{"id":38495,"date":"2025-10-17T08:20:41","date_gmt":"2025-10-16T23:20:41","guid":{"rendered":"https:\/\/yakujihou-marketing.net\/database\/?p=38495"},"modified":"2026-02-06T11:29:30","modified_gmt":"2026-02-06T02:29:30","slug":"k450","status":"publish","type":"post","link":"https:\/\/yakujihou-marketing.net\/database\/k450\/","title":{"rendered":"\u30ca\u30a4\u30b7\u30c0\u30a6\u30f3\u8840\u7cd6\u30b1\u30a2\u30d7\u30e9\u30b9(K450)"},"content":{"rendered":"\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
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\u4e00\u65e5\u5f53\u305f\u308a\u306e\u6442\u53d6\u76ee\u5b89\u91cf<\/td>\n2\u7c92<\/td>\n<\/tr>\n
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\n\u542b\u6709\u91cf\uff1a\u30d6\u30e9\u30c3\u30af\u30b8\u30f3\u30b8\u30e3\u30fc\u7531\u6765\u30dd\u30ea\u30e1\u30c8\u30ad\u30b7\u30d5\u30e9\u30dc\u30f3 12mg \u3001\u30d0\u30ca\u30d0\u8449\u7531\u6765\u30b3\u30ed\u30bd\u30ea\u30f3\u9178 0.9mg<\/td>\n<\/tr>\n
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\u6d88\u8cbb\u8005\u5e81URL<\/td>\nhttps:\/\/www.fld.caa.go.jp\/caaks\/s\/cssc01\/fwccd01?c__id=a09RA00000HoeWrYAJ<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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\n\u672c\u5c4a\u51fa\u54c1\u306b\u306f\u55ab\u98df\u5b9f\u7e3e\u304c\u306a\u3044\u305f\u3081\u3001\u672c\u5c4a\u51fa\u54c1\u3068\u985e\u4f3c\u3059\u308b\u98df\u54c1\u306a\u3089\u3073\u306b\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u306e\u55ab\u98df\u5b9f\u7e3e\u304a\u3088\u3073\u5b89\u5168\u6027\u60c5\u5831\u3092\u8abf\u67fb\u3057\u3001\u5b89\u5168\u6027\u3092\u8a55\u4fa1\u3057\u305f\u3002
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\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u540c\u58eb\u306e\u76f8\u4e92\u4f5c\u7528\u306b\u3064\u3044\u3066\u3001\u73fe\u5728\u306e\u3068\u3053\u308d\u76f8\u4e92\u4f5c\u7528\u306b\u95a2\u3059\u308b\u5831\u544a\u304c\u306a\u3044\u305f\u3081\u3001\u672c\u5c4a\u51fa\u54c1\u306e\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u540c\u58eb\u306e\u76f8\u4e92\u4f5c\u7528\u306b\u3088\u308a\u5065\u5eb7\u88ab\u5bb3\u304c\u751f\u3058\u308b\u53ef\u80fd\u6027\u306f\u300c\u306a\u3057\u300d\u3068\u8a55\u4fa1\u3059\u308b\u3002
\n\u4eca\u5f8c\u3082\u5b9a\u671f\u7684\u306b\u60c5\u5831\u3092\u53ce\u96c6\u3057\u5fc5\u8981\u306b\u5fdc\u3058\u3066\u60c5\u5831\u66f4\u65b0\u3092\u304a\u3053\u306a\u3046\u3002<\/p>\n

\u6a5f\u80fd\u6027\u306b\u95a2\u3059\u308b\u57fa\u672c\u60c5\u5831<\/h2>\n

\u6a5f\u80fd\u6027\u306e\u8a55\u4fa1\u65b9\u6cd5<\/h3>\n

\u25a0\u6700\u7d42\u88fd\u54c1\u3067\u306f\u306a\u304f\u3001\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u306b\u95a2\u3059\u308b\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\u3067\u3001\u6a5f\u80fd\u6027\u3092\u8a55\u4fa1\u3057\u3066\u3044\u308b\u3002<\/p>\n

