{"id":39871,"date":"2025-12-26T07:50:51","date_gmt":"2025-12-25T22:50:51","guid":{"rendered":"https:\/\/yakujihou-marketing.net\/database\/?p=39871"},"modified":"2026-04-13T02:31:09","modified_gmt":"2026-04-12T17:31:09","slug":"k819","status":"publish","type":"post","link":"https:\/\/yakujihou-marketing.net\/database\/k819\/","title":{"rendered":"\u30cd\u30eb\u30a8\u30a4\u30c9(K819)"},"content":{"rendered":"\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\u5c4a\u51fa\u756a\u53f7<\/td>\nK819<\/td>\n<\/tr>\n
\u5546\u54c1\u540d<\/td>\n\u30cd\u30eb\u30a8\u30a4\u30c9<\/td>\n<\/tr>\n
\u5c4a\u51fa\u8005\u540d<\/td>\nDIC\u682a\u5f0f\u4f1a\u793e<\/td>\n<\/tr>\n
\u5c4a\u51fa\u65e5<\/td>\n2025\/12\/26<\/td>\n<\/tr>\n
\u5909\u66f4\u65e5<\/td>\n–<\/td>\n<\/tr>\n
\u64a4\u56de\u65e5<\/td>\n–<\/td>\n<\/tr>\n
\u8ca9\u58f2\u4e2d<\/td>\n\u8ca9\u58f2\u4f11\u6b62\u4e2d<\/td>\n<\/tr>\n
\u98df\u54c1\u306e\u533a\u5206<\/td>\n\u52a0\u5de5\u98df\u54c1(\u9320\u5264\u3001\u30ab\u30d7\u30bb\u30eb\u5264\u7b49)<\/td>\n<\/tr>\n
\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u540d<\/td>\nGABA\u3001 \u690d\u7269\u6027\u4e73\u9178\u83ccK-1 (L. casei 327)<\/td>\n<\/tr>\n
\u8868\u793a\u3057\u3088\u3046\u3068\u3059\u308b\u6a5f\u80fd\u6027<\/td>\n\u672c\u54c1\u306b\u306fGABA\u3001\u690d\u7269\u6027\u4e73\u9178\u83ccK-1\uff08L. casei 327\uff09\u304c\u542b\u307e\u308c\u307e\u3059\u3002GABA\u306b\u306f\u3001\u4e00\u6642\u7684\u306a\u75b2\u52b4\u611f\u3084\u30b9\u30c8\u30ec\u30b9\u3092\u611f\u3058\u3066\u3044\u308b\u65b9\u306e\u7761\u7720\u306e\u8cea\uff08\u7720\u308a\u306e\u6df1\u3055\uff09\u306e\u5411\u4e0a\u306b\u5f79\u7acb\u3061\u3001\u3059\u3063\u304d\u308a\u3068\u3057\u305f\u76ee\u899a\u3081\u3092\u30b5\u30dd\u30fc\u30c8\u3059\u308b\u6a5f\u80fd\u304c\u3042\u308b\u3053\u3068\u3001\u65e5\u5e38\u751f\u6d3b\u3067\u751f\u3058\u308b\u4e00\u6642\u7684\u306a\u6d3b\u6c17\u30fb\u6d3b\u529b\u611f\uff08\u7a4d\u6975\u7684\u306a\u6c17\u5206\u3001\u3044\u304d\u3044\u304d\u3068\u3057\u305f\u6c17\u5206\u3001\u3084\u308b\u6c17\u306a\u3069\uff09\u306e\u4f4e\u4e0b\u3092\u8efd\u6e1b\u3057\u3001\u4ed5\u4e8b\u3084\u5bb6\u4e8b\u306a\u3069\u306b\u3088\u308b\u4e00\u6642\u7684\u306a\u75b2\u52b4\u611f\u3084\u30b9\u30c8\u30ec\u30b9\u3092\u548c\u3089\u3052\u308b\u6a5f\u80fd\u304c\u3042\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u690d\u7269\u6027\u4e73\u9178\u83ccK-1\uff08L. casei 327\uff09\u306b\u306f\u3001\u304a\u306a\u304b\u306e\u8abf\u5b50\u3092\u6574\u3048\u3066\u304a\u901a\u3058\u3092\u6539\u5584\u3059\u308b\u6a5f\u80fd\u304c\u3042\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/td>\n<\/tr>\n
\u5f53\u8a72\u88fd\u54c1\u304c\u60f3\u5b9a\u3059\u308b\u4e3b\u306a\u5bfe\u8c61\u8005<\/td>\n\u5065\u5eb7\u306a\u6210\u4eba\u7537\u5973\u3001\u4fbf\u79d8\u6c17\u5473\u306e\u5065\u5e38\u6210\u4eba<\/td>\n<\/tr>\n
\u4e00\u65e5\u5f53\u305f\u308a\u306e\u6442\u53d6\u76ee\u5b89\u91cf<\/td>\n8\u7c92<\/td>\n<\/tr>\n
\u4e00\u65e5\u3042\u305f\u308a\u306e\u6442\u53d6\u76ee\u5b89\u91cf\u5f53\u305f\u308a\u306e\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u306e\u542b\u6709\u91cf<\/td>\n\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u540d\uff1aGABA\u3001\u690d\u7269\u6027\u4e73\u9178\u83ccK-1\uff08L. casei 327\uff09
\n\u542b\u6709\u91cf\uff1aGABA\uff1a100mg\u3001\u690d\u7269\u6027\u4e73\u9178\u83ccK-1\uff08L. casei 327\uff09\uff1a500\u5104\u500b<\/td>\n<\/tr>\n
\u4fdd\u5b58\u306e\u65b9\u6cd5<\/td>\n\u76f4\u5c04\u65e5\u5149\u3001\u9ad8\u6e29\u30fb\u591a\u6e7f\u306e\u5834\u6240\u3092\u907f\u3051\u3066\u4fdd\u5b58\u3057\u3066\u4e0b\u3055\u3044\u3002<\/td>\n<\/tr>\n
\u6442\u53d6\u306e\u65b9\u6cd5<\/td>\n1\u65e5\u5f53\u305f\u308a8\u7c92\u3092\u76ee\u5b89\u306b\u3001\u6c34\u306a\u3069\u3068\u4e00\u7dd2\u306b\u304a\u53ec\u3057\u4e0a\u304c\u308a\u304f\u3060\u3055\u3044\u3002<\/td>\n<\/tr>\n
