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\n\u5065\u5e38\u6210\u4eba\u304a\u3088\u3073\u8840\u4e2d\u4e2d\u6027\u8102\u80aa\u304c\u3084\u3084\u9ad8\u3081\u306e\u6210\u4eba\u3092\u5bfe\u8c61\u3068\u3057\u3066\u3001\u96e3\u6d88\u5316\u6027\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\u306e\u5358\u56de\u6442\u53d6\u304c\u30d7\u30e9\u30bb\u30dc\u306e\u5358\u56de\u6442\u53d6\u3068\u6bd4\u8f03\u3057\u3001\u8102\u80aa\u5438\u53ce\u6291\u5236\u4f5c\u7528\u3092\u793a\u3059\u304b\u3092\u691c\u8a3c\u3059\u308b\u305f\u3081\u306b\u3001\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u3092\u7db2\u7f85\u7684\u306b\u691c\u7d22\u3057\u305f\u3002\u56fd\u5185\u5916\u306e\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u30672019\u5e741\u670822\u65e5\u30682\u67085\u65e5\u306b\u691c\u7d22\u3092\u884c\u3044\u3001\u691c\u7d22\u65e5\u4ee5\u524d\u306b\u767a\u8868\u3055\u308c\u305f\u6587\u732e\u3092\u96c6\u3081\u305f\u3068\u3053\u308d\u3001\u6761\u4ef6\u3092\u6e80\u305f\u3057\u305f\u6587\u732e\u306f9\u5831\u3067\u3042\u3063\u305f\u3002<\/p>\n

\u30aa\uff0e\u4e3b\u306a\u7d50\u679c
\n\u8a55\u4fa1\u5bfe\u8c619\u7814\u7a76\u306b\u304a\u3044\u3066\u3001\u96e3\u6d88\u5316\u6027\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\u306e\u5358\u56de\u6442\u53d6\u306f\u3001\u30d7\u30e9\u30bb\u30dc\u306e\u5358\u56de\u6442\u53d6\u3068\u6bd4\u8f03\u3057\u3066\u3001\u300c\u98df\u5f8c\u8840\u4e2d\u4e2d\u6027\u8102\u80aa\u5024\u66f2\u7dda\u4e0b\u9762\u7a4d\uff08AUC0-6h\uff09\u300d\u306e\u6709\u610f\u306a\u4f4e\u4e0b\u304c\u8a8d\u3081\u3089\u308c\u305f\u3002\u307e\u305f\u3001\u4e00\u822c\u306bAUC\u306f\u5438\u53ce\u91cf\u3092\u6e2c\u5b9a\u3059\u308b\u6307\u6a19\u3068\u3057\u3066\u7528\u3044\u3089\u308c\u308b\u3053\u3068\u304b\u3089\u3001\u96e3\u6d88\u5316\u6027\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\u306e\u5358\u56de\u6442\u53d6\u306f\u3001\u8102\u80aa\u306e\u5438\u53ce\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u304c\u671f\u5f85\u3067\u304d\u308b\u3068\u8003\u3048\u3089\u308c\u305f\u3002\u8102\u80aa\u306e\u5438\u53ce\u6291\u5236\u4f5c\u7528\u304c\u8a8d\u3081\u3089\u308c\u305f6\u7814\u7a76\u306e\u96e3\u6d88\u5316\u6027\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\u3068\u3057\u3066\uff091\u56de\u6442\u53d6\u91cf\u306f5\uff5e5.2 g\u3067\u3001\u3046\u30615\u7814\u7a76\u304c5 g\u3067\u3042\u3063\u305f\u3053\u3068\u304b\u3089\u3001\u96e3\u6d88\u5316\u6027\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\u3068\u3057\u3066\uff095 g\u3092\u98df\u4e8b\u3068\u3068\u3082\u306b\u6442\u53d6\u3059\u308b\u3068\u3001\u8102\u80aa\u306e\u5438\u53ce\u3092\u6291\u5236\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u305f\u3002\u306a\u304a\u3001\u5065\u5e38\u6210\u4eba\u306e\u307f\u306b\u304a\u3044\u3066\u3082\u540c\u69d8\u306e\u52b9\u679c\u304c\u78ba\u8a8d\u3055\u308c\u305f\u3002<\/p>\n