\u5f53\u8a72\u88fd\u54c1\u306e\u6a5f\u80fd\u6027\u306b\u95a2\u3059\u308b\u5c4a\u51fa\u8005\u306e\u8a55\u4fa1<\/h3>\n

\uff1c\u30d6\u30e9\u30c3\u30af\u30b8\u30f3\u30b8\u30e3\u30fc\u7531\u6765\u30dd\u30ea\u30e1\u30c8\u30ad\u30b7\u30d5\u30e9\u30dc\u30f3\uff1e
\n\u3010\u6a19\u984c\u3011
\n\u30d6\u30e9\u30c3\u30af\u30b8\u30f3\u30b8\u30e3\u30fc\u7531\u6765\u30dd\u30ea\u30e1\u30c8\u30ad\u30b7\u30d5\u30e9\u30dc\u30f3\u6442\u53d6\u306b\u3088\u308b\u3001\u8179\u90e8\u306e\u8102\u80aa\u3092\u6e1b\u3089\u3059\u6a5f\u80fd\u306b\u95a2\u3059\u308b\u7814\u7a76
\n\u3010\u76ee\u7684\u30fb\u80cc\u666f\u3011
\nBMI\u304c\u9ad8\u3081\u306e\u5065\u5eb7\u306a\u65b9\u304c\u30d6\u30e9\u30c3\u30af\u30b8\u30f3\u30b8\u30e3\u30fc\u7531\u6765\u30dd\u30ea\u30e1\u30c8\u30ad\u30b7\u30d5\u30e9\u30dc\u30f3\u3092\u7d99\u7d9a\u6442\u53d6\u3057\u305f\u5834\u5408\u306e\u8179\u90e8\u306e\u8102\u80aa\u306b\u4e0e\u3048\u308b\u5f71\u97ff\u306b\u95a2\u3059\u308b\u6709\u52b9\u6027\u3092\u691c\u8a3c\u3057\u3066\u3044\u305f\u3002
\n\u30d6\u30e9\u30c3\u30af\u30b8\u30f3\u30b8\u30e3\u30fc\u7531\u6765\u30dd\u30ea\u30e1\u30c8\u30ad\u30b7\u30d5\u30e9\u30dc\u30f3\u306e\u8102\u80aa\u306b\u5bfe\u3059\u308b\u5f71\u97ff\u306b\u95a2\u3057\u3066\u3001in vitro\u5b9f\u9a13\u3084\u52d5\u7269\u5b9f\u9a13\u3067\u306f\u3001\u8102\u80aa\u5206\u89e3\u4fc3\u9032\u4f5c\u7528\u304c\u3042\u308b\u3068\u3044\u3046\u7814\u7a76\u5831\u544a\u304c\u3042\u308b\u3002\u3057\u304b\u3057\u3001\u30d2\u30c8\u3092\u5bfe\u8c61\u3068\u3057\u305f\u6587\u732e\u3092\u5305\u62ec\u7684\u306b\u6574\u7406\u3059\u308b\u30ec\u30d3\u30e5\u30fc\u3067\u306f\u3001\u8102\u80aa\u306b\u5bfe\u3059\u308b\u5f71\u97ff\u3092\u8a55\u4fa1\u3057\u305f\u3082\u306e\u306f\u306a\u304b\u3063\u305f\u3002\u305d\u306e\u305f\u3081\u3001\u30d6\u30e9\u30c3\u30af\u30b8\u30f3\u30b8\u30e3\u30fc\u7531\u6765\u30dd\u30ea\u30e1\u30c8\u30ad\u30b7\u30d5\u30e9\u30dc\u30f3\u6442\u53d6\u306b\u3088\u308b\u3001\u8179\u90e8\u306e\u8102\u80aa\u306b\u4e0e\u3048\u308b\u5f71\u97ff\u306b\u95a2\u3059\u308b\u672c\u30ec\u30d3\u30e5\u30fc\u3092\u8a55\u4fa1\u3057\u305f\u3002
\n\u3010\u30ec\u30d3\u30e5\u30fc\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u306e\u7279\u6027\u3011
\n\u56fd\u5185\u5916\u306e\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u3092\u4f7f\u7528\u3057\u3066\u3001\u691c\u7d22\u5bfe\u8c61\u671f\u9593\u306f\u8a2d\u3051\u305a\u306b\u691c\u7d22\uff08\u6700\u7d42\u691c\u7d22\u65e52023\u5e749\u670826\u65e5\uff09\u3057\u3001\u57fa\u6e96\u306b\u8a72\u5f53\u3057\u305f\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u306e\u7814\u7a762\u5831\u3092\u63a1\u7528\u3057\u3066\u3044\u305f\u3002\u63a1\u7528\u7814\u7a76\u306f\u3044\u305a\u308c\