\u6442\u53d6\u3092\u3059\u308b\u4e0a\u3067\u306e\u6ce8\u610f\u4e8b\u9805<\/td>\n\u25cf\u30b9\u30d4\u30eb\u30ea\u30ca\u306f\u7d0d\u8c46\u306a\u3069\u3068\u540c\u69d8\u306b\u30d3\u30bf\u30df\u30f3K\u3092\u591a\u304f\u542b\u3093\u3067\u3044\u307e\u3059\u3002\u30ef\u30eb\u30d5\u30a1\u30ea\u30f3\u3092\u670d\u7528\u3055\u308c\u3066\u3044\u308b\u65b9\u306f\u6442\u53d6\u3092\u304a\u63a7\u3048\u304f\u3060\u3055\u3044\u3002
\n\u25cf\u964d\u5727\u85ac\u3092\u670d\u7528\u3057\u3066\u3044\u308b\u65b9\u306f\u533b\u5e2b\u3001\u85ac\u5264\u5e2b\u306b\u76f8\u8ac7\u3057\u3066\u304f\u3060\u3055\u3044\u3002
\n\u25cf\u5e38\u306b\u6d3b\u6c17\u30fb\u6d3b\u529b\u611f\u304c\u51fa\u306a\u3044\u3001\u4f11\u6687\u30fb\u7761\u7720\u3092\u3068\u3063\u3066\u3082\u75b2\u52b4\u611f\u304c\u629c\u3051\u306a\u3044\u65b9\u306f\u3001\u3046\u3064\u75c5\u3084\u6162\u6027\u75b2\u52b4\u75c7\u5019\u7fa4\u7b49\u306e\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u306e\u3067\u3001\u533b\u5e2b\u306e\u8a3a\u5bdf\u3092\u304a\u52e7\u3081\u3057\u307e\u3059\u3002
\n\u25cf\u690d\u7269\u7531\u6765\u306e\u539f\u6599\u3092\u4f7f\u7528\u3057\u3066\u3044\u308b\u305f\u3081\u3001\u8272\u306e\u3070\u3089\u3064\u304d\u3084\u8272\u3080\u3089\u304c\u3042\u308b\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002\u307e\u305f\u3001\u6e7f\u6c17\u3067\u7c92\u306e\u5909\u8272\u3084\u5272\u308c\u304c\u304a\u3053\u308b\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u54c1\u8cea\u306b\u306f\u554f\u984c\u3042\u308a\u307e\u305b\u3093\u3002
\n\u25cf\u8131\u9178\u7d20\u5264\u304c\u5165\u3063\u3066\u3044\u307e\u3059\u3002\u8aa4\u3063\u3066\u53ec\u3057\u4e0a\u304c\u3089\u306a\u3044\u3067\u304f\u3060\u3055\u3044\u3002<\/td>\n<\/tr>\n
\u8abf\u7406\u53c8\u306f\u4fdd\u5b58\u306e\u65b9\u6cd5\u306b\u95a2\u3057\u7279\u306b\u6ce8\u610f\u3092\u5fc5\u8981\u3068\u3059\u308b\u3082\u306e\u306b\u3042\u3063\u3066\u306f\u5f53\u8a72\u6ce8\u610f\u4e8b\u9805<\/td>\n\u25cf\u7c92\u306f\u306c\u308c\u305f\u624b\u3067\u89e6\u3089\u305a\u3001\u885b\u751f\u7684\u306b\u304a\u53d6\u6271\u3044\u304f\u3060\u3055\u3044\u3002
\n\u25cf\u5f37\u3044\u885d\u6483\u306b\u3088\u308a\u7c92\u304c\u5272\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/td>\n<\/tr>\n
\u6d88\u8cbb\u8005\u5e81URL<\/td>\nhttps:\/\/www.fld.caa.go.jp\/caaks\/s\/cssc01\/fwccd01?c__id=a09RA00000Lw6p1YAB<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u5b89\u5168\u6027\u306b\u95a2\u3059\u308b\u57fa\u672c\u60c5\u5831<\/h2>\n

\u5b89\u5168\u6027\u306e\u8a55\u4fa1\u65b9\u6cd5<\/h3>\n

\u25a0\u65e2\u5b58\u60c5\u5831\u306b\u3088\u308b\u5b89\u5168\u6027\u8a66\u9a13\u7d50\u679c\u306e\u8a55\u4fa1\u306b\u3088\u308a\u3001\u5341\u5206\u306a\u5b89\u5168\u6027\u3092\u78ba\u8a8d\u3057\u3066\u3044\u308b\u3002<\/p>\n

\u5f53\u8a72\u88fd\u54c1\u306e\u5b89\u5168\u6027\u306b\u95a2\u3059\u308b\u5c4a\u51fa\u8005\u306e\u8a55\u4fa1<\/h3>\n

\u3010GABA\u3011
\n\u65e2\u5b58\u60c5\u5831\u306b\u3088\u308b\u98df\u7d4c\u9a13\u306e\u8a55\u4fa1\u3067\u306f\u4e0d\u5341\u5206\u3067\u3042\u3063\u305f\u305f\u3081\u3001\u5b89\u5168\u6027\u8a66\u9a13\u306b\u3088\u308b\u8a55\u4fa1\u3092\u884c\u3063\u305f\u3002
\n\u3007\u5b89\u5168\u6027\u8a66\u9a13\u306b\u3088\u308b\u8a55\u4fa1\uff1a10\uff5e1,000 mg\u306eGABA\u3092\u5358\u56de\uff5e12\u9031\u9593\u6442\u53d6\u3057\u305f\u5834\u5408\u306b\u3001\u8efd\u5ea6\u306e\u81ea\u899a\u75c7\u72b6\u5909\u5316\u3092\u8a34\u3048\u308b\u4e8b\u4f8b\uff08\u4e0b\u75e2\u306a\u3069\uff09\u306f\u3042\u308b\u3082\u306e\u306e\u3001\u5b89\u5168\u6027\u306b\u554f\u984c\u306f\u306a\u304b\u3063\u305f\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3002\u66f4\u306b\u672c\u5c4a\u51fa\u54c1\u306b\u542b\u307e\u308c\u308bGABA\u3092\u7528\u3044\u305f\u5b89\u5168\u6027\u8a66\u9a13\uff08\u2460GABA 241.5\u338e\u309213\u9031\u9593\u7d99\u7d9a\u6442\u53d6\u2461GABA 1207.7mg\u30924\u9031\u9593\u7d99\u7d9a\u6442\u53d6\uff09\u3092\u5b9f\u65bd\u3057\u3001\u3044\u305a\u308c\u3082\u5b89\u5168\u6027\u306b\u554f\u984c\u306a\u3044\u3053\u3068\u3092\u78ba\u8a8d\u3057\u3066\u3044\u308b\u3002\u3053\u3053\u304b\u3089\u3001\u672c\u5c4a\u51fa\u54c1\u306b\u542b\u307e\u308c\u308bGABA\u306b\u306f\u5341\u5206\u306a\u5b89\u5168\u6027\u304c\u3042\u308b\u3068\u5224\u65ad\u3067\u304d\u308b\u3002