\u30ab\uff0e\u79d1\u5b66\u7684\u6839\u62e0\u306e\u8cea
\n\u8a55\u4fa1\u5bfe\u8c61\u7814\u7a76\u306b\u304a\u3044\u3066\u3001\u8a66\u9a13\u30c7\u30b6\u30a4\u30f3\u306b\u304a\u3051\u308b\u30d0\u30a4\u30a2\u30b9\u304c\u8a8d\u3081\u3089\u308c\u305f\u3002\u307e\u305f\u3001\u80af\u5b9a\u7684\u306a\u7d50\u679c\u3088\u308a\u3082\u5426\u5b9a\u7684\u306a\u7d50\u679c\u304c\u516c\u8868\u3055\u308c\u306b\u304f\u3044\u3068\u3044\u3046\u51fa\u7248\u30d0\u30a4\u30a2\u30b9\u306e\u5b58\u5728\u3082\u5426\u5b9a\u3055\u308c\u306a\u304b\u3063\u305f\u304c\u3001\u3044\u305a\u308c\u3082\u7d50\u679c\u3078\u306e\u5f71\u97ff\u306f\u4f4e\u3044\u3068\u8003\u3048\u3089\u308c\u3001\u30a8\u30d3\u30c7\u30f3\u30b9\u7dcf\u4f53\u306f\u5f37\uff08\uff21\uff09\u3068\u5224\u65ad\u3055\u308c\u305f\u3002\u305f\u3060\u3057\u3001\u4ea4\u7d61\u56e0\u5b50\u306e\u5f71\u97ff\u7b49\u306b\u3064\u3044\u3066\u3001\u3055\u3089\u306a\u308b\u7814\u7a76\u304c\u5fc5\u8981\u3068\u8003\u3048\u3089\u308c\u305f\u3002<\/p>\n

\uff12\uff0e\u98df\u4e8b\u304b\u3089\u6442\u53d6\u3057\u305f\u7cd6\u8cea\u306e\u5438\u53ce\u3092\u6291\u3048\u308b\u6a5f\u80fd
\n\u30a2\uff0e\u6a19\u984c
\n\u300c\u96e3\u6d88\u5316\u6027\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\uff09\u300d\u306e\u7cd6\u8cea\u306e\u5438\u53ce\u6291\u5236\u4f5c\u7528\u306b\u95a2\u3059\u308b\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u3092\u542b\u3080\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc<\/p>\n

\u30a4\uff0e\u76ee\u7684
\n\u5065\u5e38\u6210\u4eba\uff08\u8840\u7cd6\u5024\u304c\u5883\u754c\u578b\u306e\u8005\u3092\u542b\u3080\uff09\u3092\u5bfe\u8c61\u3068\u3057\u3066\u3001\u96e3\u6d88\u5316\u6027\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\u306e\u5358\u56de\u6442\u53d6\u304c\u30d7\u30e9\u30bb\u30dc\u306e\u5358\u56de\u6442\u53d6\u3068\u6bd4\u8f03\u3057\u3001\u7cd6\u8cea\u306e\u5438\u53ce\u6291\u5236\u4f5c\u7528\u3092\u793a\u3059\u304b\u3092\u3001\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u3092\u542b\u3080\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\u3067\u691c\u8a3c\u3059\u308b\u3002<\/p>\n

