{"id":38607,"date":"2025-10-23T08:30:17","date_gmt":"2025-10-22T23:30:17","guid":{"rendered":"https:\/\/yakujihou-marketing.net\/database\/?p=38607"},"modified":"2026-02-16T02:00:45","modified_gmt":"2026-02-15T17:00:45","slug":"k486","status":"publish","type":"post","link":"https:\/\/yakujihou-marketing.net\/database\/k486\/","title":{"rendered":"\uff22\uff49\uff46\uff49\uff38\uff08\u30d3\u30d5\u30a3\u30c3\u30af\u30b9\uff09\u30e8\u30fc\u30b0\u30eb\u30c8\u03b1 \u30c9\u30ea\u30f3\u30af\u30bf\u30a4\u30d7 \u3084\u3055\u3057\u3044\u7518\u3055\uff1c\u4f4e\u8102\u80aa\uff1e\uff45(K486)"},"content":{"rendered":"\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\u5c4a\u51fa\u756a\u53f7<\/td>\nK486<\/td>\n<\/tr>\n
\u5546\u54c1\u540d<\/td>\n\uff22\uff49\uff46\uff49\uff38\uff08\u30d3\u30d5\u30a3\u30c3\u30af\u30b9\uff09\u30e8\u30fc\u30b0\u30eb\u30c8\u03b1\u3000\u30c9\u30ea\u30f3\u30af\u30bf\u30a4\u30d7\u3000\u3084\u3055\u3057\u3044\u7518\u3055\uff1c\u4f4e\u8102\u80aa\uff1e\uff45<\/td>\n<\/tr>\n
\u5c4a\u51fa\u8005\u540d<\/td>\n\u6c5f\u5d0e\u30b0\u30ea\u30b3\u682a\u5f0f\u4f1a\u793e<\/td>\n<\/tr>\n
\u5c4a\u51fa\u65e5<\/td>\n2025\/10\/23<\/td>\n<\/tr>\n
\u5909\u66f4\u65e5<\/td>\n–<\/td>\n<\/tr>\n
\u64a4\u56de\u65e5<\/td>\n–<\/td>\n<\/tr>\n
\u8ca9\u58f2\u4e2d<\/td>\n\u8ca9\u58f2\u4f11\u6b62\u4e2d<\/td>\n<\/tr>\n
\u98df\u54c1\u306e\u533a\u5206<\/td>\n\u52a0\u5de5\u98df\u54c1(\u305d\u306e\u4ed6)<\/td>\n<\/tr>\n
\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u540d<\/td>\n\u30d3\u30d5\u30a3\u30ba\u30b9\u83ccBifiX (B. lactis GCL2505)\u3001 \u30a4\u30cc\u30ea\u30f3 (\u98df\u7269\u7e4a\u7dad)<\/td>\n<\/tr>\n
\u8868\u793a\u3057\u3088\u3046\u3068\u3059\u308b\u6a5f\u80fd\u6027<\/td>\n\u672c\u54c1\u306b\u306f\u30d3\u30d5\u30a3\u30ba\u30b9\u83ccBifiX\uff08B. lactis GCL2505\uff09\u3068\u30a4\u30cc\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u304c\u542b\u307e\u308c\u307e\u3059\u3002\u30d3\u30d5\u30a3\u30ba\u30b9\u83ccBifiX\u3068\u30a4\u30cc\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u306b\u306f\u3001BMI\u304c\u9ad8\u3081\u306e\u65b9\u306e\u65e5\u5e38\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u4ee3\u8b1d\u306e\u4e00\u90e8\u3067\u3042\u308b\u5b89\u9759\u6642\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u6d88\u8cbb\u306e\u5411\u4e0a\u3092\u30b5\u30dd\u30fc\u30c8\u3059\u308b\u6a5f\u80fd\u3001BMI\u304c\u9ad8\u3081\u306e\u65b9\u306e\u4f53\u8102\u80aa\u306e\u4f4e\u6e1b\u3092\u30b5\u30dd\u30fc\u30c8\u3059\u308b\u6a5f\u80fd\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/td>\n<\/tr>\n
\u5f53\u8a72\u88fd\u54c1\u304c\u60f3\u5b9a\u3059\u308b\u4e3b\u306a\u5bfe\u8c61\u8005<\/td>\n\u4e0b\u8a18\u306e\u3044\u305a\u308c\u304b\u306b\u5f53\u3066\u306f\u307e\u308b\u5bfe\u8c61\u8005 \u30fb\u5b89\u9759\u6642\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u6d88\u8cbb\u91cf\u304c\u6c17\u306b\u306a\u308bBMI\u304c\u9ad8\u3081\u306e\u5065\u5e38\u6210\u4eba \u30fb\u4f53\u8102\u80aa\u304c\u6c17\u306b\u306a\u308bBMI\u304c\u9ad8\u3081\u306e\u5065\u5e38\u6210\u4eba<\/td>\n<\/tr>\n
\u4e00\u65e5\u5f53\u305f\u308a\u306e\u6442\u53d6\u76ee\u5b89\u91cf<\/td>\n\uff11\u65e51\u672c\uff08100g\uff09\u3092\u76ee\u5b89\u306b\u304a\u53ec\u3057\u4e0a\u304c\u308a\u304f\u3060\u3055\u3044\u3002<\/td>\n<\/tr>\n
\u4e00\u65e5\u3042\u305f\u308a\u306e\u6442\u53d6\u76ee\u5b89\u91cf\u5f53\u305f\u308a\u306e\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u306e\u542b\u6709\u91cf<\/td>\n\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u540d\uff1a\u30d3\u30d5\u30a3\u30ba\u30b9\u83ccBifiX\uff08B. lactis GCL2505\uff09\u3001\u30a4\u30cc\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09
\n\u542b\u6709\u91cf\uff1a\u30d3\u30d5\u30a3\u30ba\u30b9\u83ccBifiX\uff08B. lactis GCL2505\uff09100\u5104\u500b\u3001\u30a4\u30cc\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff095.0g<\/td>\n<\/tr>\n
\u4fdd\u5b58\u306e\u65b9\u6cd5<\/td>\n\u8981\u51b7\u853510\u2103\u4ee5\u4e0b<\/td>\n<\/tr>\n
\u6442\u53d6\u306e\u65b9\u6cd5<\/td>\n\uff11\u65e51\u672c\uff08100g\uff09\u3092\u76ee\u5b89\u306b\u304a\u53ec\u3057\u4e0a\u304c\u308a\u304f\u3060\u3055\u3044\u3002<\/td>\n<\/tr>\n
\u6442\u53d6\u3092\u3059\u308b\u4e0a\u3067\u306e\u6ce8\u610f\u4e8b\u9805<\/td>\n\u672c\u54c1\u306f\u591a\u91cf\u6442\u53d6\u306b\u3088\u308a\u75be\u75c5\u304c\u6cbb\u7652\u3057\u305f\u308a\u3001\u3088\u308a\u5065\u5eb7\u304c\u5897\u9032\u3059\u308b\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/td>\n<\/tr>\n
\u8abf\u7406\u53c8\u306f\u4fdd\u5b58\u306e\u65b9\u6cd5\u306b\u95a2\u3057\u7279\u306b\u6ce8\u610f\u3092\u5fc5\u8981\u3068\u3059\u308b\u3082\u306e\u306b\u3042\u3063\u3066\u306f\u5f53\u8a72\u6ce8\u610f\u4e8b\u9805<\/td>\n\u7121<\/td>\n<\/tr>\n
\u6d88\u8cbb\u8005\u5e81URL<\/td>\nhttps:\/\/www.fld.caa.go.jp\/caaks\/s\/cssc01\/fwccd01?c__id=a09RA00000HxS8MYAV<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u5b89\u5168\u6027\u306b\u95a2\u3059\u308b\u57fa\u672c\u60c5\u5831<\/h2>\n