\nGABA\u306f\u5358\u7d14\u306a\u69cb\u9020\u306e\u30a2\u30df\u30ce\u9178\u3067\u3042\u308a\u3001\u57fa\u539f\u306b\u3088\u308b\u6027\u8cea\u306e\u9055\u3044\u306f\u751f\u3058\u306a\u3044\u305f\u3081\u3001\u5404\u5b89\u5168\u6027\u8a66\u9a13\u3067\u7528\u3044\u3089\u308c\u305fGABA\u3068\u672c\u5c4a\u51fa\u54c1\u306b\u542b\u307e\u308c\u308bGABA\u306f\u540c\u7b49\u306e\u3082\u306e\u3067\u3042\u308b\u3068\u8a00\u3048\u308b\u3002
\n\u4ee5\u4e0a\u306e\u3053\u3068\u304b\u3089\u3001GABA\u3092\u914d\u5408\u3057\u305f\u672c\u5c4a\u51fa\u54c1\u306e\u5b89\u5168\u6027\u306b\u554f\u984c\u306f\u306a\u3044\u3068\u8003\u3048\u3089\u308c\u308b\u3002\u307e\u305f\u3001GABA\u306e\u533b\u85ac\u54c1\u3068\u306e\u76f8\u4e92\u4f5c\u7528\u306b\u3064\u3044\u3066\u554f\u984c\u306a\u3044\u3068\u5224\u65ad\u3057\u305f\u304c\u3001\u5ff5\u306e\u305f\u3081\u3001\u6442\u53d6\u4e0a\u306e\u6ce8\u610f\u306b\u3001\u964d\u5727\u5264\u7b49\u306e\u533b\u85ac\u54c1\u670d\u7528\u8005\u306f\u672c\u5c4a\u51fa\u54c1\u306e\u5229\u7528\u306b\u3064\u3044\u3066\u533b\u5e2b\u3001\u85ac\u5264\u5e2b\u306b\u76f8\u8ac7\u3059\u3079\u304d\u3067\u3042\u308b\u65e8\u3092\u8868\u793a\u3057\u3066\u3044\u308b\u3002<\/p>\n

\u3010\u690d\u7269\u6027\u4e73\u9178\u83ccK-1\uff08L. casei 327\uff09\u3011
\n\u690d\u7269\u6027\u4e73\u9178\u83ccK-1\uff08L. casei 327\uff09\u304c\u5c5e\u3059\u308b\u83cc\u7a2e L. casei\u306f\u3001\u98df\u7d4c\u9a13\u306e\u3042\u308b\u83cc\u7a2e\u3068\u3057\u3066EFSA\uff08\u6b27\u5dde\u98df\u54c1\u5b89\u5168\u6a5f\u95a2\uff09\u306e Qualified Presumption of Safety (QPS)\u306b\u63b2\u8f09\u3055\u308c\u3066\u3044\u308b\u3002
\n\u6587\u732e\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u3092\u7528\u3044\u3066\u65e2\u5b58\u60c5\u5831\u691c\u7d22\u3092\u884c\u3063\u305f\u3068\u3053\u308d\u3001\u690d\u7269\u6027\u4e73\u9178\u83ccK-1\uff08L. casei 327\uff09\u3092500\u5104\u500b\uff5e5000\u5104\u500b\u306e\u83cc\u6570\u3067\u7d99\u7d9a\u7684\u306b\u6442\u53d6\u3055\u305b\u305f\u8a66\u9a13\u304c\u30012\u4ef6\u306e\u6587\u732e\u30673\u4f8b\u5831\u544a\u3055\u308c\u3066\u3044\u305f\u3002\u3044\u305a\u308c\u306e\u8a66\u9a13\u306b\u304a\u3044\u3066\u3082\u3001\u8a66\u9a13\u98df\u306b\u8d77\u56e0\u3059\u308b\u6709\u5bb3\u4e8b\u8c61\u306f\u8a8d\u3081\u3089\u308c\u3066\u3044\u306a\u3044\u3002
\n\u307e\u305f\u3001\u533b\u85ac\u54c1\u3068\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u3068\u306e\u76f8\u4e92\u4f5c\u7528\u306e\u6709\u7121\u306b\u3064\u3044\u3066\u6587\u732e\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u3092\u7528\u3044\u3066\u8abf\u67fb\u3057\u305f\u7d50\u679c\u3001\u533b\u85ac\u54c1\u3068\u306e\u76f8\u4e92\u4f5c\u7528\u306b\u95a2\u3059\u308b\u6709\u5bb3\u4e8b\u8c61\u3082\u8a8d\u3081\u3089\u308c\u3066\u3044\u306a\u3044\u3002
\n\u4e0a\u8a18\u3067\u4f7f\u7528\u3055\u308c\u3066\u3044\u308b\u690d\u7269\u6027\u4e73\u9178\u83ccK-1\uff08L. casei 327\uff09\u306f\u672c\u54c1\u306b\u4f7f\u7528\u3055\u308c\u3066\u3044\u308b\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u3068\u540c\u4e00\u306e\u539f\u6599\u3067\u3042\u308a\u3001\u540c\u7b49\u6027\u306f\u5341\u5206\u306b\u62c5\u4fdd\u3055\u308c\u3066\u3044\u308b\u3068\u5224\u65ad\u3057\u305f\u3002\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u540c\u58eb\u306e\u76f8\u4e92\u4f5c\u7528\u306b\u3064\u3044\u3066\u3082\u61f8\u5ff5\u3055\u308c\u308b\u60c5\u5831\u306f\u78ba\u8a8d\u3067\u304d\u306a\u304b\u3063\u305f\u3002\u305d\u306e\u305f\u3081\u3001\u7dcf\u5408\u7684\u306a\u5224\u65ad\u3068\u3057\u3066\u3001\u672c\u54c1\u306e\u4e00\u65e5\u6442\u53d6\u76ee\u5b89\u91cf\u3092\u5b88\u308a\u9069\u5207\u306b\u6442\u53d6\u3059\u308b\u5834\u5408\u3001\u5b89\u5168\u6027\u306b\u554f\u984c\u306f\u306a\u3044\u3068\u5224\u65ad\u3057\u305f\u3002<\/p>\n

