\u3001\u6a5f\u80fd\u6027\u3092\u8a55\u4fa1\u3057\u3066\u3044\u308b\u3002<\/p>\n

\u5f53\u8a72\u88fd\u54c1\u306e\u6a5f\u80fd\u6027\u306b\u95a2\u3059\u308b\u5c4a\u51fa\u8005\u306e\u8a55\u4fa1<\/h3>\n

\u25a0\u30aa\u30ea\u30fc\u30d6\u7531\u6765\u30d2\u30c9\u30ed\u30ad\u30b7\u30c1\u30ed\u30bd\u30fc\u30eb
\n\u3010\u6a19\u984c\u3011\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u30aa\u30ea\u30fc\u30d6\u7531\u6765\u30d2\u30c9\u30ed\u30ad\u30b7\u30c1\u30ed\u30bd\u30fc\u30eb\u3092\u7528\u3044\u305f\u5065\u5e38\u8005\u306b\u304a\u3051\u308bLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u9178\u5316\u3092\u6291\u5236\u3057\u3001\u9178\u5316LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3092\u4f4e\u4e0b\u3059\u308b\u6a5f\u80fd\u306b\u95a2\u3059\u308b\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\uff08\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\uff09<\/p>\n

\u3010\u76ee\u7684\u3011\u672c\u7814\u7a76\u306e\u76ee\u7684\u306f\u3001P: \u75be\u75c5\u306b\u7f79\u60a3\u3057\u3066\u3044\u306a\u3044\u5065\u5e38\u8005\u306b\u5bfe\u3057\u3066\u3001I: \u30aa\u30ea\u30fc\u30d6\u7531\u6765\u30d2\u30c9\u30ed\u30ad\u30b7\u30c1\u30ed\u30bd\u30fc\u30eb\u542b\u6709\u98df\u54c1(\u98df\u54c1\u5f62\u614b\u306f\u554f\u308f\u306a\u3044)\u3092\u7d4c\u53e3\u6442\u53d6\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001C: \u30d7\u30e9\u30bb\u30dc(\u914d\u5408\u5185\u5bb9\u306f\u554f\u308f\u306a\u3044)\u306e\u7d4c\u53e3\u6442\u53d6\u3068\u6bd4\u8f03\u3057\u3066\u3001O: LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u9178\u5316\u3092\u6291\u5236\u3057\u3001\u9178\u5316LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3092\u4f4e\u4e0b\u3059\u308b\u6a5f\u80fd\u304c\u307f\u3089\u308c\u308b\u304b\u8a55\u4fa1\u3092\u884c\u3046\u3053\u3068\u3067\u3042\u308b\u3002<\/p>\n

\u3010\u80cc\u666f\u3011\u52d5\u8108\u786c\u5316\u306e\u767a\u75c7\u30fb\u9032\u5c55\u306b\u306f\u4ee3\u8b1d\u7570\u5e38\u3084\u708e\u75c7\u3001\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u306a\u3069\u69d8\u3005\u306a\u8981\u56e0\u304c\u95a2\u4e0e\u3057\u3066\u3044\u308b\u304c\u3001\u9178\u5316LDL\u304c\u52d5\u8108\u786c\u5316\u306e\u4e2d\u5fc3\u7684\u306a\u539f\u56e0\u3068\u3055\u308c\u3066\u3044\u308b\u30022008\u5e74\u306b\u8840\u4e2d\u9178\u5316LDL\u5b9a\u91cf\u6cd5\u306e\u5065\u5eb7\u4fdd\u967a\u9069\u5fdc\u304c\u8a8d\u3081\u3089\u308c\u3001\u52d5\u8108\u786c\u5316\u306e\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u3068\u3057\u3066\u306e\u6709\u7528\u6027\u304c\u793a\u3055\u308c\u305f\u3002EFSA\uff08\u6b27\u5dde\u98df\u54c1\u5b89\u5168\u6a5f\u95a2\uff09\u306f\u3001\u30aa\u30ea\u30fc\u30d6\u7531\u6765\u306e\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u3067\u3042\u308b\u30d2\u30c9\u30ed\u30ad\u30b7\u30c1\u30ed\u30bd\u30fc\u30eb\u3068\u305d\u306e\u8a98\u5c0e\u4f53\u304cLDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u9178\u5316\u5909\u6027\u3092\u9632\u3050\u6a5f\u80fd\u3092\u6301\u3064\u3053\u3068\u3092\u8a8d\u3081\u3066\u3044\u308b\u3002\u3053\u306e\u30ec\u30d3\u30e5\u30fc\u3067\u306f\u3001\u30aa\u30ea\u30fc\u30d6\u7531\u6765\u30d2\u30c9\u30ed\u30ad\u30b7\u30c1\u30ed\u30bd\u30fc\u30eb\u306e\u6442\u53d6\u304c\u8840\u4e2d\u9178\u5316LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u52b9\u679c\u3092\u691c\u8a3c\u3057\u305f\u3002<\/p>\n

