{"id":38474,"date":"2025-10-17T07:10:10","date_gmt":"2025-10-16T22:10:10","guid":{"rendered":"https:\/\/yakujihou-marketing.net\/database\/?p=38474"},"modified":"2026-02-06T02:46:46","modified_gmt":"2026-02-05T17:46:46","slug":"k443","status":"publish","type":"post","link":"https:\/\/yakujihou-marketing.net\/database\/k443\/","title":{"rendered":"\u8102\u80aa\u5bfe\u7b56\u30ca\u30c3\u30c4 \u30a2\u30fc\u30e2\u30f3\u30c9(K443)"},"content":{"rendered":"\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
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\u6d88\u8cbb\u8005\u5e81URL<\/td>\nhttps:\/\/www.fld.caa.go.jp\/caaks\/s\/cssc01\/fwccd01?c__id=a09RA00000HoeWkYAJ<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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\n\u300c\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u30b0\u30ed\u30d3\u30f3\u7531\u6765\u30d0\u30ea\u30f3-\u30d0\u30ea\u30f3-\u30c1\u30ed\u30b7\u30f3-\u30d7\u30ed\u30ea\u30f3 3mg\u306b\u3088\u308b\u98df\u5f8c\u306e\u8840\u4e2d\u4e2d\u6027\u8102\u80aa\u306e\u4e0a\u6607\u3092\u6291\u3048\u308b\u6a5f\u80fd\u6027\u306b\u95a2\u3059\u308b\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\u300d\u66f4\u65b0\u7248\uff08PRISMA2020\u6e96\u62e0\uff09<\/p>\n

\u3010\u76ee\u7684\u3011
\n\u30ea\u30b5\u30fc\u30c1\u30af\u30a8\u30b9\u30c1\u30e7\u30f3(RQ)\u306f\u300c\u5065\u5eb7\u306a\u6210\u4eba\u7537\u5973\u306b\u304a\u3044\u3066(P)\u3001\u30b0\u30ed\u30d3\u30f3\u7531\u6765\u30d0\u30ea\u30f3-\u30d0\u30ea\u30f3-\u30c1\u30ed\u30b7\u30f3-\u30d7\u30ed\u30ea\u30f3 3mg\u3092\u8102\u80aa\u3092\u542b\u3080\u98f2\u98df\u54c1\u3068\u3068\u3082\u306b\u7d4c\u53e3\u6442\u53d6\u3059\u308b\u3053\u3068\u306b\u3088\u308a(I)\u3001\u30d7\u30e9\u30bb\u30dc\u3068\u6bd4\u8f03\u3057\u3066(C)\u3001\u98df\u5f8c\u306e\u8840\u4e2d\u4e2d\u6027\u8102\u80aa\u306e\u4e0a\u6607\u3092\u6291\u3048\u308b\u304b(O)\u300d\u3068\u3057\u3066\u3001\u672c\u30ec\u30d3\u30e5\u30fc\u3092\u5b9f\u65bd\u3057\u305f\u3002\u672c\u30ec\u30d3\u30e5\u30fc\u306f\u65e2\u5b58\u306e\u300e\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u300c\u30b0\u30ed\u30d3\u30f3\u7531\u6765\u30d0\u30ea\u30f3-\u30d0\u30ea\u30f3-\u30c1\u30ed\u30b7\u30f3-\u30d7\u30ed\u30ea\u30f3\u300d\u306b\u3088\u308b\u98df\u5f8c\u306e\u8840\u4e2d\u4e2d\u6027\u8102\u80aa\u306e\u4e0a\u6607\u6291\u5236\u4f5c\u7528\u306e\u6a5f\u80fd\u6027\u306b\u95a2\u3059\u308b\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\u300f\uff08\u5c4a\u51fa\u756a\u53f7\uff1aJ530\uff09\u306e\u66f4\u65b0\u7248\u3067\u3042\u308b\u3002<\/p>\n