\u5b89\u5168\u6027\u306e\u8a55\u4fa1\u65b9\u6cd5<\/h3>\n

\u25a0\u65e2\u5b58\u60c5\u5831\u306b\u3088\u308b\u5b89\u5168\u6027\u8a66\u9a13\u7d50\u679c\u306e\u8a55\u4fa1\u306b\u3088\u308a\u3001\u5341\u5206\u306a\u5b89\u5168\u6027\u3092\u78ba\u8a8d\u3057\u3066\u3044\u308b\u3002<\/p>\n

\u5f53\u8a72\u88fd\u54c1\u306e\u5b89\u5168\u6027\u306b\u95a2\u3059\u308b\u5c4a\u51fa\u8005\u306e\u8a55\u4fa1<\/h3>\n

\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u3067\u3042\u308b\u30d3\u30d5\u30a3\u30ba\u30b9\u83ccBifiX\uff08B. lactis GCL2505\uff09\u3001\u30a4\u30cc\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u3092\u542b\u3080\u985e\u4f3c\u98df\u54c1\u306e2021\u5e741\u6708\uff5e2023\u5e7412\u6708\u306e\u55ab\u98df\u6570\u306f\u304a\u3088\u305d2100\u4e07\u98df\u3067\u3042\u308a\u3001\u91cd\u7be4\u306a\u5065\u5eb7\u88ab\u5bb3\u306f\u767a\u751f\u3057\u3066\u3044\u306a\u3044\u3002
\n\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u5358\u72ec\u3067\u306e\u55ab\u98df\u5b9f\u7e3e\u306b\u3064\u3044\u3066\u3001\u30d3\u30d5\u30a3\u30ba\u30b9\u83ccBifiX\uff08B. lactis GCL2505\uff09\u304c\u914d\u5408\u3055\u308c\u305f\u98df\u54c1\u306f2008\u5e7410\u6708\u306b\u767a\u58f2\u3055\u308c\u3066\u4ee5\u6765\u91cd\u7be4\u306a\u5065\u5eb7\u88ab\u5bb3\u306f\u767a\u751f\u3057\u3066\u3044\u306a\u3044\u3002\u307e\u305f\u3001\u30a4\u30cc\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u3092\u542b\u3080\u539f\u6599\u306f1996\u5e74\u304b\u3089\u8ca9\u58f2\u3055\u308c\u3066\u304a\u308a\u3001\u5f53\u8a72\u98df\u54c1\u306b\u542b\u307e\u308c\u308b\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u3068\u540c\u7b49\u306e\u30a4\u30cc\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u306f\u3001\u5168\u4e16\u754c\u306e\u88fd\u9020\u8ca9\u58f2\u304c100\u4e07\u30c8\u30f3\u306b\u9054\u3059\u308b\u304c\u3001\u5065\u5eb7\u88ab\u5bb3\u306f\u5831\u544a\u3055\u308c\u3066\u3044\u306a\u3044\u3002
\n\u65e2\u5b58\u60c5\u5831\u3092\u7528\u3044\u305f\u8a55\u4fa1\u306b\u3064\u3044\u3066\u3001\u6b27\u5dde\u98df\u54c1\u5b89\u5168\u6a5f\u95a2\uff08EFSA\uff09\u304c\u516c\u8868\u3057\u3066\u3044\u308b\u7279\u5b9a\u5fae\u751f\u7269\u306e\u5b89\u5168\u6027\u63a8\u5b9a\uff08Qualified Presumption of Safety:QPS\uff09\u306b\u304a\u3044\u3066\u3001\u5f53\u8a72\u88fd\u54c1\u306e\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u3067\u3042\u308b\u30d3\u30d5\u30a3\u30ba\u30b9\u83ccBifiX\uff08B. lactis GCL2505\uff09\u304c\u5c5e\u3059\u308bBifidobacterium animalis