{"id":39477,"date":"2025-12-10T07:40:20","date_gmt":"2025-12-09T22:40:20","guid":{"rendered":"https:\/\/yakujihou-marketing.net\/database\/?p=39477"},"modified":"2026-03-18T00:29:46","modified_gmt":"2026-03-17T15:29:46","slug":"k720","status":"publish","type":"post","link":"https:\/\/yakujihou-marketing.net\/database\/k720\/","title":{"rendered":"\u30ea\u30d5\u30a1\u30b9\u30ad\u30f3\u30a2\u30af\u30c6\u30a3\u30d6\u30d4\u30fc\u30a8\u30eb(K720)"},"content":{"rendered":"\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
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\u6d88\u8cbb\u8005\u5e81URL<\/td>\nhttps:\/\/www.fld.caa.go.jp\/caaks\/s\/cssc01\/fwccd01?c__id=a09RA00000KSHXGYA5<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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\n\u305d\u308c\u305e\u308c\u306e\u65e2\u5b58\u60c5\u5831\u3092\u8abf\u67fb\u3057\u305f\u3068\u3053\u308d\u3001\u30ed\u30c0\u30f3\u30c6\u30ce\u30f3B\u306b\u304a\u3044\u3066\u300c\u4e00\u65e5\u6442\u53d6\u76ee\u5b89\u91cf\u30928\u9031\u9593\u30d2\u30c8\u306b\u6442\u53d6\u3055\u305b\u305f\u8a66\u9a13\u300d\u304a\u3088\u3073\u300c\u4e00\u65e5\u6442\u53d6\u76ee\u5b89\u91cf\u309212\u9031\u9593\u30d2\u30c8\u306b\u6442\u53d6\u3055\u305b\u305f\u8a66\u9a13\u300d\u306a\u3089\u3073\u306b\u300c\u4e00\u65e5\u6442\u53d6\u76ee\u5b89\u91cf\u306e5\u500d\u91cf\u30924\u9031\u9593\u30d2\u30c8\u306b\u6442\u53d6\u3055\u305b\u305f\u8a66\u9a13\u300d\u304a\u3044\u3066\u3082\u3001\u6442\u53d6\u306b\u95a2\u9023\u3057\u305f\u6709\u5bb3\u4e8b\u8c61\u306f\u8a8d\u3081\u3089\u308c\u306a\u304b\u3063\u305f\u3002
\n\u308a\u3093\u3054\u7531\u6765\u30d7\u30ed\u30b7\u30a2\u30cb\u30b8\u30f3\u306b\u304a\u3044\u3066\u3001\u672c\u5c4a\u51fa\u54c1\u3068\u540c\u3058\u300c\u30a2\u30c3\u30d7\u30eb\u30d5\u30a7\u30ce\u30f3?\u300d\u3092\u4e3b\u539f\u6599\u3068\u3059\u308b\u7279\u5b9a\u4fdd\u5065\u7528\u98df\u54c1\u3068\u3057\u3066\u300c\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u8336\u300d\uff08\u308a\u3093\u3054\u7531\u6765\u30d7\u30ed\u30b7\u30a2\u30cb\u30b8\u30f3\u3068\u3057\u3066110 mg\/\u65e5\uff09\u306e\u5b89\u5168\u6027\u304c\u98df\u54c1\u5b89\u5168\u59d4\u54e1\u4f1a\u306b\u3088\u308a\u8a55\u4fa1\u3055\u308c\u3066\u3044\u308b\u3002\u305d\u306e\u7d50\u679c\u3001\u98df\u7d4c\u9a13\u3001in vitro\u3001in vivo\u8a66\u9a13\u3001\u30d2\u30c8\u8a66\u9a13\u306e\u5b89\u5168\u6027\u306b\u4fc2\u308b\u90e8\u5206\u306e\u5185\u5bb9\u3092\u5be9\u67fb\u3057\u3001\u3044\u305a\u308c\u3082\u300c\u9069\u5207\u306b\u6442\u53d6\u3055\u308c\u308b\u5834\u5408\u306b\u306f\u3001\u5b89\u5168\u6027\u306b\u554f\u984c\u306f\u306a\u3044\u300d\u3068\u5224\u65ad\u3055\u308c\u3066\u3044\u308b\u3002\u307e\u305f\u3001in vitro\u8a66\u9a13\u53ca\u3073in