\u3010\u80cc\u666f\u3011
\n\u8fd1\u5e74\u3001\u98df\u306e\u6b27\u7c73\u5316\u3068\u9ad8\u9f62\u5316\u306b\u4f34\u3044\u3001\u72ed\u5fc3\u75c7\u3084\u5fc3\u7b4b\u6897\u585e\u306a\u3069\u306e\u5fc3\u8840\u7ba1\u7cfb\u75be\u60a3\u3084\u8133\u6897\u585e\u3084\u8133\u5352\u4e2d\u306a\u3069\u306e\u8133\u8840\u7ba1\u75be\u60a3\u304c\u5897\u52a0\u3057\u3001\u65e5\u672c\u4eba\u306e\u6b7b\u56e0\u306e\u7d0422\uff05\u3092\u5360\u3081\u3066\u3044\u308b\u3002\u3053\u308c\u307e\u3067\u306b\u3001\u7a7a\u8179\u6642\u306e\u4e2d\u6027\u8102\u80aa\u304c\u9ad8\u3044\u307b\u3069\u51a0\u52d5\u8108\u75be\u60a3\u3084\u8133\u6897\u585e\u306a\u3069\u306e\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308b\u3053\u3068\u306f\u5206\u304b\u3063\u3066\u3044\u305f\u304c\u3001\u65b0\u305f\u306b\u7a7a\u8179\u6642\u306f\u6b63\u5e38\u3067\u3042\u3063\u3066\u3082\u3001\u98df\u5f8c\u306e\u8840\u4e2d\u4e2d\u6027\u8102\u80aa\u304c\u9ad8\u3044\u307b\u3069\u3001\u3053\u308c\u3089\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u304d\u305f\u3002\u305d\u306e\u305f\u3081\u3001\u300c\u52d5\u8108\u786c\u5316\u6027\u75be\u60a3\u4e88\u9632\u30ac\u30a4\u30c9\u30e9\u30a4\u30f32022\u5e74\u7248\u300d\u306e\u6539\u8a02\u3067\u306f\u3001\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u306e\u8102\u8cea\u7570\u5e38\u75c7\u306e\u8a3a\u65ad\u57fa\u6e96\u5024\u3068\u3057\u3066\u3001\u5f93\u6765\u306e\u7a7a\u8179\u6642\u306e\u8840\u4e2d\u4e2d\u6027\u8102\u80aa\u5024(150mg\/dL\u4ee5\u4e0a)\u306b\u52a0\u3048\u3001\u65b0\u305f\u306b\u968f\u6642(\u975e\u7a7a\u8179\u6642)\u306e\u8840\u4e2d\u4e2d\u6027\u8102\u80aa\u5024(175mg\/dL\u4ee5\u4e0a)\u304c\u8a2d\u5b9a\u3055\u308c\u305f\u3002\u3053\u308c\u3089\u306e\u3053\u3068\u304b\u3089\u3001\u7a7a\u8179\u6642\u306e\u8840\u4e2d\u4e2d\u6027\u8102\u80aa\u304c\u6b63\u5e38\u307e\u305f\u306f\u9ad8\u5024\u306b\u95a2\u308f\u3089\u305a\u3001\u98df\u5f8c\u306e\u8840\u4e2d\u4e2d\u6027\u8102\u80aa\u306e\u4e0a\u6607\u3092\u6291\u3048\u308b\u3053\u3068\u306f\u3001\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u306e\u4f4e\u6e1b\u306b\u7e4b\u304c\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u3002<\/p>\n

\u3010\u30ec\u30d3\u30e5\u30fc\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u306e\u7279\u6027\u3011
\n\u30fb\u691c\u7d22\u65e5\uff1a2024\u5e7412\u670820\u65e5(\u82f1\u6587\u3001\u548c\u6587\u3068\u3082)