subsp. lactis\u306f\u3001\u4e3b\u306b\u30e8\u30fc\u30b0\u30eb\u30c8\u3084\u767a\u9175\u4e73\u98f2\u6599\u7b49\u306e\u4e73\u88fd\u54c1\u306b\u4f7f\u7528\u3055\u308c\u3066\u304d\u305f\u9577\u3044\u98df\u7d4c\u9a13\u306e\u6b74\u53f2\u3092\u6709\u3057\u3066\u304a\u308a\u3001\u3053\u308c\u307e\u3067\u306b\u5b89\u5168\u4e0a\u306e\u61f8\u5ff5\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u306a\u3044\u83cc\u7a2e\u3067\u3042\u308b\u3068\u3055\u308c\u3066\u3044\u308b\u3002\u307e\u305f\u3001\u7c73\u56fd\u533b\u85ac\u54c1\u98df\u54c1\u5c40\uff08FDA\uff09\u306eGRAS \u8a8d\u8a3c\u63d0\u51fa\u66f8\u985e\u306e\u4e2d\u3067\u3001\u30a4\u30cc\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u306e\u30d2\u30c8\u8a66\u9a13\u306e\u7d50\u679c\u3001\u5065\u5e38\u6210\u4eba\u306b\u304a\u3044\u3066 40\uff5e70g\/\u65e5\u306e\u30a4\u30cc\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u6442\u53d6\u3067\u306f\u5065\u5eb7\u88ab\u5bb3\u306f\u751f\u3058\u306a\u304b\u3063\u305f\u3068\u7d50\u8ad6\u4ed8\u3051\u3089\u308c\u3066\u3044\u308b\u3002
\n\u533b\u85ac\u54c1\u3068\u306e\u76f8\u4e92\u4f5c\u7528\u306b\u3064\u3044\u3066\u3001\u7c73\u56fd\u533b\u85ac\u54c1\u98df\u54c1\u5c40\uff08FDA\uff09\u306eGRAS \u8a8d\u8a3c\u63d0\u51fa\u66f8\u985e\u306e\u4e2d\u3067\u3001\u30a4\u30cc\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u304c\u30ab\u30eb\u30b7\u30a6\u30e0\u306a\u3069\u306e\u30df\u30cd\u30e9\u30eb\u306e\u5438\u53ce\u3092\u4fc3\u9032\u3059\u308b\u52b9\u679c\u306b\u3064\u3044\u3066\u8a18\u8f09\u3055\u308c\u3066\u3044\u308b\u3002\u305f\u3060\u3057\u3001\u300c\u65e5\u672c\u4eba\u306e\u98df\u4e8b\u6442\u53d6\u57fa\u6e96\u300d\uff082020\u5e74\u7248\uff09\u306e\u30ab\u30eb\u30b7\u30a6\u30e0\u3084\u30de\u30b0\u30cd\u30b7\u30a6\u30e0\u306e\u6442\u53d6\u63a8\u5968\u91cf\u3001\u8010\u5bb9\u4e0a\u9650\u91cf\u304b\u3089\u5224\u65ad\u3057\u3001\u30a4\u30cc\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u3068\u30ab\u30eb\u30b7\u30a6\u30e0\u3084\u30de\u30b0\u30cd\u30b7\u30a6\u30e0\u3068\u3044\u3063\u305f\u30df\u30cd\u30e9\u30eb\u306e\u540c\u6642\u6442\u53d6\u306b\u3088\u3063\u3066\u3001\u30ab\u30eb\u30b7\u30a6\u30e0\u3084\u30de\u30b0\u30cd\u30b7\u30a6\u30e0\u306e\u904e\u5270\u6442\u53d6\u306b\u81f3\u308b\u53ef\u80fd\u6027\u306f\u6975\u3081\u3066\u4f4e\u3044\u3068\u7d50\u8ad6\u4ed8\u3051\u305f\u3002
\n\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u540c\u58eb\u306e\u76f8\u4e92\u4f5c\u7528\u306b\u95a2\u3059\u308b\u60c5\u5831\u306f\u8a8d\u3081\u3089\u308c\u306a\u304b\u3063\u305f\u3002
\n\u4ee5\u4e0a\u3088\u308a\u3001\u5f53\u8a72\u88fd\u54c1\u3092\u6a5f\u80fd\u6027\u8868\u793a\u98df\u54c1\u3068\u3057\u3066\u8ca9\u58f2\u3059\u308b\u3053\u3068\u306f\u9069\u5207\u3067\u3042\u308b\u3068\u5224\u65ad\u3057\u305f\u3002<\/p>\n