\u6a5f\u80fd\u6027\u306b\u95a2\u3059\u308b\u57fa\u672c\u60c5\u5831<\/h2>\n

\u6a5f\u80fd\u6027\u306e\u8a55\u4fa1\u65b9\u6cd5<\/h3>\n

\u25a0\u6700\u7d42\u88fd\u54c1\u3067\u306f\u306a\u304f\u3001\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u306b\u95a2\u3059\u308b\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\u3067\u3001\u6a5f\u80fd\u6027\u3092\u8a55\u4fa1\u3057\u3066\u3044\u308b\u3002<\/p>\n

\u5f53\u8a72\u88fd\u54c1\u306e\u6a5f\u80fd\u6027\u306b\u95a2\u3059\u308b\u5c4a\u51fa\u8005\u306e\u8a55\u4fa1<\/h3>\n

\u3010\u6a19\u984c\u3011\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206GABA\u306b\u3088\u308b\u7761\u7720\u306e\u8cea\u306e\u6a5f\u80fd\u6027\u306b\u95a2\u3059\u308b\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\u66f4\u65b0\u7248
\n\u3010\u76ee\u7684\u3011GABA\u6442\u53d6\u306b\u3088\u308b\u7761\u7720\u306e\u8cea\uff08\u7720\u308a\u306e\u6df1\u3055\uff09\u306e\u6539\u5584\u52b9\u679c\u3092\u691c\u8a0e\u3057\u305f\u3002
\n\u3010\u80cc\u666f\u3011GABA\u306f\u7cbe\u795e\u7684\u30b9\u30c8\u30ec\u30b9\u304c\u304b\u304b\u308b\u4f5c\u696d\u306b\u304a\u3051\u308b\u4e00\u6642\u7684\u306a\u75b2\u52b4\u611f\u306e\u8efd\u6e1b\u3084\u3001\u7761\u7720\u306e\u8cea\u306e\u6539\u5584\u304c\u65e2\u306b\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3002
\n\u3010\u30ec\u30d3\u30e5\u30fc\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u306e\u7279\u6027\u3011\u56fd\u5185\u5916\u306e\u6587\u732e\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u3092\u691c\u7d22\u3057\u3001\u5065\u5eb7\u6210\u4eba\u5bfe\u8c61\u3067GABA\u30fb\u30d7\u30e9\u30bb\u30dc\u6442\u53d6\u6642\u3092\u6bd4\u8f03\u3057\u305f\u8a66\u9a13\u3067\u8133\u6ce2\u3092\u8a55\u4fa1\u3057\u3066\u3044\u308b\u6587\u732e2\u5831\u3092\u8a55\u4fa1\u3057\u305f\u3002
\n\u3010\u4e3b\u306a\u7d50\u679c\u3011GABA\u6442\u53d6(100 mg\/\u65e5)\u306e\u7d50\u679c\u3001\u63a1\u7528\u6587\u732e2\u5831\u3067\u6df1\u3044\u7761\u7720\u6642\u9593\u304c\u6709\u610f\u306b\u5897\u52a0\u3057\u305f\u3002\u307e\u305f1\u5831\u3067\u306f\u3001\u30b9\u30c8\u30ec\u30b9\u72b6\u6cc1\u3084\u75b2\u52b4\u611f\u306e\u9055\u3044\u306b\u3088\u308b\u5c64\u5225\u89e3\u6790\u3092\u5b9f\u65bd\u3057\u305f\u5834\u5408\u3001\u4e00\u6642\u7684\u306a\u75b2\u52b4\u611f\u3084\u30b9\u30c8\u30ec\u30b9\u3092\u3088\u308a\u611f\u3058\u3066\u3044\u308b\u4eba\u306e\u30ce\u30f3\u30ec\u30e0\u7761\u7720\u30b9\u30c6\u30fc\u30b83\u306e\u6642\u9593\u304c\u6709\u610f\u306b\u5897\u52a0\u3057\u305f\u3002
\n\u3010\u79d1\u5b66\u7684\u6839\u62e0\u306e\u8cea\u3011\u30a8\u30d3\u30c7\u30f3\u30b9\u7dcf\u4f53\u306f\u3001\u30d0\u30a4\u30a2\u30b9\u30ea\u30b9\u30af\u3068\u975e\u76f4\u63a5\u6027\u306f\u4f4e(0)\u3001\u4e0d\u7cbe\u78ba\u306f\u88ab\u9a13\u8005\u6570\u306e\u5c11\u306a\u3044\u7814\u7a76\u304c\u542b\u307e\u308c\u308b\u306e\u307f\u3067\u3042\u3063\u305f\u305f\u3081\u9ad8(-2)\u3001\u975e\u4e00\u8cab\u6027\u306f2\u5831\u3067\u8a55\u4fa1\u7d50\u679c\u306b\u9055\u3044\u304c\u3042\u308b\u304c\u88ab\u9a13\u8005\u7279\u6027\u306b\u3088\u308b\u5f71\u97ff\u3068\u601d\u308f\u308c\u4e2d\/\u7591\u3044(-1)\u3001\u305d\u306e\u4ed6(\u51fa\u7248\u30d0\u30a4\u30a2\u30b9\u306a\u3069)\u306f\u672a\u5831\u544a\u7814\u7a76\u3067\u51fa\u7248\u30d0\u30a4\u30a2\u30b9\u306e\u6050\u308c\u306e\u3042\u308b\u7814\u7a76\u304c2\u5831\u78ba\u8a8d\u3055\u308c\u305f\u305f\u3081\u4e2d\/\u7591\u3044(-1)\u3068\u8a55\u4fa1\u3057\u305f\u3002\u5408\u8a08-4\u3068\u306a\u308a\u30a8\u30d3\u30c7\u30f3\u30b9\u78ba\u5b9f\u6027\u306f\u4e2d(B)\u3068\u5224\u65ad\u3057\u305f\u3002\u9650\u754c\u3068\u3057\u3066\u3001\u63a1\u7528\u6587\u732e\u304c2\u5831\u3068\u5c11\u306a\u304f\u4e0d\u7cbe\u78ba\u304c\u5426\u5b9a\u3067\u304d\u306a\u3044\u3053\u3068\u3001\u8a00\u8a9e\u30d0\u30a4\u30a2\u30b9\u3001\u51fa\u7248\u30d0\u30a4\u30a2\u30b9\u304c\u5b8c\u5168\u306b\u5426\u5b9a\u3067\u304d\u306a\u3044\u3053\u3068\u304c\u6319\u3052\u3089\u308c\u3001\u4eca\u5f8c\u306e\u66f4\u306a\u308b\u7814\u7a76\u304c\u5fc5\u8981\u3067\u3042\u308b\u3002