\n\u30fb\u691c\u7d22\u5bfe\u8c61\u671f\u9593\uff1a\u5404\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u958b\u8a2d\u6642\u304b\u3089\u691c\u7d22\u65e5\u307e\u3067
\n\u30fb\u5bfe\u8c61\u96c6\u56e3\u306e\u7279\u6027(\u6027\u3001\u5e74\u9f62\u3001\u5065\u5eb7\u72b6\u614b\u7b49)\uff1a\u5065\u5eb7\u306a\u6210\u4eba\u7537\u5973(\u7a7a\u8179\u6642\u8840\u4e2d\u4e2d\u6027\u8102\u80aa\u304c\u6b63\u5e38\u57df149mg\/dL\u4ee5\u4e0b)
\n\u30fb\u6700\u7d42\u7684\u306b\u8a55\u4fa1\u3057\u305f\u8ad6\u6587\u6570\uff1a\u548c\u65871\u5831
\n\u30fb\u7814\u7a76\u30c7\u30b6\u30a4\u30f3(S)\uff1a\u30d7\u30e9\u30bb\u30dc\u5bfe\u7167\u6bd4\u8f03\u8a66\u9a13(\u7121\u4f5c\u70ba\u5316\u5358\u76f2\u691c\u30d7\u30e9\u30bb\u30dc\u5bfe\u7167\u4ea4\u53c9\u6bd4\u8f03\u8a66\u9a131\u5831)
\n\u30fb\u5229\u76ca\u76f8\u53cd\u60c5\u5831\u7b49\uff1a\u672c\u30ec\u30d3\u30e5\u30fc\u306f\u30a8\u30e0\u30b8\u30fc\u30d5\u30a1\u30fc\u30de\u682a\u5f0f\u4f1a\u793e\u306e\u8cc7\u91d1\u63d0\u4f9b\u306b\u3088\u308a\u3001\u30a8\u30e0\u30b8\u30fc\u30d5\u30a1\u30fc\u30de\u682a\u5f0f\u4f1a\u793e\u306e\u5f93\u696d\u54e1\u304c\u5b9f\u65bd\u3057\u305f\u3002\u307e\u305f\u3001\u682a\u5f0f\u4f1a\u793e\u85ac\u4e8b\u6cd5\u30de\u30fc\u30b1\u2015\u30c6\u30a3\u30f3\u30b0\u4e8b\u52d9\u6240\u306b\u30ec\u30d3\u30e5\u30fc\u4f5c\u6210\u306e\u6307\u5c0e\u30fb\u76e3\u4fee\u8cbb\u7528\u3068\u3057\u3066\u8b1d\u91d1\u3092\u652f\u6255\u3063\u305f\u3002<\/p>\n

\u3010\u4e3b\u306a\u7d50\u679c\u3011
\n\u672c\u30ec\u30d3\u30e5\u30fc\u306e\u7d50\u679c\u3001PICOS\u306b\u4e00\u81f4\u3057\u305f\u8ad6\u6587\u304c1\u5831\u63a1\u7528\u3055\u308c\u305f\u3002\u63a1\u7528\u6587\u732e1\u5831\u4e2d1\u5831\u304c\u3001\u5065\u5eb7\u306a\u6210\u4eba\u7537\u5973\u304c\u3001\u30b0\u30ed\u30d3\u30f3\u7531\u6765\u30d0\u30ea\u30f3-\u30d0\u30ea\u30f3-\u30c1\u30ed\u30b7\u30f3-\u30d7\u30ed\u30ea\u30f3 3mg\u3092\u8102\u80aa\u3092\u542b\u3080\u98f2\u98df\u54c1\u3068\u3068\u3082\u306b\u7d4c\u53e3\u6442\u53d6\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u30d7\u30e9\u30bb\u30dc\u3068\u6bd4\u8f03\u3057\u3066\u3001\u98df\u5f8c\u306e\u8840\u4e2d\u4e2d\u6027\u8102\u80aa\u306e\u4e0a\u6607\u3092\u6291\u3048\u308b\u4f5c\u7528\u3092\u8a55\u4fa1\u3057\u3066\u3044\u305f\u3002\u63a1\u7528\u8ad6\u65871\u5831\u4e2d1\u5831\u304c\u4ea4\u53c9\u8a66\u9a13\u3067\u3042\u308a\u3001\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u306f\u5408\u8a086\u540d\u3067\u3042\u3063\u305f\u3002\u672c\u30ec\u30d3\u30e5\u30fc\u306e\u63a1\u7528\u8ad6\u65871\u5831\u4e2d1\u5831\u3067\u7528\u3044\u3089\u308c\u305f\u98df\u54c1\u6027\u72b6\u306f\u6e05\u6dbc\u98f2\u6599\u6c34\u3067\u3042\u308a\u3001\u8102\u80aa\u3092\u542b\u3080\u98f2\u98df\u54c1\u3068\u3068\u3082\u306b\u30b0\u30ed\u30d3\u30f3\u7531\u6765\u30d0\u30ea\u30f3-\u30d0\u30ea\u30f3-\u30c1\u30ed\u30b7\u30f3-\u30d7\u30ed\u30ea\u30f3 