\u6a5f\u80fd\u6027\u306b\u95a2\u3059\u308b\u57fa\u672c\u60c5\u5831<\/h2>\n

\u6a5f\u80fd\u6027\u306e\u8a55\u4fa1\u65b9\u6cd5<\/h3>\n

\u25a0\u6700\u7d42\u88fd\u54c1\u3067\u306f\u306a\u304f\u3001\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u306b\u95a2\u3059\u308b\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\u3067\u3001\u6a5f\u80fd\u6027\u3092\u8a55\u4fa1\u3057\u3066\u3044\u308b\u3002<\/p>\n

\u5f53\u8a72\u88fd\u54c1\u306e\u6a5f\u80fd\u6027\u306b\u95a2\u3059\u308b\u5c4a\u51fa\u8005\u306e\u8a55\u4fa1<\/h3>\n

1\uff09\u5b89\u9759\u6642\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u6d88\u8cbb\u91cf\u306e\u5411\u4e0a
\n\u6a19\u984c
\n\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u30d3\u30d5\u30a3\u30ba\u30b9\u83ccBifiX\uff08B. lactis GCL2505\uff09\u3068\u30a4\u30cc\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u306b\u3088\u308b\u3001\u5b89\u9759\u6642\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u6d88\u8cbb\u306e\u5411\u4e0a\u306e\u6a5f\u80fd\u6027\u306b\u95a2\u3059\u308b\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc<\/p>\n

\u76ee\u7684
\n\u300c\u75be\u75c5\u306b\u7f79\u60a3\u3057\u3066\u3044\u306a\u3044BMI\u304c\u9ad8\u3081\uff08BMI\u304c25 kg\/m2\u4ee5\u4e0a30 kg\/m2\u672a\u6e80\uff09\u306e\u8005\uff08\u672a\u6210\u5e74\u8005\u3001\u598a\u7523\u5a66\u3001\u6388\u4e73\u5a66\u306f\u9664\u304f\uff09\u306b\u300d\uff08P\uff09\u3001\u300c\u30d3\u30d5\u30a3\u30ba\u30b9\u83ccBifiX\uff08B. lactis GCL2505\uff09\u3068\u30a4\u30cc\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u3092\u7d99\u7d9a\u6442\u53d6\u3055\u305b\u308b\u3068\u300d\uff08I\uff09\u3001\u300c\u30d7\u30e9\u30bb\u30dc\uff08\u30d3\u30d5\u30a3\u30ba\u30b9\u83ccBifiX\uff08B. lactis GCL2505\uff09\u3068\u30a4\u30cc\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u3092\u542b\u6709\u3057\u306a\u3044\uff09\u306e\u7d99\u7d9a\u6442\u53d6\u3068\u6bd4\u8f03\u3057\u3066\u300d\uff08C\uff09\u3001\u300c\u5b89\u9759\u6642\u30a8\u30cd\u30eb\u30ae\u30fc\u6d88\u8cbb\u91cf\u300d\uff08O\uff09\u3078\u306e\u5f71\u97ff\u306e\u691c\u8a3c\u3092\u76ee\u7684\u3068\u3057\u305f\u3002<\/p>\n

\u80cc\u666f
\n\u30d3\u30d5\u30a3\u30ba\u30b9\u83ccBifiX\uff08B. lactis GCL2505\uff09\u306f\u751f\u304d\u3066\u8178\u307e\u3067\u5230\u9054\u3057\u3001\u8178\u7ba1\u5185\u3067\u5897\u6b96\u3059\u308b\u30d3\u30d5\u30a3\u30ba\u30b9\u83cc\u3067\u3001\u30a4\u30cc\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u3068\u306e\u7d44\u307f\u5408\u308f\u305b\u3067\u3001\u8178\u7ba1\u5185\u306e\u77ed\u9396\u8102\u80aa\u9178\u3092\u5897\u52a0\u3055\u305b\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3002\u52d5\u7269\u5b9f\u9a13\u306b\u3088\u3063\u3066\u77ed\u9396\u8102\u80aa\u9178\u304c\u5b89\u9759\u6642\u30a8\u30cd\u30eb\u30ae\u30fc\u6d88\u8cbb\u91cf\u3092\u5897\u52a0\u3055\u305b\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u304a\u308a\u3001\u30d2\u30c8\u306b\u304a\u3044\u3066\u3082\u30d3\u30d5\u30a3\u30ba\u30b9\u83ccBifiX\uff08B. lactis GCL2505\uff09\u3068\u30a4\u30cc\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u306f\u5b89\u9759\u6642\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u6d88\u8cbb\u91cf\u3092\u5411\u4e0a\u3055\u305b\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3002\u3057\u304b\u3057\u3001\u30d3\u30d5\u30a3\u30ba\u30b9\u83ccBifiX\uff08B. lactis GCL2505\uff09\u304a\u3088\u3073\u30a4\u30cc\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u3092\u6442\u53d6\u306b\u3088\u308b\u5b89\u9759\u6642\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u6d88\u8cbb\u306e\u5411\u4e0a\u52b9\u679c\u306b\u3064\u3044\u3066\u7db2\u7f85\u7684\u306b\u691c\u8a0e\u3057\u305fSR\u306f\u5831\u544a\u3055\u308c\u3066\u3044\u306a\u304b\u3063\u305f\u3002\u305d\u306e\u305f\u3081\u3001\u672cSR\u3092\u5b9f\u65bd\u3057\u305f\u3002<\/p>\n