vitro\u8a66\u9a13\u306b\u304a\u3051\u308b\u5b89\u5168\u6027\u8a66\u9a13\u306e\u6210\u7e3e\u304b\u3089\u3001\u5909\u7570\u539f\u6027\u3001\u4e00\u822c\u6bd2\u6027\u306f\u8a8d\u3081\u3089\u308c\u306a\u3044\u3068\u63a8\u5b9a\u3055\u308c\u305f\u3002\u52a0\u3048\u3066\u3001\u672c\u5c4a\u51fa\u54c1\u306e\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u306e\u4e00\u65e5\u5f53\u305f\u308a\u306e\u6442\u53d6\u76ee\u5b89\u91cf\u306e2\u500d\u91cf\uff08\u30ea\u30f3\u30b4\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb600mg\/\u65e5\u3001\u308a\u3093\u3054\u7531\u6765\u30d7\u30ed\u30b7\u30a2\u30cb\u30b8\u30f3\u3068\u3057\u3066110mg\/\u65e5\uff09\u3092\u542b\u3080\u98f2\u6599\u3092\u7528\u3044\u305f\u81e8\u5e8a\u8a66\u9a13\u306b\u304a\u3044\u3066\u3001\u8a66\u9a13\u98f2\u6599\u306e\u6442\u53d6\u306b\u8d77\u56e0\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u6709\u5bb3\u4e8b\u8c61\u306f\u8a8d\u3081\u3089\u308c\u306a\u304b\u3063\u305f\u3002
\n\u30d1\u30a4\u30ca\u30c3\u30d7\u30eb\u7531\u6765\u30b0\u30eb\u30b3\u30b7\u30eb\u30bb\u30e9\u30df\u30c9\u306b\u304a\u3044\u3066\u672c\u5c4a\u51fa\u98df\u54c1\u306e1\u65e5\u6442\u53d6\u76ee\u5b89\u91cf\u3068\u540c\u3058\u91cf\u3067\u3042\u308b\u3001\u30d1\u30a4\u30ca\u30c3\u30d7\u30eb\u7531\u6765\u30b0\u30eb\u30b3\u30b7\u30eb\u30bb\u30e9\u30df\u30c91.2mg\u3092\u542b\u3080\u98df\u54c1\u306e12\u9031\u9593\u6442\u53d6\u8a66\u9a13\u306b\u3064\u3044\u3066\u3001\u30d1\u30a4\u30ca\u30c3\u30d7\u30eb\u7531\u6765\u30b0\u30eb\u30b3\u30b7\u30eb\u30bb\u30e9\u30df\u30c9\u6442\u53d6\u306b\u3088\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u6709\u5bb3\u4e8b\u8c61\u306e\u5831\u544a\u306f\u7121\u304b\u3063\u305f\u3002\u307e\u305f\u30011\u65e5\u6442\u53d6\u76ee\u5b89\u91cf\u306e5\u500d\u91cf\u3068\u306a\u308b\u30d1\u30a4\u30ca\u30c3\u30d7\u30eb\u7531\u6765\u30b0\u30eb\u30b3\u30b7\u30eb\u30bb\u30e9\u30df\u30c9\u3092\u542b\u3080\u98df\u54c1\uff08\u30d1\u30a4\u30ca\u30c3\u30d7\u30eb\u7531\u6765\u30b0\u30eb\u30b3\u30b7\u30eb\u30bb\u30e9\u30df\u30c91.2mg\u00d75=6.0mg\uff09\u306e4\u9031\u9593\u6442\u53d6\u8a66\u9a13\u306b\u304a\u3044\u3066\u3082\u30d1\u30a4\u30ca\u30c3\u30d7\u30eb\u7531\u6765\u30b0\u30eb\u30b3\u30b7\u30eb\u30bb\u30e9\u30df\u30c9\u6442\u53d6\u306b\u3088\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u6709\u5bb3\u4e8b\u8c61\u306e\u5831\u544a\u306f\u7121\u304b\u3063\u305f\u3002\u307e\u305f\u3001\u5404\u6210\u5206\u306e\u533b\u85ac\u54c1\u3068\u306e\u76f8\u4e92\u4f5c\u7528\u3084\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u540c\u58eb\u306e\u76f8\u4e92\u4f5c\u7528\u306b\u95a2\u3059\u308b\u60c5\u5831\u306f\u7121\u304b\u3063\u305f\u305f\u3081\u3001\u672c\u5c4a\u51fa\u98df\u54c1\u3092\u9069\u5207\u306b\u6442\u53d6\u3059\u308b\u5834\u5408\u3001\u5b89\u5168\u6027\u306b\u554f\u984c\u306a\u3044\u3068\u8a55\u4fa1\u3057\u305f\u3002<\/p>\n