3mg\u3092\u5358\u56de\u6442\u53d6\u3057\u3066\u3044\u305f\u3002\u63a1\u7528\u8ad6\u65871\u5831\u4e2d1\u5831\u306b\u304a\u3044\u3066\u3001\u30b0\u30ed\u30d3\u30f3\u7531\u6765\u30d0\u30ea\u30f3-\u30d0\u30ea\u30f3-\u30c1\u30ed\u30b7\u30f3-\u30d7\u30ed\u30ea\u30f3\u306e\u4e00\u65e5\u6442\u53d6\u91cf\u306f3mg\u3067\u3042\u3063\u305f\u3002
\n\u672c\u30ec\u30d3\u30e5\u30fc\u306e\u63a1\u7528\u8ad6\u6587\u306f1\u5831\u3067\u3042\u308a\u3001\u300cCochrane Handbook for Systematic Reviews of Interventions version 6.5. Cochrane, 2024.\u300d\u3001\u300cJBI Manual for Evidence Synthesis, 2024.\u300d\u3001\u300cJonathan\u3089, 2011.\u300d\u3067\u306f\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u3092\u9069\u5207\u306b\u884c\u3046\u305f\u3081\u306b\u7814\u7a76\u6570\u306f10\u5831\u4ee5\u4e0a\u304c\u63a8\u5968\u3055\u308c\u3066\u3044\u308b\u3053\u3068\u304b\u3089\u3001\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u306b\u3088\u308b\u5b9a\u91cf\u7684\u7d71\u5408\u306f\u5b9f\u65bd\u3057\u306a\u304b\u3063\u305f\u3002\u672c\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\u3067\u306f\u5b9a\u6027\u7684\u306a\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\u3092\u5b9f\u65bd\u3057\u305f\u305f\u3081\u3001\u7814\u7a76\u7d50\u679c\u9593\u306e\u7570\u8cea\u6027\u306e\u539f\u56e0\u3092\u63a2\u7d22\u3059\u308b\u305f\u3081\u306b\u7528\u3044\u305f\u30b5\u30d6\u30b0\u30eb\u30fc\u30d7\u89e3\u6790\u3092\u5b9f\u65bd\u3057\u306a\u304b\u3063\u305f\u3002\u307e\u305f\u3001\u7d71\u5408\u7d50\u679c\u306e\u9811\u5065\u6027\u3092\u8a55\u4fa1\u3059\u308b\u305f\u3081\u306b\u5b9f\u65bd\u3059\u308b\u4e88\u5b9a\u306e\u611f\u5ea6\u5206\u6790\u3082\u5b9f\u65bd\u3057\u306a\u304b\u3063\u305f\u3002\u63a1\u7528\u8ad6\u6587\u306e\u3046\u3061\u3001\u8840\u4e2d\u4e2d\u6027\u8102\u80aa\u3067\u306f\u52b9\u679c\u3042\u308a\u3068\u5224\u65ad\u3057\u305f\u8ad6\u6587\u304c1\u5831\u4e2d1\u5831\u3067\u3042\u308a\u3001\u30d0\u30a4\u30a2\u30b9\u30ea\u30b9\u30af\u306e\u307e\u3068\u3081\u304c\u300c\u4f4e(0)\u300d\u3067\u3042\u308b\u8ad6\u6587\u304c1\u5831\u4e2d1\u5831\u3001\u975e\u76f4\u63a5\u6027\u306e\u307e\u3068\u3081\u304c\u300c\u4f4e(0)\u300d\u3067\u3042\u308b\u8ad6\u6587\u304c1\u5831\u4e2d1\u5831\u3067\u3042\u3063\