\u30ec\u30d3\u30e5\u30fc\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u306e\u7279\u6027
\n7\u3064\u306e\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u304b\u3089\u30d3\u30d5\u30a3\u30ba\u30b9\u83ccBifiX\uff08B. lactis GCL2505\uff09\u304a\u3088\u3073\u30a4\u30cc\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u306b\u95a2\u3059\u308b\u82f1\u8a9e\u6587\u732e\u3001\u65e5\u672c\u8a9e\u6587\u732e\u3092\u691c\u7d22\u3057\u305f\u3002\u958b\u8a2d\u307e\u305f\u306f\u63b2\u8f09\u3055\u308c\u3066\u3044\u308b\u6700\u521d\u306e\u6642\u70b9\u304b\u3089\u691c\u7d22\u65e5\uff082025\u5e746\u670828\u65e5\uff09\u307e\u3067\u306b\u516c\u8868\u3055\u308c\u305f\u3059\u3079\u3066\u306e\u7814\u7a76\u3092\u691c\u7d22\u5bfe\u8c61\u3068\u3057\u305f\u3002\u691c\u7d22\u306e\u7d50\u679c\u3001\u5404\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u304b\u308926\u5831\u306e\u6587\u732e\u304c\u7279\u5b9a\u3055\u308c\u3001\u9069\u683c\u57fa\u6e96\u3092\u6e80\u305f\u30591\u5831\uff08\u89e3\u6790\u5bfe\u8c61\u800540\u540d\uff09\u3092\u63a1\u7528\u3057\u305f\u3002\u63a1\u7528\u3057\u305f\u7814\u7a76\u306f\u3001BMI\u304c25 kg\/m2\u4ee5\u4e0a30 kg\/m2\u672a\u6e80\u306e25\u6b73\u4ee5\u4e0a61\u6b73\u672a\u6e80\u306e\u5065\u5eb7\u306a\u7537\u5973\u306b\u3001\u30d3\u30d5\u30a3\u30ba\u30b9\u83ccBifiX\uff08B. lactis GCL2505\uff091\u00d710^10CFU\u3068\u30a4\u30cc\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff095g\u30924\u9031\u9593\u6442\u53d6\u3055\u305b\u3001\u5b89\u9759\u6642\u30a8\u30cd\u30eb\u30ae\u30fc\u6d88\u8cbb\u91cf\u3092\u8a55\u4fa1\u3057\u305f\u30e9\u30f3\u30c0\u30e0\u5316\u4e26\u884c\u7fa4\u9593\u6bd4\u8f03\u8a66\u9a13\u3067\u3042\u3063\u305f\u3002<\/p>\n

\u4e3b\u306a\u7d50\u679c
\n\u63a1\u7528\u3057\u305f\u6587\u732e\u3067\u5831\u544a\u3055\u308c\u3066\u3044\u305f\u81e8\u5e8a\u8a66\u9a13\u3067\u306f\u3001\u30d3\u30d5\u30a3\u30ba\u30b9\u83ccBifiX\uff08B. lactis GCL2505\uff091\u00d710^10CFU\u3068\u30a4\u30cc\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff095g\u3092\u542b\u6709\u3057\u305f\u4e73\u98f2\u6599\u30924\u9031\u9593\u6442\u53d6\u3055\u305b\u305f\u3002\u4ecb\u5165\u5f8c\u306e\u30d3\u30d5\u30a3\u30ba\u30b9\u83ccBifiX\uff08B. lactis GCL2505\uff09\u3068\u30a4\u30cc\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u6442\u53d6\u7fa4\u306e\u5e73\u5747\u5024\uff0895%\u4fe1\u983c\u533a\u9593\uff09\u306f1376.5 (1393.0, 1517.6) kcal\/day\u3001\u30d7\u30e9\u30bb\u30dc\u7fa4\u306e\u5e73\u5747\u5024\uff0895%\u4fe1\u983c\u533a\u9593\uff09\u306f1303.2 (1308.7, 1433.0) kcal\/day\u3067\u3001\u7fa4\u9593\u6bd4\u8f03\u306ep\u5024\u306f0.042\u3067\u3042\u308a\u3001\u6709\u610f\u306a\u5b89\u9759\u6642\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u6d88\u8cbb\u306e\u5411\u4e0a\u52b9\u679c\u3092\u6709\u3057\u3066\u3044\u305f\u3002<\/p>\n