\n\u3010\u6a19\u984c\u3011\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206GABA\u306b\u3088\u308b\u7761\u7720\u306e\u8cea(\u76ee\u899a\u3081)\u306e\u6a5f\u80fd\u6027\u306b\u95a2\u3059\u308b\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\u66f4\u65b0\u7248
\n\u3010\u76ee\u7684\u3011GABA\u6442\u53d6\u306b\u3088\u308b\u7761\u7720\u306e\u8cea(\u76ee\u899a\u3081)\u306e\u6539\u5584\u6a5f\u80fd\u3092\u691c\u8a0e\u3057\u305f\u3002
\n\u3010\u80cc\u666f\u3011GABA\u306f\u7cbe\u795e\u7684\u30b9\u30c8\u30ec\u30b9\u304c\u304b\u304b\u308b\u4f5c\u696d\u306b\u304a\u3051\u308b\u4e00\u6642\u7684\u306a\u75b2\u52b4\u611f\u306e\u8efd\u6e1b\u3084\u3001\u7761\u7720\u306e\u8cea\u306e\u6539\u5584\u304c\u65e2\u306b\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3002
\n\u3010\u30ec\u30d3\u30e5\u30fc\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u306e\u7279\u6027\u3011\u56fd\u5185\u5916\u306e\u6587\u732e\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u3092\u691c\u7d22\u3057\u3001\u5065\u5eb7\u6210\u4eba\u5bfe\u8c61\u3067GABA\u30fb\u30d7\u30e9\u30bb\u30dc\u6442\u53d6\u6642\u3092\u6bd4\u8f03\u3057\u305f\u8a66\u9a13\u3067\u3001\u4e3b\u89b3\u7684\u6307\u6a19\u3067\u3042\u308bVAS\u306e\u3046\u3061\u7761\u7720\u306e\u8cea(\u76ee\u899a\u3081)\u3092\u8a55\u4fa1\u3057\u3066\u3044\u308b\u6587\u732e1\u5831\u3092\u8a55\u4fa1\u3057\u305f\u3002
\n\u3010\u4e3b\u306a\u7d50\u679c\u3011GABA\u6442\u53d6(100 mg\/\u65e5)\u306e\u7d50\u679c\u3001\u63a1\u7528\u6587\u732e1\u5831\u3067\u3001VAS\u3010feelings upon awakening\u3011\u306e\u6e2c\u5b9a\u5024\u304c\u6709\u610f\u306b\u5897\u52a0\u3057\u305f\u3002
\n\u3010\u79d1\u5b66\u7684\u6839\u62e0\u306e\u8cea\u3011\u30a8\u30d3\u30c7\u30f3\u30b9\u7dcf\u4f53\u306f\u3001\u30d0\u30a4\u30a2\u30b9\u30ea\u30b9\u30af\u306f\u4e2d\/\u7591\u3044(-1)\u3001\u975e\u76f4\u63a5\u6027\u306f\u4f4e(0)\u3068\u8a55\u4fa1\u3057\u305f\u3002\u4e0d\u7cbe\u78ba\u6027\u306b\u3064\u3044\u3066\u306f\u88ab\u9a13\u8005\u6570\u306e\u5c11\u306a\u3044\u7814\u7a76\u306e\u307f\u3067\u3042\u3063\u305f\u305f\u3081\u9ad8(-2)\u3001\u975e\u4e00\u8cab\u6027\u306f\u63a1\u7528\u6587\u732e\u304c1\u5831\u3067\u3042\u308b\u305f\u3081\u9ad8(-2)\u3068\u8a55\u4fa1\u3057\u305f\u3002\u305d\u306e\u4ed6(\u51fa\u7248\u30d0\u30a4\u30a2\u30b9\u306a\u3069)\u306e\u8a55\u4fa1\u306f\u63a1\u7528\u6587\u732e1\u5831\u306e\u305d\u306e\u4ed6\u306e\u30d0\u30a4\u30a2\u30b9\u30ea\u30b9\u30af\u304c-1\u3067\u3042\u308a\u3001\u672a\u5831\u544a\u7814\u7a76\u3067\u51fa\u7248\u30d0\u30a4\u30a2\u30b9\u306e\u6050\u308c\u306e\u3042\u308b\u7814\u7a76\u304c2\u5831\u78ba\u8a8d\u3055\u308c\u305f\u305f\u3081\u9ad8(-2)\u3068\u8a55\u4fa1\u3057\u305f\u3002\u5408\u8a08-7\u3068\u306a\u308a\u3001\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u78ba\u5b9f\u6027\u306f\u4f4e(C)\u3068\u5224\u65ad\u3057\u305f\u3002\u9650\u754c\u3068\u3057\u3066\u3001\u63a1\u7528\u6587\u732e\u304c1\u5831\u306e\u307f\u3067\u51fa\u7248\u30d0\u30a4\u30a2\u30b9\u53ca\u3073\u975e\u4e00\u8cab\u6027\u304c\u3042\u308b\u53ef\u80fd\u6027\u3092\u5426\u5b9a\u3067\u304d\u306a\u3044\u3053\u3068\u3001\u63a1\u7528\u6587\u732e\u306e\u88ab\u9a13\u8005\u6570\u304c\u5c11\u306a\u304f\u4e0d\u7cbe\u78ba\u304c\u5426\u5b9a\u3067\u304d\u306a\u3044\u3053\u3068\u3001\u8a00\u8a9e\u30d0\u30a4\u30a2\u30b9\u304c\u5426\u5b9a\u3067\u304d\u306a\u3044\u3053\u3068\u304c\u6319\u3052\u3089\u308c\u3001\u4eca\u5f8c\u306e\u66f4\u306a\u308b\u7814\u7a76\u304c\u5fc5\u8981\u3067\u3042\u308b\u3002
\n\u3010\u6a19\u984c\u3011\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206GABA\u306b\u3088\u308b\u6d3b\u6c17\u30fb\u6d3b\u529b\u611f\u306e\u4f4e\u4e0b\u306b\u4e0e\u3048\u308b\u6a5f\u80fd\u6027\u306b\u95a2\u3059\u308b\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\u66f4\u65b0\u7248