\u3010\u30ec\u30d3\u30e5\u30fc\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u306e\u7279\u6027\u3011\u8907\u6570\u306e\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u3092\u4f7f\u7528\u3057\u3066\u82f1\u8a9e\u304a\u3088\u3073\u65e5\u672c\u8a9e\u306e\u6587\u732e\u691c\u7d22\u3092\u884c\u3044\u3001\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\uff08RCT\uff09\u30c7\u30b6\u30a4\u30f3\u306e4\u3064\u306e\u7814\u7a76\u8ad6\u6587\u3092\u63a1\u629e\u3057\u305f\u3002<\/p>\n

\u3010\u4e3b\u306a\u7d50\u679c\u3011\u30aa\u30ea\u30fc\u30d6\u7531\u6765\u30d2\u30c9\u30ed\u30ad\u30b7\u30c1\u30ed\u30bd\u30fc\u30eb\u30921\u65e5\u3042\u305f\u308a1.59mg\u304b\u308915mg\u6442\u53d6\u3059\u308b\u3053\u3068\u3067\u3001\u8840\u4e2d\u9178\u5316LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u6709\u610f\u306b\u4f4e\u4e0b\u3059\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u305f\u3002<\/p>\n

\u3010\u79d1\u5b66\u7684\u6839\u62e0\u306e\u8cea\u3011\u672c\u30ec\u30d3\u30e5\u30fc\u306e\u9650\u754c\u306f\u3001\u82f1\u8a9e\u304a\u3088\u3073\u65e5\u672c\u8a9e\u306e\u8ad6\u6587\u306e\u307f\u3092\u5bfe\u8c61\u3068\u3057\u3066\u3044\u308b\u305f\u3081\u3001\u4ed6\u306e\u8a00\u8a9e\u306e\u95a2\u9023\u8ad6\u6587\u304c\u5b58\u5728\u3059\u308b\u53ef\u80fd\u6027\u3092\u6392\u9664\u3067\u304d\u305a\u3001\u8a00\u8a9e\u30d0\u30a4\u30a2\u30b9\u304c\u3042\u308b\u304b\u3082\u3057\u308c\u306a\u3044\u3002\u3057\u304b\u3057\u3001\u8a55\u4fa1\u5bfe\u8c61\u306f\u8cea\u306e\u9ad8\u3044\u81e8\u5e8a\u8a66\u9a13\u3067\u3042\u308bRCT\u3067\u3042\u308a\u3001\u307e\u305fEFSA\u3067\u3082\u540c\u69d8\u306e\u6a5f\u80fd\u6027\u304c\u8a8d\u3081\u3089\u308c\u3066\u3044\u308b\u3053\u3068\u304b\u3089\u3001\u79d1\u5b66\u7684\u6839\u62e0\u306e\u8cea\u306f\u9ad8\u3044\u3068\u8003\u3048\u3089\u308c\u308b\u3002<\/p>\n

\u25a0\u30a8\u30e9\u30b0\u9178
\n\u3010\u6a19\u984c\u3011
\n\u30a8\u30e9\u30b0\u9178\u306e\u6442\u53d6\u306b\u3088\u308b\u5065\u5e38\u6210\u4eba\u306e\u4f53\u91cd\u3084\u4f53\u8102\u80aa\u306b\u53ca\u307c\u3059\u5f71\u97ff\u306b\u95a2\u3059\u308b\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc<\/p>\n