\u79d1\u5b66\u7684\u6839\u62e0\u306e\u8cea
\n\u63a1\u7528\u3057\u305f\u7814\u7a76\u304c1\u4ef6\u306e\u307f\u3060\u3063\u305f\u305f\u3081\u3001\u30d0\u30a4\u30a2\u30b9\u30ea\u30b9\u30af\u3068\u975e\u76f4\u63a5\u6027\u306b\u3064\u3044\u3066\u306f\u3001\u7814\u7a76\u5185\u306e\u30d0\u30a4\u30a2\u30b9\u30ea\u30b9\u30af\u3068\u540c\u69d8\u306b\u305d\u308c\u305e\u308c\u4e2d(-1)\u3001\u4f4e(0)\u3068\u8a55\u4fa1\u3057\u305f\u3002\u4e0d\u7cbe\u78ba\u306b\u95a2\u3057\u3066\u306f\u3001\u89e3\u6790\u96c6\u56e3\u306e\u4f8b\u6570\u304c40\u4f8b\u3067\u3042\u308b\u305f\u3081\u3001\u4e2d(-1)\u3068\u8a55\u4fa1\u3057\u305f\u3002\u975e\u4e00\u8cab\u6027\u306b\u95a2\u3057\u3066\u306f\u3001\u63a1\u7528\u3057\u305f\u7814\u7a76\u304c\uff11\u4ef6\u306e\u307f\u3067\u3042\u308b\u305f\u3081\u3001\u9ad8(-2)\u3068\u8a55\u4fa1\u3057\u305f\u3002\u5831\u544a\u30d0\u30a4\u30a2\u30b9\u306b\u3064\u3044\u3066\u306f\u3001\u7814\u7a76\u304c\u5358\u5831\u306e\u307f\u5b58\u5728\u3057\u3001\u63a1\u7528\u8ad6\u6587\u6570\u3092\u4e0a\u56de\u308b\u672a\u5831\u544a\u7814\u7a76\u304c\u307f\u3089\u308c\u308b\u305f\u3081\u3001\u9ad8(-2)\u3068\u8a55\u4fa1\u3057\u305f\u3002\u4ee5\u4e0a\u306e\u7d50\u679c\u3001\u30a8\u30d3\u30c7\u30f3\u30b9\u7dcf\u4f53\u306e\u78ba\u5b9f\u6027\u306f\u3001RCT\u304c\u884c\u308f\u308c\u3066\u304a\u308a\u8a55\u4fa1\u5bfe\u8c61\u7814\u7a76\u81ea\u4f53\u306e\u4fe1\u983c\u6027\u306f\u4fdd\u305f\u308c\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u3082\u306e\u306e\u3001\u4e0d\u7cbe\u78ba\u3001\u975e\u4e00\u8cab\u6027\u304a\u3088\u3073\u5831\u544a\u30d0\u30a4\u30a2\u30b9\u306e\u5f71\u97ff\u304c\u5426\u5b9a\u3067\u304d\u306a\u304b\u3063\u305f\u3002\u5404\u9805\u76ee\u306e\u548c\u304c-6\u3067\u3042\u308b\u305f\u3081\u3001\u4f4e(C)\u3068\u5224\u65ad\u3057\u305f\u3002<\/p>\n

2\uff09\u5185\u81d3\u8102\u80aa\u3068\u4f53\u8102\u80aa\u306e\u6e1b\u5c11
\n\u6a19\u984c
\n\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u30d3\u30d5\u30a3\u30ba\u30b9\u83ccBifiX\uff08B. lactis GCL2505\uff09\u3068\u30a4\u30cc\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u306b\u3088\u308b\u3001\u5185\u81d3\u8102\u80aa\u3068\u4f53\u8102\u80aa\u306e\u6e1b\u5c11\u306e\u6a5f\u80fd\u6027\u306b\u95a2\u3059\u308b\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc<\/p>\n

\u76ee\u7684
\n\u300c\u75be\u75c5\u306b\u7f79\u60a3\u3057\u3066\u3044\u306a\u3044BMI\u304c\u9ad8\u3081\uff08BMI\u304c23 kg\/m2\u4ee5\u4e0a30 kg\/m2\u672a\u6e80\uff09\u306e\u8005\uff08\u672a\u6210\u5e74\u8005\u3001\u598a\u7523\u5a66\u3001\u6388\u4e73\u5a66\u306f\u9664\u304f\uff09\u306b\u300d\uff08P\uff09\u3001\u300c\u30d3\u30d5\u30a3\u30ba\u30b9\u83ccBifiX\uff08B. lactis GCL2505\uff09\u3068\u30a4\u30cc\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u3092\u7d99\u7d9a\u6442\u53d6\u3055\u305b\u308b\u3068\u300d\uff08I\uff09\u3001\u300c\u30d7\u30e9\u30bb\u30dc\uff08\u30d3\u30d5\u30a3\u30ba\u30b9\u83ccBifiX\uff08B. lactis GCL2505\uff09\u3068\u30a4\u30cc\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u3092\u542b\u6709\u3057\u306a\u3044\uff09\u306e\u7d99\u7d9a\u6442\u53d6\u3068\u6bd4\u8f03\u3057\u3066\u300d\uff08C\uff09\u3001\u300c\u5185\u81d3\u8102\u80aa\uff08\u8179\u90e8\u5185\u81d3\u8102\u80aa\u9762\u7a4d\uff09\u30fb\u4f53\u8102\u80aa\uff08\u8179\u90e8\u7dcf\u8102\u80aa\u9762\u7a4d\uff09\u300d\uff08O\uff09\u3078\u306e\u5f71\u97ff\u306e\u691c\u8a3c\u3092\u76ee\u7684\u3068\u3057\u305f\u3002<\/p>\n