\n\u3010\u76ee\u7684\u3011\u4e00\u6642\u7684\u306b\u6d3b\u6c17\u30fb\u6d3b\u529b\u611f\u304c\u4f4e\u4e0b\u3057\u3066\u3044\u308b\u5065\u5eb7\u306a\u6210\u4eba\u7537\u5973\u3067\u3001GABA\u6442\u53d6\u306b\u3088\u308b\u4e00\u6642\u7684\u306a\u6d3b\u6c17\u30fb\u6d3b\u529b\u611f\u306e\u4f4e\u4e0b\u3092\u8efd\u6e1b\u3059\u308b\u6a5f\u80fd\u306b\u3064\u3044\u3066\u691c\u8a3c\u3057\u305f\u3002
\n\u3010\u80cc\u666f\u3011\u7cbe\u795e\u7684\u4f5c\u696d\u3084\u8eab\u4f53\u7684\u4f5c\u696d\u306e\u5897\u52a0\u306f\u3001\u4e00\u6642\u7684\u306b\u6d3b\u6c17\u3084\u6d3b\u529b(\u751f\u304d\u751f\u304d\u3068\u3057\u305f\u72b6\u614b\u306a\u3069)\u304c\u4f4e\u4e0b\u3057\u3001\u4f5c\u696d\u52b9\u7387\u3084\u793e\u4f1a\u5168\u4f53\u306e\u6d3b\u52d5\u306b\u5927\u304d\u304f\u5f71\u97ff\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u3002
\n\u3010\u30ec\u30d3\u30e5\u30fc\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u306e\u7279\u6027\u3011\u56fd\u5185\u5916\u306e\u6587\u732e\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u3092\u691c\u7d22\u3057\u3001\u4e00\u6642\u7684\u306b\u6d3b\u6c17\u30fb\u6d3b\u529b\u611f\u304c\u4f4e\u4e0b\u3057\u3066\u3044\u308b\u5065\u5eb7\u306a\u6210\u4eba\u7537\u5973\u3092\u5bfe\u8c61\u306bGABA\u3092\u6442\u53d6\u3057\u3001\u4e00\u6642\u7684\u306a\u6d3b\u6c17\u30fb\u6d3b\u529b\u611f\u306b\u4e0e\u3048\u308b\u5f71\u97ff\u3092\u8a55\u4fa1\u3057\u305f\u6587\u732e4\u5831\u3092\u8a55\u4fa1\u3057\u305f\u3002
\n\u3010\u4e3b\u306a\u7d50\u679c\u3011\u6d3b\u6c17\u30fb\u6d3b\u529b\u611f\u306e\u8a55\u4fa1\u306e\u7d50\u679c\u3001\u4e00\u6642\u7684\u306b\u6d3b\u529b\u304c\u4f4e\u4e0b\u3057\u3066\u3044\u308b\u4eba\u3067\u306f\u3001100 mg\u306eGABA\u3092\u7d99\u7d9a\u6442\u53d6\u3001\u3042\u308b\u3044\u306f\u30b9\u30c8\u30ec\u30b9\u8ca0\u8377\u5f8c\u306e\u5358\u56de\u6442\u53d6\u3067\u300c\u6d3b\u6c17\u30fb\u6d3b\u529b\u300d\u306e\u4f4e\u4e0b\u3092\u8efd\u6e1b\u3059\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u305f\u3002
\n\u3010\u79d1\u5b66\u7684\u6839\u62e0\u306e\u8cea\u3011\u30a8\u30d3\u30c7\u30f3\u30b9\u7dcf\u4f53\u306b\u304a\u3044\u3066\u3001\u30d0\u30a4\u30a2\u30b9\u30ea\u30b9\u30af\u3001\u975e\u76f4\u63a5\u6027\u3001\u4e0d\u7cbe\u78ba\u3001\u975e\u4e00\u8cab\u6027\u3001\u305d\u306e\u4ed6\uff08\u51fa\u7248\u30d0\u30a4\u30a2\u30b9\u306a\u3069\uff09\u306f\u4f4e(0)\u3068\u5224\u65ad\u3057\u3001\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u78ba\u5b9f\u6027\u306f\u9ad8(A)\u3068\u5224\u65ad\u3057\u305f\u3002\u9650\u754c\u3068\u3057\u3066\u3001\u63a1\u7528\u6587\u732e4\u5831\u4e2d1\u5831\u3067\u80af\u5b9a\u7684\u306a\u7d50\u679c\u304c\u5f97\u3089\u308c\u3066\u3044\u306a\u3044\u70ba\u3001\u975e\u4e00\u8cab\u6027\u3092\u5b8c\u5168\u306b\u5426\u5b9a\u3067\u304d\u306a\u3044\u3053\u3068\u3001\u8a00\u8a9e\u30d0\u30a4\u30a2\u30b9\u3092\u5b8c\u5168\u306b\u5426\u5b9a\u3067\u304d\u306a\u3044\u3053\u3068\u304c\u6319\u3052\u3089\u308c\u3001\u4eca\u5f8c\u306e\u66f4\u306a\u308b\u7814\u7a76\u304c\u5fc5\u8981\u3067\u3042\u308b\u3002
\n\u3010\u6a19\u984c\u3011\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206GABA\u306b\u3088\u308b\u4e00\u6642\u7684\u306a\u7cbe\u795e\u7684\u30b9\u30c8\u30ec\u30b9\u3084\u75b2\u52b4\u611f\u306e\u7de9\u548c\u306b\u95a2\u3059\u308b\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\u66f4\u65b0\u7248
\n\u3010\u76ee\u7684\u3011\u65e5\u5e38\u751f\u6d3b\u306b\u304a\u3051\u308b\u4e00\u6642\u7684\u306a\u7cbe\u795e\u7684\u30b9\u30c8\u30ec\u30b9\u3084\u75b2\u52b4\u611f\u306b\u5bfe\u3059\u308bGABA\u6442\u53d6\u306e\u6a5f\u80fd\u6027\u3092\u691c\u8a3c\u3057\u305f\u3002
\n\u3010\u80cc\u666f\u3011\u52b4\u50cd\u8005\u306b\u53d7\u3051\u308b\u30b9\u30c8\u30ec\u30b9\u3084\u75b2\u52b4\u611f\u306f\u62e1\u5927\u50be\u5411\u306b\u3042\u308a\u3001\u69d8\u3005\u306a\u98df\u54c1\u7d20\u6750\u306b\u3088\u308b\u75b2\u52b4\u611f\u3084\u30b9\u30c8\u30ec\u30b9\u7de9\u548c\u3092\u76ee\u7684\u3068\u3057\u305f\u7814\u7a76\u304c\u76db\u3093\u306b\u884c\u308f\u308c\u3066\u3044\u308b\u3002