u305f\u3002\u8840\u4e2d\u4e2d\u6027\u8102\u80aa\u5024\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u78ba\u5b9f\u6027\u306f\u3001\u30d0\u30a4\u30a2\u30b9\u30ea\u30b9\u30af\u3001\u975e\u76f4\u63a5\u6027\u3001\u4e0d\u7cbe\u78ba\u3001\u975e\u4e00\u8cab\u6027\u3001\u305d\u306e\u4ed6\u306e\u30d0\u30a4\u30a2\u30b9\u306e\u8a55\u4fa1\u70b9\u306e\u7dcf\u548c\u304c-5\u3067\u3042\u3063\u305f\u3053\u3068\u304b\u3089\u3001\u300c\u4e2d(B)\u300d\u3068\u8a55\u4fa1\u3057\u305f\u3002\u5065\u5eb7\u306a\u6210\u4eba\u7537\u5973\u306e\u5408\u8a086\u540d\u306b\u304a\u3044\u3066\u3001\u30b0\u30ed\u30d3\u30f3\u7531\u6765\u30d0\u30ea\u30f3-\u30d0\u30ea\u30f3-\u30c1\u30ed\u30b7\u30f3-\u30d7\u30ed\u30ea\u30f3 3mg\u3092\u8102\u80aa\u3092\u542b\u3080\u98f2\u98df\u54c1\u3068\u3068\u3082\u306b\u7d4c\u53e3\u6442\u53d6\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u30d7\u30e9\u30bb\u30dc\u3068\u6bd4\u8f03\u3057\u3066\u3001\u98df\u5f8c\u306e\u8840\u4e2d\u4e2d\u6027\u8102\u80aa\u306e\u4e0a\u6607\u3092\u6291\u3048\u308b\u4f5c\u7528\u304c\u793a\u3055\u308c\u305f\u3002<\/p>\n

\u3010\u79d1\u5b66\u7684\u6839\u62e0\u306e\u8cea\u3011
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\u5c4a\u51fa\u756a\u53f7 K443 \u5546\u54c1\u540d \u8102\u80aa\u5bfe\u7b56\u30ca\u30c3\u30c4\u3000\u30a2\u30fc\u30e2\u30f3\u30c9 \u5c4a\u51fa\u8005\u540d \u682a\u5f0f\u4f1a\u793e\u30b5\u30f3\u30d8\u30eb\u30b9 \u5c4a\u51fa\u65e5 2025\/10\/17 \u5909\u66f4\u65e5 – \u64a4\u56de\u65e5 – \u8ca9\u58f2\u4e2d \u8ca9\u58f2\u4f11\u6b62\u4e2d \u98df\u54c1\u306e\u533a\u5206 \u52a0\u5de5\u98df\u54c1(\u305d\u306e\u4ed6) \u6a5f\u80fd […]<\/p>\n","protected":false},"author":2,"featured_media":38478,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,142],"tags":[],"class_list":{"0":"post-38474","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-triglyceride","8":"category-vvtp"},"_links":{"self":[{"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/posts\/38474","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/comments?post=38474"}],"version-history":[{"count":0,"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/posts\/38474\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/media\/38478"}],"wp:attachment":[{"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/media?parent=38474"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/categories?post=38474"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/tags?post=38474"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}