\u80cc\u666f
\n\u30d3\u30d5\u30a3\u30ba\u30b9\u83ccBifiX\uff08B. lactis GCL2505\uff09\u306f\u751f\u304d\u3066\u8178\u307e\u3067\u5230\u9054\u3057\u3001\u8178\u7ba1\u5185\u3067\u5897\u6b96\u3059\u308b\u30d3\u30d5\u30a3\u30ba\u30b9\u83cc\u3067\u3001\u30a4\u30cc\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u3068\u306e\u7d44\u307f\u5408\u308f\u305b\u3067\u3001\u8178\u7ba1\u5185\u306e\u77ed\u9396\u8102\u80aa\u9178\u3092\u5897\u52a0\u3055\u305b\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3002\u52d5\u7269\u5b9f\u9a13\u306b\u3088\u3063\u3066\u30d3\u30d5\u30a3\u30ba\u30b9\u83ccBifiX\uff08B. lactis GCL2505\uff09\u3068\u30a4\u30cc\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u306e\u7d44\u5408\u305b\u304c\u3001\u77ed\u9396\u8102\u80aa\u9178\u3092\u4ecb\u3057\u3066\u4f53\u8102\u80aa\u30fb\u5185\u81d3\u8102\u80aa\u3092\u6e1b\u5c11\u3055\u305b\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u304a\u308a\u3001\u30d2\u30c8\u306b\u304a\u3044\u3066\u3082\u30d3\u30d5\u30a3\u30ba\u30b9\u83ccBifiX\uff08B. lactis GCL2505\uff09\u3068\u30a4\u30cc\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u306f\u6442\u53d6\u306b\u3088\u308a\u3001\u4f53\u8102\u80aa\u30fb\u5185\u81d3\u8102\u80aa\u3092\u6e1b\u5c11\u3055\u305b\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3002\u30d3\u30d5\u30a3\u30ba\u30b9\u83ccBifiX\uff08B. lactis GCL2505\uff09\u304a\u3088\u3073\u30a4\u30cc\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u3092\u6442\u53d6\u306b\u3088\u308b\u4f53\u8102\u80aa\u30fb\u5185\u81d3\u8102\u80aa\u306e\u6e1b\u5c11\u52b9\u679c\u3092\u7db2\u7f85\u7684\u306b\u691c\u8a0e\u3057\u305fSR\u306f\u5831\u544a\u3055\u308c\u3066\u3044\u306a\u304b\u3063\u305f\u3002\u305d\u306e\u305f\u3081\u3001\u672cSR\u3092\u5b9f\u65bd\u3057\u305f\u3002<\/p>\n

\u30ec\u30d3\u30e5\u30fc\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u306e\u7279\u6027
\n7\u3064\u306e\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u304b\u3089\u30d3\u30d5\u30a3\u30ba\u30b9\u83ccBifiX\uff08B. lactis GCL2505\uff09\u304a\u3088\u3073\u30a4\u30cc\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u306b\u95a2\u3059\u308b\u82f1\u8a9e\u6587\u732e\u3001\u65e5\u672c\u8a9e\u6587\u732e\u3092\u691c\u7d22\u3057\u305f\u3002\u958b\u8a2d\u307e\u305f\u306f\u63b2\u8f09\u3055\u308c\u3066\u3044\u308b\u6700\u521d\u306e\u6642\u70b9\u304b\u3089\u691c\u7d22\u65e5\uff082025\u5e746\u670828\u65e5\uff09\u307e\u3067\u306b\u516c\u8868\u3055\u308c\u305f\u3059\u3079\u3066\u306e\u7814\u7a76\u3092\u691c\u7d22\u5bfe\u8c61\u3068\u3057\u305f\u3002\u691c\u7d22\u306e\u7d50\u679c\u3001\u5404\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u304b\u308926\u5831\u306e\u6587\u732e\u304c\u7279\u5b9a\u3055\u308c\u3001\u9069\u683c\u57fa\u6e96\u3092\u6e80\u305f\u30591\u5831\uff08\u89e3\u6790\u5bfe\u8c61\u800540\u540d\uff09\u3092\u63a1\u7528\u3057\u305f\u3002\u63a1\u7528\u3057\u305f\u7814\u7a76\u306f\u3001BMI\u304c23 kg\/m2\u4ee5\u4e0a30 kg\/m2\u672a\u6e80\u306e20\u6b73\u4ee5\u4e0a65\u6b73\u672a\u6e80\u306e\u5065\u5eb7\u306a\u7537\u5973\u306b\u3001\u30d3\u30d5\u30a3\u30ba\u30b9\u83ccBifiX\uff08B. lactis GCL2505\uff091\u00d710^10CFU\u3068\u30a4\u30cc\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff092g\u309212\u9031\u9593\u6442\u53d6\u3055\u305b\u3001\u5185\u81d3\u8102\u80aa\uff08\u8179\u90e8\u5185\u81d3\u8102\u80aa\u9762\u7a4d\uff09\u30fb\u4f53\u8102\u80aa\uff08\u8179\u90e8\u7dcf\u8102\u80aa\u9762\u7a4d\uff09\u3092\u8a55\u4fa1\u3057\u305f\u30e9\u30f3\u30c0\u30e0\u5316\u4e26\u884c\u7fa4\u9593\u6bd4\u8f03\u8a66\u9a13\u3067\u3042\u3063\u305f\u3002<\/p>\n