\u3010\u76ee\u7684\u3011
\n\u75be\u75c5\u306b\u7f79\u60a3\u3057\u3066\u3044\u306a\u3044\u6210\u4eba\u7537\u5973\u304c\u30a8\u30e9\u30b0\u9178\u3092\u7d4c\u53e3\u6442\u53d6\u3057\u305f\u969b\u306e\u5065\u5e38\u6210\u4eba\u306e\u4f53\u91cd\u3084\u4f53\u8102\u80aa\u306b\u53ca\u307c\u3059\u5f71\u97ff\u3092\u691c\u8a3c\u3059\u308b\u3002<\/p>\n

\u3010\u80cc\u666f\u3011
\n\u30a8\u30e9\u30b0\u9178\u306f\u30b6\u30af\u30ed\u3084\u30a4\u30c1\u30b4\u3001\u30e9\u30ba\u30d9\u30ea\u30fc\u3001\u30ca\u30c3\u30c4\u3001\u30a2\u30d5\u30ea\u30ab\u30de\u30f3\u30b4\u30fc\u306a\u3069\u306b\u5929\u7136\u306b\u542b\u307e\u308c\u308b\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u306e\u4e00\u7a2e\u3067\u3001\u5f37\u3044\u6297\u9178\u5316\u4f5c\u7528\u304c\u3042\u308b\u3053\u3068\u304b\u3089\u8840\u6db2\u4e2d\u306e\u904e\u9178\u5316\u8102\u8cea\u3092\u6291\u3048\u3001\u8102\u80aa\u7d30\u80de\u306e\u80a5\u5927\u5316\u3092\u9632\u304e\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u5206\u6ccc\u3092\u963b\u5bb3\u3059\u308b\u30db\u30eb\u30e2\u30f3\uff08\u30ec\u30b8\u30b9\u30c1\u30f3\uff09\u306e\u5206\u6ccc\u3092\u6291\u3048\u308b\u52b9\u679c\u304c\u3042\u308b\u3068\u3055\u308c\u3066\u3044\u308b\u3002\u4ed6\u65b9\u3001\u73fe\u4ee3\u65e5\u672c\u3067\u306f\u98df\u4e8b\u6b27\u7c73\u5316\u3001\u6162\u6027\u7684\u306a\u904b\u52d5\u4e0d\u8db3\u304b\u3089\u80a5\u6e80\u8005\u304c\u5897\u3048\u3066\u3044\u308b\u3002\u80a5\u6e80\u306f\u751f\u6d3b\u7fd2\u6163\u75c5\u3092\u306f\u3058\u3081\u3068\u3057\u3066\u6570\u591a\u304f\u306e\u75be\u60a3\u306e\u3082\u3068\u3068\u306a\u308a\u3001\u5065\u5eb7\u3065\u304f\u308a\u306b\u304a\u3044\u3066\u80a5\u6e80\u306e\u4e88\u9632\u30fb\u6539\u5584\u306f\u5927\u304d\u306a\u610f\u5473\u3092\u6301\u3064\u3002\u30a8\u30e9\u30b0\u9178\u306f\u80a5\u6e80\u6539\u5584\u306b\u52b9\u679c\u304c\u3042\u308b\u6210\u5206\u3068\u3057\u3066\u8fd1\u5e74\u6ce8\u76ee\u3092\u6d74\u3073\u3066\u3044\u308b\u6210\u5206\u3067\u3042\u308b\u304c\u5065\u5e38\u6210\u4eba\u3092\u5bfe\u8c61\u3068\u3057\u305f\u30ec\u30d3\u30e5\u30fc\u306f\u6570\u5c11\u306a\u3044\u3002\u305d\u306e\u305f\u3081\u3001\u30a8\u30e9\u30b0\u9178\u306e\u5065\u5e38\u6210\u4eba\u306e\u4f53\u91cd\u3084\u4f53\u8102\u80aa\u306b\u53ca\u307c\u3059\u5f71\u97ff\u3092\u691c\u8a3c\u3059\u308b\u3053\u3068\u3068\u3057\u305f\u3002\u3002<\/p>\n