\u6a5f\u80fd\u6027\u306b\u95a2\u3059\u308b\u57fa\u672c\u60c5\u5831<\/h2>\n

\u6a5f\u80fd\u6027\u306e\u8a55\u4fa1\u65b9\u6cd5<\/h3>\n

\u25a0\u6700\u7d42\u88fd\u54c1\u3067\u306f\u306a\u304f\u3001\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u306b\u95a2\u3059\u308b\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\u3067\u3001\u6a5f\u80fd\u6027\u3092\u8a55\u4fa1\u3057\u3066\u3044\u308b\u3002<\/p>\n

\u5f53\u8a72\u88fd\u54c1\u306e\u6a5f\u80fd\u6027\u306b\u95a2\u3059\u308b\u5c4a\u51fa\u8005\u306e\u8a55\u4fa1<\/h3>\n

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\n\u80cc\u666f\uff1a\u4f53\u5185\u3067\u306f\u7cd6\u3068\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u975e\u9175\u7d20\u7684\u306b\u53cd\u5fdc\u3059\u308b\u7cd6\u5316\u53cd\u5fdc\u304c\u304a\u3053\u308a\u3001\u305d\u306e\u7d50\u679cAGEs\uff08\u6700\u7d42\u7cd6\u5316\u7523\u7269:Advanced Glycation Endproducts\uff09\u304c\u751f\u6210\u3059\u308b\u3002\u3053\u306e\u3088\u3046\u306a\u7cd6\u5316\u30b9\u30c8\u30ec\u30b9\u306b\u3088\u3063\u3066\u751f\u6210\u3059\u308bAGEs\u306e\u4e00\u7a2e\u30da\u30f3\u30c8\u30b7\u30b8\u30f3\u306f\u3001\u30b3\u30e9\u30fc\u30b2\u30f3\u5206\u5b50\u9593\u3092\u975e\u7279\u7570\u7684\u306b\u67b6\u6a4b\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u30b3\u30e9\u30fc\u30b2\u30f3\u306e\u7acb\u4f53\u69cb\u9020\u306b\u5f71\u97ff\u3057\u3001\u76ae\u819a\u306b\u304a\u3044\u3066\u6c34\u5206\u5024\u306b\u5f71\u97ff\u3059\u308b\u3002\u30ed\u30c0\u30f3\u30c6\u30ce\u30f3\uff22\u306f\u7cd6\u5316\u53cd\u5fdc\u3092\u963b\u5bb3\u3059\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u308b\u3002\u305d\u3053\u3067\u3001\u30ed\u30c0\u30f3\u30c6\u30ce\u30f3\uff22\u304c\u808c\u306e\u6c34\u5206\u91cf\u3092\u7dad\u6301\u3059\u308b\u52b9\u679c\u304c\u3042\u308b\u304b\u3001\u691c\u8a3c\u3057\u305f\u4ee5\u524d\u306e\u30ec\u30d3\u30e5\u30fc\u3092PRISMA2020\u306b\u6e96\u62e0\u3055\u305b\u308b\u305f\u3081\u3001\u66f4\u65b0\u3092\u884c\u3063\u305f\u3002
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\n\u4e3b\u306a\u7d50\u679c\uff1a\u63a1\u7528\u8ad6\u6587\u306f\u3001\u76ae\u819a\u306e\u305f\u308b\u307f\u3084\u304f\u3059\u307f\u306a\u3069\u306e\u72b6\u614b\u306b\u81ea\u899a\u75c7\u72b6\u306e\u3042\u308b20\u6b73\u4ee3\u304b\u308950\u6b73\u4ee3\u306e\u5065\u5e38\u306a\u65e5\u672c\u4eba\u5973\u6027\u3092\u5bfe\u8c61\u306b\u3001\u30ed\u30c0\u30f3\u30c6\u30ce\u30f3\uff22\uff080.16 mg\/\u65e5\uff09\u309212\u9031\u9593\u6442\u53d6\u3057\u305fRCT\u3067\u3042\u3063\u305f\u3002\u30d7\u30e9\u30bb\u30dc\u6442\u53d6\u306b\u6bd4\u8f03\u3057\u3066\u3001\u808c\u306e\u6c34\u5206\u91cf\uff08\u76ae\u819a\u89d2\u5c64\u6c34\u5206\u91cf\uff09\u304c\u7d71\u8a08\u5b66\u7684\u306b\u6709\u610f\u306b\u9ad8\u304b\u3063\u305f\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u3066\u304a\u308a\u3001\u305d\u306e\u808c\u306e\u6c34\u5206\u91cf\u3092\u4fdd\u6301\u3059\u308b\u6a5f\u80fd\u306f\u7cd6\u5316\u30b9\u30c8\u30ec\u30b9\u3092\u8efd\u6e1b\u3059\u308b\u3053\u3068\u306b\u3088\u308b\u3082\u306e\u3068\u8ad6\u6587\u3067\u8003\u5bdf\u3055\u308c\u3066\u3044\u305f\u3002
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