u3082\u300120-64\u6b73\u306e\u3001BMI\u304c\u9ad8\u3081\u306e\u5065\u5eb7\u306a\u65e5\u672c\u4eba\u6210\u4eba\u7537\u5973\u3092\u53c2\u52a0\u8005\u3068\u3057\u305f\u8a66\u9a13\u3067\u3001\u89e3\u6790\u5bfe\u8c61\u8005\u306b\u8102\u8cea\u7570\u5e38\u30fb\u9ad8\u8840\u7cd6\u30fb\u9ad8\u8840\u5727\u306b\u8a72\u5f53\u3059\u308b\u53c2\u52a0\u8005\u306f\u542b\u307e\u308c\u306a\u304b\u3063\u305f\u3002\u3044\u305a\u308c\u306e\u7814\u7a76\u3082\u4e38\u5584\u88fd\u85ac\u682a\u5f0f\u4f1a\u793e\u304c\u8cbb\u7528\u8ca0\u62c5\u3057\u305f\u7814\u7a76\u3067\u3042\u3063\u305f\u304c\u3001\u672c\u30ec\u30d3\u30e5\u30fc\u306f\u63a1\u7528\u7814\u7a76\u306e\u8ad6\u6587\u8457\u8005\u3092\u9664\u3044\u305f\u793e\u54e1\u306b\u3088\u308a\u516c\u6b63\u306b\u5b9f\u65bd\u3055\u308c\u3066\u3044\u305f\u3002
\n\u3010\u4e3b\u306a\u7d50\u679c\u3011
\n\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u306e\u7d50\u679c\u3001\u30d6\u30e9\u30c3\u30af\u30b8\u30f3\u30b8\u30e3\u30fc\u7531\u6765\u30dd\u30ea\u30e1\u30c8\u30ad\u30b7\u30d5\u30e9\u30dc\u30f3\u6442\u53d6\u3067\u3001\u8179\u90e8\u5185\u81d3\u8102\u80aa\u9762\u7a4d\u306b\u5bfe\u3059\u308b\u6a19\u6e96\u5316\u5e73\u5747\u5024\u5dee\uff08\u4ee5\u4e0b\u3001SMD\uff09\u3067\u306e\u52b9\u679c\u63a8\u5b9a\u5024\u306895%CI\u306f-0.57\u3014-0.92, -0.21\u3015\u3001I\u7d71\u8a08\u91cf\u306fI2=0%\u3001\u8179\u90e8\u7dcf\u8102\u80aa\u9762\u7a4d\u306b\u5bfe\u3057\u3066\u306f-0.49\u3014-0.84, -0.14\u3015\u3001I\u7d71\u8a08\u91cf\u306fI2=0%\u3067\u3042\u3063\u305f\u3002\u63a1\u7528\u7814\u7a762\u5831\u306e\u5168\u53c2\u52a0\u8005\u306b\u6709\u5bb3\u4e8b\u8c61\u306e\u5831\u544a\u306f\u306a\u304b\u3063\u305f\u3002\u305d\u306e\u305f\u3081\u3001\u30d6\u30e9\u30c3\u30af\u30b8\u30f3\u30b8\u30e3\u30fc\u7531\u6765\u30dd\u30ea\u30e1\u30c8\u30ad\u30b7\u30d5\u30e9\u30dc\u30f3\u306e\u6442\u53d6\u306f\u3001\u6709\u5bb3\u4e8b\u8c61\u3092\u793a\u3059\u3053\u3068\u306a\u304f\u6a5f\u80fd\u6027\uff08\u8179\u90e8\u306e\u8102\u80aa\uff08\u5185\u81d3\u8102\u80aa\u3001\u8179\u90e8\u7dcf\u8102\u80aa\uff09\u306e\u6e1b\u5c11\uff09\u304c\u671f\u5f85\u3067\u304d\u308b\u3002
\n\u3010\u79d1\u5b66\u7684\u6839\u62e0\u306e\u8cea\u3011
\n\u30d0\u30a4\u30a2\u30b9\u30ea\u30b9\u30af\u3001\u975e\u76f4\u63a5\u6027\u3001\u975e\u4e00\u8cab\u6027\u53ca\u3073\u4e0d\u7cbe\u78ba\u306f\u4f4e\u3001\u305d\u306e\u4ed6\uff08\u51fa\u7248\u30d0\u30a4\u30a2\u30b9\u306a\u3069\uff09\u306f\u4e2d\u306e\u305f\u3081\u3001\u30a8\u30d3\u30c7\u30f3\u30b9\u7dcf\u4f53\u306e\u548c\u306f-1\u3067\u3042\u3063\u305f\u3002\u9650\u754c\u3068\u3057\u3066\u3001\u63a1\u7528\u7814\u7a76\u304c2\u5831\u3067\u51fa\u7248\u30d0\u30a4\u30a2\u30b9\u304c\u5426\u5b9a\u3067\u304d\u306a\u304b\u3063\u305f\u3053\u3068\u304c\u6319\u3052\u3089\u308c\u308b\u304c\u3001\u7814\u7a76\u306f