\n\u3010\u30ec\u30d3\u30e5\u30fc\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u306e\u7279\u6027\u3011\u56fd\u5185\u5916\u306e\u6587\u732e\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u3092\u691c\u7d22\u3057\u3001\u5065\u5eb7\u6210\u4eba\u5bfe\u8c61\u306bGABA\u30fb\u30d7\u30e9\u30bb\u30dc\u6442\u53d6\u6642\u3092\u6bd4\u8f03\u3057\u305f\u8a66\u9a13\u3067\u3042\u308a\u3001\u30b9\u30c8\u30ec\u30b9\u3084\u75b2\u52b4\u611f\u306b\u95a2\u9023\u3059\u308b\u6307\u6a19\u3092\u5831\u544a\u3057\u3066\u3044\u308b\u6587\u732e7\u5831\u3092\u8a55\u4fa1\u3057\u305f\u3002
\n\u3010\u4e3b\u306a\u7d50\u679c\u3011\u4e00\u6642\u7684\u306a\u30b9\u30c8\u30ec\u30b9\u3084\u75b2\u52b4\u611f\u3092\u8a55\u4fa1\u3059\u308b\u6307\u6a19\u300c\u4e3b\u89b3\u7684\u6307\u6a19(VAS\u3001POMS)\u3001\u5ba2\u89b3\u7684\u6307\u6a19(\u553e\u6db2\u4e2d\u306e\u30b3\u30eb\u30c1\u30be\u30fc\u30eb\u30fb\u30af\u30ed\u30e2\u30b0\u30e9\u30cb\u30f3A\u3001\u8133\u6ce2\u306e\u5909\u52d5\u3001\u81ea\u5f8b\u795e\u7d4c\u6d3b\u52d5\u306e\u5404\u6307\u6a19)\u300d\u3092\u8a55\u4fa1\u3057\u305f\u7d50\u679c\u300128mg\u4ee5\u4e0a\u6442\u53d6\u3067\u7cbe\u795e\u7684\u30b9\u30c8\u30ec\u30b9\u304c\u304b\u304b\u308b\u4f5c\u696d\u8ca0\u8377\u5f8c\u306e\u4e00\u6642\u7684\u306a\u7cbe\u795e\u7684\u30b9\u30c8\u30ec\u30b9\u3084\u75b2\u52b4\u611f\u3092\u7de9\u548c\u3059\u308b\u50cd\u304d\u304c\u3042\u308b\u3068\u5224\u65ad\u3057\u305f\u3002
\n\u3010\u79d1\u5b66\u7684\u6839\u62e0\u306e\u8cea\u3011\u30a8\u30d3\u30c7\u30f3\u30b9\u7dcf\u4f53\u306f\u3001\u75b2\u52b4\u611fVAS\u306f-2\u3001\u75b2\u52b4\u611fPOMS\u3001\u30af\u30ed\u30e2\u30b0\u30e9\u30cb\u30f3A\u306f-4\u3001\u30b3\u30eb\u30c1\u30be\u30fc\u30eb\u306f-6\u3001\u8133\u6ce2\u306e\u5909\u52d5\u306f-2\u3001\u81ea\u5f8b\u795e\u7d4c\u6d3b\u52d5\u306f-4\u3067\u3042\u308a\u3001\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u78ba\u5b9f\u6027\u306f\u9806\u306b\u9ad8(A)\u3001\u4e2d(B)\u3001\u4e2d(B)\u3001\u4f4e(C)\u3001\u9ad8(A)\u3001\u4e2d(B)\u3068\u8a55\u4fa1\u3057\u305f\u3002\u9650\u754c\u3068\u3057\u3066\u3001\u553e\u6db2\u4e2d\u30b9\u30c8\u30ec\u30b9\u30de\u30fc\u30ab\u30fc(\u30af\u30ed\u30e2\u30b0\u30e9\u30cb\u30f3A\u3001\u30b3\u30eb\u30c1\u30be\u30fc\u30eb)\u3001\u81ea\u5f8b\u795e\u7d4c\u6d3b\u52d5\u306b\u304a\u3044\u3066\u306f\u88ab\u9a13\u8005\u6570\u304c\u5c11\u306a\u304f\u7cbe\u78ba\u6027\u304c\u5426\u5b9a\u3067\u304d\u305a\u3001\u553e\u6db2\u4e2d\u30b9\u30c8\u30ec\u30b9\u30de\u30fc\u30ab\u30fc(\u30af\u30ed\u30e2\u30b0\u30e9\u30cb\u30f3A\u3001\u30b3\u30eb\u30c1\u30be\u30fc\u30eb)\u3067\u306f\u975e\u4e00\u8cab\u6027\u304c\u5426\u5b9a\u3067\u304d\u306a\u3044\u3002\u8a00\u8a9e\u30d0\u30a4\u30a2\u30b9\u304a\u3088\u3073\u51fa\u7248\u30d0\u30a4\u30a2\u30b9\u306b\u3064\u3044\u3066\u306f\u5426\u5b9a\u3067\u304d\u306a\u3044\u3053\u3068\u304c\u6319\u3052\u3089\u308c\u308b\u3002
\n\u3010\u6a19\u984c\u3011\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\u300c\u690d\u7269\u6027\u4e73\u9178\u83cc K-1\uff08L. casei 327\uff09\u300d\u306e\u4fbf\u901a\u6539\u5584\u4f5c\u7528\u306b\u95a2\u3059\u308b\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc \u66f4\u65b0\u7248
\n\u3010\u80cc\u666f\u30fb\u76ee\u7684\u3011\u4fbf\u79d8\u306f\u5065\u5eb7\u72b6\u614b\u3084\u751f\u6d3b\u306e\u8cea\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u8981\u56e0\u3067\u3042\u308a\u3001\u6539\u5584\u304c\u671b\u307e\u308c\u3066\u3044\u308b\u3002\u690d\u7269\u6027\u4e73\u9178\u83cc K-1\uff08L. casei 327\uff09\u306f\u4fbf\u901a\u6539\u5584\u304c\u671f\u5f85\u3055\u308c\u3001\u6700\u8fd1\u3067\u306f\u81e8\u5e8a\u8a66\u9a13\u306e\u5b9f\u65bd\u306b\u3088\u308a\u6709\u52b9\u6027\u304c\u78ba\u8a8d\u3055\u308c\u308b\u7b49\u305d\u306e\u6709\u7528\u6027\u304c\u898b\u51fa\u3055\u308c\u3066\u3044\u308b\u3002\u305d\u3053\u3067\u3001\u300c\u5065\u5eb7\u306a\u6210\u4eba\u304c\u690d\u7269\u6027\u4e73\u9178\u83cc K-1\uff08L. casei 327\uff09\u3092\u542b\u3080\u98df\u54c1\u3092\u6442\u53d6\u3059\u308b\u3068\u4fbf\u901a\u306f\u6539\u5584\u3059\u308b\u306e\u304b\u300d\u3092\u691c\u8a3c\u3059\u308b\u305f\u3081\u3001\u4ee4\u548c7\u5e743\u670825\u65e5\u306b\u4ea4\u4ed8\u3055\u308c\u305f\u6a5f\u80fd\u6027\u8868\u793a\u98df\u54c1\u306e\u5c4a\u51fa\u7b49\u544a\u793a(\u5185\u95a3\u5e9c\u544a\u793a\u7b2c35\u53f7)\u7b49\u306b\u9069\u7528\u3055\u305b\u305f\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\u3092\u5b9f\u65bd\u3057\u305f\u3002