\u4e3b\u306a\u7d50\u679c
\n\u63a1\u7528\u3057\u305f\u6587\u732e\u3067\u5831\u544a\u3055\u308c\u3066\u3044\u305f\u81e8\u5e8a\u8a66\u9a13\u3067\u306f\u3001\u65e5\u672c\u56fd\u7c4d\u3092\u6301\u3064\u5065\u5e38\u306a20\uff5e65\u6b73\u306e\u65b994\u540d\u3092\u5bfe\u8c61\u306b\u30d3\u30d5\u30a3\u30ba\u30b9\u83ccBifiX\uff08B. lactis GCL2505\uff09\u304a\u3088\u3073\u30a4\u30cc\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u542b\u6709\u4e73\u98f2\u6599\u309212\u9031\u9593\u6442\u53d6\u3055\u305b\u305f\u6240\u3001\u6709\u610f\u306a\u5185\u81d3\u8102\u80aa\uff08\u8179\u90e8\u5185\u81d3\u8102\u80aa\u9762\u7a4d\uff09\u3068\u4f53\u8102\u80aa\uff08\u8179\u90e8\u7dcf\u8102\u80aa\u9762\u7a4d\uff09\u306e\u6e1b\u5c11\u304c\u8a8d\u3081\u3089\u308c\u305f\u3002<\/p>\n

\u79d1\u5b66\u7684\u6839\u62e0\u306e\u8cea
\n\u63a1\u7528\u3057\u305f\u7814\u7a76\u304c1\u4ef6\u306e\u307f\u3060\u3063\u305f\u305f\u3081\u3001\u30d0\u30a4\u30a2\u30b9\u30ea\u30b9\u30af\u3068\u975e\u76f4\u63a5\u6027\u306b\u3064\u3044\u3066\u306f\u3001\u7814\u7a76\u5185\u306e\u30d0\u30a4\u30a2\u30b9\u30ea\u30b9\u30af\u3068\u540c\u69d8\u306b\u305d\u308c\u305e\u308c\u4e2d(-1)\u3001\u4f4e(0)\u3068\u8a55\u4fa1\u3057\u305f\u3002\u4e0d\u7cbe\u78ba\u306b\u95a2\u3057\u3066\u306f\u3001\u4e3b\u8981\u8a55\u4fa1\u9805\u76ee\u306e\u89e3\u6790\u96c6\u56e3\u306e\u4f8b\u6570\u304c94\u4f8b\u3067\u3042\u308b\u305f\u3081\u3001\u4e2d(-1)\u3068\u8a55\u4fa1\u3057\u305f\u3002\u975e\u4e00\u8cab\u6027\u306b\u95a2\u3057\u3066\u306f\u3001\u63a1\u7528\u3057\u305f\u7814\u7a76\u304c\uff11\u4ef6\u306e\u307f\u3067\u3042\u308b\u305f\u3081\u3001\u9ad8(-2)\u3068\u8a55\u4fa1\u3057\u305f\u3002\u5831\u544a\u30d0\u30a4\u30a2\u30b9\u306b\u3064\u3044\u3066\u306f\u3001\u7814\u7a76\u304c\u5358\u5831\u306e\u307f\u5b58\u5728\u3057\u3001\u672a\u5831\u544a\u7814\u7a76\u304c\u307f\u3089\u308c\u306a\u3044\u305f\u3081\u3001\u4e2d\/\u7591\u3044(-1)\u3068\u8a55\u4fa1\u3057\u305f\u3002\u4ee5\u4e0a\u306e\u7d50\u679c\u3001\u30a8\u30d3\u30c7\u30f3\u30b9\u7dcf\u4f53\u306e\u78ba\u5b9f\u6027\u306f\u3001RCT\u304c\u884c\u308f\u308c\u3066\u304a\u308a\u8a55\u4fa1\u5bfe\u8c61\u7814\u7a76\u81ea\u4f53\u306e\u4fe1\u983c\u6027\u306f\u4fdd\u305f\u308c\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u3082\u306e\u306e\u3001\u4e0d\u7cbe\u78ba\u3001\u975e\u4e00\u8cab\u6027\u304a\u3088\u3073\u5831\u544a\u30d0\u30a4\u30a2\u30b9\u306e\u5f71\u97ff\u304c\u5426\u5b9a\u3067\u304d\u306a\u304b\u3063\u305f\u3002\u5404\u9805\u76ee\u306e\u548c\u304c-5\u3067\u3042\u308b\u305f\u3081\u3001\u4f4e(C)\u3068\u5224\u65ad\u3057\u305f\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

\u5c4a\u51fa\u756a\u53f7 K486 \u5546\u54c1\u540d \uff22\uff49\uff46\uff49\uff38\uff08\u30d3\u30d5\u30a3\u30c3\u30af\u30b9\uff09\u30e8\u30fc\u30b0\u30eb\u30c8\u03b1\u3000\u30c9\u30ea\u30f3\u30af\u30bf\u30a4\u30d7\u3000\u3084\u3055\u3057\u3044\u7518\u3055\uff1c\u4f4e\u8102\u80aa\uff1e\uff45 \u5c4a\u51fa\u8005\u540d \u6c5f\u5d0e\u30b0\u30ea\u30b3\u682a\u5f0f\u4f1a\u793e \u5c4a\u51fa\u65e5 2025\/10\/23 \u5909\u66f4\u65e5 – \u64a4\u56de\u65e5 – \u8ca9 […]<\/p>\n","protected":false},"author":2,"featured_media":38611,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[29,8,153,32],"tags":[56],"class_list":{"0":"post-38607","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-body-fat","8":"category-bmi","9":"category-inulin","10":"category-bifidobacterium","11":"tag-yogurt"},"_links":{"self":[{"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/posts\/38607","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/comments?post=38607"}],"version-history":[{"count":0,"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/posts\/38607\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/media\/38611"}],"wp:attachment":[{"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/media?parent=38607"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/categories?post=38607"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/yakujihou-marketing.net\/database\/wp-json\/wp\/v2\/tags?post=38607"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}