\u80af\u5b9a\u7684\u306a\u5185\u5bb9\u3067\u3042\u308a\u3001\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u78ba\u5b9f\u6027\u306f\u300c\u9ad8\uff08A\uff09\u300d\u3068\u8a55\u4fa1\u3055\u308c\u3066\u304a\u308a\u3001\u8179\u90e8\u306e\u8102\u80aa\u3092\u6e1b\u3089\u3059\u6a5f\u80fd\u306b\u3064\u3044\u3066\u3001\u80af\u5b9a\u7684\u306a\u7d50\u679c\u3067\u3042\u308b\u3068\u8a55\u4fa1\u3057\u305f\u3002<\/p>\n

\u3010\u6a19\u984c\u3011
\n\u30d6\u30e9\u30c3\u30af\u30b8\u30f3\u30b8\u30e3\u30fc\u7531\u6765\u30dd\u30ea\u30e1\u30c8\u30ad\u30b7\u30d5\u30e9\u30dc\u30f3\u6442\u53d6\u304c\u65e5\u5e38\u6d3b\u52d5\u6642\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u4ee3\u8b1d\u306b\u304a\u3044\u3066\u3001\u8102\u80aa\u3092\u6d88\u8cbb\u3057\u3084\u3059\u304f\u3059\u308b\u6a5f\u80fd\u306b\u95a2\u3059\u308b\u7814\u7a76
\n\u3010\u76ee\u7684\u30fb\u80cc\u666f\u3011
\n\u30d6\u30e9\u30c3\u30af\u30b8\u30f3\u30b8\u30e3\u30fc\u7531\u6765\u30dd\u30ea\u30e1\u30c8\u30ad\u30b7\u30d5\u30e9\u30dc\u30f3\u6442\u53d6\u306b\u3088\u308b\u65e5\u5e38\u6d3b\u52d5\u6642\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u4ee3\u8b1d\u306b\u304a\u3044\u3066\u3001\u8102\u80aa\u3092\u6d88\u8cbb\u3057\u3084\u3059\u304f\u3059\u308b\u6a5f\u80fd\u306b\u95a2\u3059\u308b\u6709\u52b9\u6027\u3092\u691c\u8a3c\u3059\u308b\u3053\u3068\u3092\u76ee\u7684\u3068\u3057\u3066\u3044\u305f\u3002
\n\u80a5\u6e80\u3092\u4f4e\u6e1b\u3059\u308b\u3053\u3068\u306f\u91cd\u8981\u306a\u8ab2\u984c\u3067\u3042\u308a\u3001\u80a5\u6e80\u4f4e\u6e1b\u306b\u306f\u4ee3\u8b1d\u6a5f\u80fd\u3092\u6539\u5584\u3057\u3001\u4f53\u8102\u80aa\u3092\u6d88\u8cbb\u3059\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3042\u308a\u3001\u65e5\u5e38\u6d3b\u52d5\u6642\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u4ee3\u8b1d\u306b\u304a\u3044\u3066\u3001\u8102\u80aa\u3092\u6d88\u8cbb\u3057\u3084\u3059\u304f\u3059\u308b\u3053\u3068\u306f\u80a5\u6e80\u306e\u4e88\u9632\u306b\u5f79\u7acb\u3064\u3068\u8003\u3048\u3089\u308c\u308b\u3002\u305d\u3053\u3067\u3001\u30d6\u30e9\u30c3\u30af\u30b8\u30f3\u30b8\u30e3\u30fc\u7531\u6765\u30dd\u30ea\u30e1\u30c8\u30ad\u30b7\u30d5\u30e9\u30dc\u30f3\u306e\u65e5\u5e38\u6d3b\u52d5\u6642\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u4ee3\u8b1d\u306b\u304a\u3051\u308b\u8102\u80aa\u6d88\u8cbb\u306b\u95a2\u3059\u308b\u672c\u30ec\u30d3\u30e5\u30fc\u3092\u8a55\u4fa1\u3057\u305f\u3002
\n\u3010\u30ec\u30d3\u30e5\u30fc\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u306e\u7279\u6027\u3011
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\n\u3010\u4e3b\u306a\u7d50\u679c\u3011
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\n\u3010\u79d1\u5b66\u7684\u6839\u62e0\u306e\u8cea\u3011
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