\n\u3010\u30ec\u30d3\u30e5\u30fc\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u306e\u7279\u6027\u3011\u30ea\u30b5\u30fc\u30c1\u30af\u30a8\u30b9\u30c1\u30e7\u30f3(RQ)\u53ca\u3073PICOS\u3092\u4ee5\u4e0b\u306e\u3088\u3046\u306b\u8a2d\u5b9a\u3057\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\u3092\u5b9f\u65bd\u3057\u305f\u3002
\nRQ\uff1a\u5065\u5eb7\u306a\u6210\u4eba\u304c\u690d\u7269\u6027\u4e73\u9178\u83cc K-1\uff08L. casei 327\uff09\u3092\u542b\u3080\u98df\u54c1\u3092\u6442\u53d6\u3059\u308b\u3068\u4fbf\u901a\u306f\u6539\u5584\u3059\u308b\u306e\u304b\u3001P\uff1a\u5065\u5eb7\u306a\u6210\u4eba(\u4fbf\u79d8\u50be\u5411\u8005\u3092\u542b\u3080)\u3001I\uff1a\u690d\u7269\u6027\u4e73\u9178\u83ccK-1\uff08L. casei 327\uff09\u3092\u542b\u3080\u98df\u54c1\u306e\u7d4c\u53e3\u6442\u53d6(\u98df\u54c1\u5f62\u614b\u306f\u554f\u308f\u306a\u3044)\u3001C\uff1a\u30d7\u30e9\u30bb\u30dc\u98df\u54c1\u306e\u7d4c\u53e3\u6442\u53d6(\u30d7\u30e9\u30bb\u30dc\u306e\u914d\u5408\u5185\u5bb9\u306f\u554f\u308f\u306a\u3044)\u3001O\uff1a\u4fbf\u901a\u3001S\uff1a\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13
\n\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u691c\u7d22\u306b\u3088\u308a\u7279\u5b9a\u3055\u308c\u305f\u6587\u732e\u306f\u3001\u9069\u683c\u57fa\u6e96\u306b\u3088\u308a\u6587\u732e\u3092\u9078\u5225\u3057\u3001\u63a1\u7528\u6587\u732e\u304b\u3089PICOS\u306b\u5bfe\u5fdc\u3057\u305f\u9805\u76ee\u306e\u60c5\u5831\u3092\u62bd\u51fa\u3057\u305f\u3002\u307e\u305f\u3001\u539f\u8457\u8ad6\u6587\u3067\u3042\u308b\u304b\u3001\u67fb\u8aad\u8a8c\u3067\u3042\u308b\u304b\u78ba\u8a8d\u3057\u305f\u3002
\n\u3010\u4e3b\u306a\u7d50\u679c\u3011\u6700\u7d42\u7684\u306b2\u5831\u3092\u63a1\u7528\u3057\u3001\u690d\u7269\u6027\u4e73\u9178\u83cc K-1\uff08L. casei 327\uff09500\u5104\u500b\u30012\u9031\u9593\u306e\u6442\u53d6\u3067\u4fbf\u901a\u304c\u6539\u5584\u3059\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u3001\u8868\u793a\u3057\u3088\u3046\u3068\u3059\u308b\u6a5f\u80fd\u6027\u306f\u59a5\u5f53\u3068\u5224\u65ad\u3057\u305f\u3002\u63a1\u7528\u8ad6\u6587\u306f\u81e8\u5e8a\u8a66\u9a13\u304c\u65e5\u672c\u3067\u5b9f\u65bd\u3055\u308c\u3066\u3044\u308b\u3053\u3068\u3088\u308a\u3001\u65e5\u672c\u4eba\u306e\u5916\u633f\u6027\u306e\u554f\u984c\u306f\u306a\u3044\u3068\u5224\u65ad\u3057\u305f\u3002
\n\u3010\u79d1\u5b66\u7684\u6839\u62e0\u306e\u8cea\u3011\u5168\u7814\u7a76\u306e\u30d0\u30a4\u30a2\u30b9\u30ea\u30b9\u30af\u3001\u975e\u76f4\u63a5\u6027\u3001\u4e0d\u7cbe\u78ba\u3001\u975e\u4e00\u8cab\u6027\u306f\u4f4e\u3001\u305d\u306e\u4ed6(\u51fa\u7248\u30d0\u30a4\u30a2\u30b9\u306a\u3069)\u306f\u63a1\u7528\u6587\u732e2\u5831\u3068\u3082\u540c\u4e00\u306e\u7814\u7a76\u6a5f\u95a2\u306b\u3088\u308b\u5831\u544a\u304c\u3042\u308b\u306e\u307f\u3067\u3042\u308b\u305f\u3081\u9ad8\u3068\u5224\u65ad\u3057\u305f\u3002\u6700\u7d42\u7684\u306a\u5168\u4f53\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u5f37\u3055\u306f\u4e2d(B)\u3068\u5224\u65ad\u3057\u305f\u3002\u9650\u754c\u3068\u3057\u3066\u3001\u63a1\u7528\u6587\u732e\u304c2\u5831\u3068\u5c11\u306a\u304f\u3001\u6f5c\u5728\u7684\u306b\u51fa\u7248\u30d0\u30a4\u30a2\u30b9\u304c\u5b58\u5728\u3059\u308b\u53ef\u80fd\u6027\u306f\u5426\u5b9a\u3067\u304d\u306a\u3044\u305f\u3081\u3001\u5f15\u304d\u7d9a\u304d\u691c\u8a0e\u304c\u5fc5\u8981\u3060\u3068\u8003\u3048\u3089\u308c\u308b\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

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