\u3010\u30ec\u30d3\u30e5\u30fc\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u306e\u7279\u6027\u3011
\n\u5065\u5e38\u6210\u4eba\u7537\u5973\u3092\u5bfe\u8c61\u3068\u3057\u3001\u30a8\u30e9\u30b0\u9178\u306e\u7d4c\u53e3\u6442\u53d6\u306b\u3088\u308b\u4f53\u91cd\u3084\u4f53\u8102\u80aa\u306b\u5bfe\u3059\u308b\u5f71\u97ff\u3092\u8abf\u3079\u305f\u67fb\u8aad\u4ed8\u304d\u8ad6\u6587\u3092\u8a55\u4fa1\u5bfe\u8c61\u3068\u3057\u305f\u3002<\/p>\n

\u3010\u4e3b\u306a\u7d50\u679c\u3011
\n4\u7a2e\u306e\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u3092\u7db2\u7f85\u7684\u306b\u8abf\u67fb\u3057\u305f\u7d50\u679c\u3001\u6700\u7d42\u7684\u306b\u7121\u4f5c\u70ba\u5316\u4e8c\u91cd\u76f2\u691c\u30d7\u30e9\u30bb\u30dc\u5bfe\u7167\u4e26\u884c\u7fa4\u9593\u6bd4\u8f03\u8a66\u9a13\u306e\u8cea\u306e\u9ad8\u3044\u8ad6\u65872\u5831\u3092\u63a1\u629e\u3057\u305f\u3002PICO\u306b\u3082\u3068\u3065\u3044\u305f\u30ea\u30b5\u30fc\u30c1\u306b\u304a\u3044\u3066\u3001\u3059\u3079\u3066\u306e\u7814\u7a76\u3067\u30a8\u30e9\u30b0\u9178\u306e\u4ecb\u5165\uff083mg\uff5e47\u338e\uff09\u306b\u3088\u3063\u3066\u5bfe\u7167\u7fa4\u3068\u6bd4\u8f03\u3057\u3066\u6709\u610f\u306b\u4f53\u91cd\u3084\u4f53\u8102\u80aa\u3092\u4f4e\u4e0b\u3059\u308b\u52b9\u679c\u306b\u80af\u5b9a\u7684\u306a\u7d50\u679c\u304c\u78ba\u8a8d\u3055\u308c\u305f\u3002\u65e5\u672c\u306e\u5065\u5e38\u6210\u4eba\u7537\u5973\u3092\u5bfe\u8c61\u3068\u3057\u3066\u3044\u305f\u3002\u672c\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\u306e\u7d50\u679c\u3001\u30a8\u30e9\u30b0\u91783mg\uff5e47\u338e\u3092\u7d4c\u53e3\u6442\u53d6\u3059\u308b\u3053\u3068\u3067\u3001\u5065\u5e38\u8005\u306b\u5bfe\u3057\u3066\u4f53\u8102\u80aa\u3001\u8840\u4e2d\u4e2d\u6027\u8102\u80aa\u3001\u4f53\u91cd\u3001\u30a6\u30a8\u30b9\u30c8\u5468\u56f2\u5f84\u3001\u5185\u81d3\u8102\u80aa\u306e\u6e1b\u5c11\u3092\u30b5\u30dd\u30fc\u30c8\u3057\u3001\u9ad8\u3081\u306eBMI\u5024\u306e\u6539\u5584\u306b\u5f79\u7acb\u3064\u52b9\u679c\u304c\u8a8d\u3081\u3089\u308c\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u305f\u3002\u5c4a\u51fa\u88fd\u54c1\u306e\u30a8\u30e9\u30b0\u9178\u306e\u4e00\u65e5\u6442\u53d6\u76ee\u5b89\u91cf\u306f3mg\u3067\u3042\u308a\u3001\u3053\u306e\u4ecb\u5165\u91cf\u306f\u672c\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\u306e\u4ecb\u5165\u91cf\u3068\u4e00\u81f4\u3059\u308b\u3002<\/p>\n

\u3010\u79d1\u5b66\u7684\u6839\u62e0\u306e\u8cea\u3011
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