\u30a6\uff0e\u80cc\u666f
\n\u73fe\u5728\u3001\u7cd6\u5c3f\u75c5\u60a3\u8005\u6570\u306e\u5897\u52a0\u306f\u3001\u8d85\u9ad8\u9f62\u793e\u4f1a\u3092\u8fce\u3048\u305f\u65e5\u672c\u306b\u304a\u3044\u3066\u6975\u3081\u3066\u6df1\u523b\u306a\u554f\u984c\u306e\u3072\u3068\u3064\u3068\u306a\u3063\u3066\u3044\u308b\u3002\u7cd6\u5c3f\u75c5\u306b\u7f79\u60a3\u3057\u306a\u3044\u305f\u3081\u306b\u306f\u3001\u98df\u4e8b\u7642\u6cd5\u306a\u3069\u306b\u3088\u308a\u98df\u5f8c\u8840\u7cd6\u5024\u3092\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3059\u308b\u3053\u3068\u304c\u975e\u5e38\u306b\u91cd\u8981\u3067\u3042\u308b\u3053\u3068\u304b\u3089\u3001\u98df\u4e8b\u304b\u3089\u6442\u53d6\u3057\u305f\u7cd6\u8cea\u306e\u5438\u53ce\u3092\u6291\u5236\u3057\u98df\u5f8c\u8840\u7cd6\u5024\u306e\u4e0a\u6607\u3092\u6291\u5236\u3059\u308b\u98df\u54c1\u7d20\u6750\u304c\u6ce8\u76ee\u3055\u308c\u3066\u3044\u308b\u3002
\n\u96e3\u6d88\u5316\u6027\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\u306f\u69d8\u3005\u306a\u98df\u54c1\u306b\u5229\u7528\u3055\u308c\u3066\u304a\u308a\u3001\u30d2\u30c8\u3067\u98df\u4e8b\u304b\u3089\u6442\u53d6\u3057\u305f\u7cd6\u8cea\u306e\u5438\u53ce\u3092\u6291\u5236\u3057\u3066\u98df\u5f8c\u8840\u7cd6\u4e0a\u6607\u6291\u5236\u4f5c\u7528\u3092\u6709\u3059\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u304c\u3001\u3053\u308c\u307e\u3067\u306b\u96e3\u6d88\u5316\u6027\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\u306e\u7cd6\u8cea\u306e\u5438\u53ce\u6291\u5236\u4f5c\u7528\u306b\u3064\u3044\u3066\u3001\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u3067\u691c\u8a3c\u3057\u305f\u5831\u544a\u306f\u306a\u304b\u3063\u305f\u3002<\/p>\n

\u30a8\uff0e\u30ec\u30d3\u30e5\u30fc\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u306e\u7279\u6027
\n\u5065\u5e38\u6210\u4eba\uff08\u8840\u7cd6\u5024\u304c\u5883\u754c\u578b\u306e\u8005\u3092\u542b\u3080\uff09\u3092\u5bfe\u8c61\u3068\u3057\u3001\u96e3\u6d88\u5316\u6027\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\u306e\u5358\u56de\u6442\u53d6\u304c\u30d7\u30e9\u30bb\u30dc\u306e\u5358\u56de\u6442\u53d6\u3068\u6bd4\u8f03\u3057\u3066\u3001\u7cd6\u8cea\u306e\u5438\u53ce\u6291\u5236\u4f5c\u7528\u3092\u793a\u3059\u304b\u3092\u691c\u8a3c\u3059\u308b\u305f\u3081\u3001\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u3092\u7db2\u7f85\u7684\u306b\u691c\u7d22\u3057\u305f\u3002\u56fd\u5185\u5916\u306e\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u3092\u4f7f\u7528\u3057\u30662019\u5e742\u67085\u65e5\u30682\u67088\u65e5\u306b\u691c\u7d22\u3092\u884c\u3044\u3001\u691c\u7d22\u65e5\u4ee5\u524d\u306b\u767a\u8868\u3055\u308c\u305f\u6587\u732e\u3092\u96c6\u3081\u305f\u3068\u3053\u308d\u3001\u6761\u4ef6\u3092\u6e80\u305f\u3057\u305f\u6587\u732e\u306f24\u5831\u3067\u3042\u3063\u305f\u3002<\/p>\n

\u30aa\uff0e\u4e3b\u306a\u7d50\u679c
\n\u8a55\u4fa1\u5bfe\u8c6124\u7814\u7a76\u306b\u304a\u3044\u3066\u3001\u96e3\u6d88\u5316\u6027\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\u306e\u5358\u56de\u6442\u53d6\u306f\u3001\u30d7\u30e9\u30bb\u30dc\u306e\u5358\u56de\u6442\u53d6\u3068\u6bd4\u8f03\u3057\u3066\u3001\u300c\u98df\u5f8c\u8840\u7cd6\u5024\u66f2\u7dda\u4e0b\u9762\u7a4d\uff08AUC0-2h\uff09\u300d\u306e\u6709\u610f\u306a\u4f4e\u4e0b\u304c\u8a8d\u3081\u3089\u308c\u305f\u3002\u307e\u305f\u3001\u4e00\u822c\u306bAUC\u306f\u5438\u53ce\u91cf\u3092\u6e2c\u5b9a\u3059\u308b\u6307\u6a19\u3068\u3057\u3066\u7528\u3044\u3089\u308c\u308b\u3053\u3068\u304b\u3089\u3001\u96e3\u6d88\u5316\u6027\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\u306e\u5358\u56de\u6442\u53d6\u306f\u3001\u7cd6\u8cea\u306e\u5438\u53ce\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u304c\u671f\u5f85\u3067\u304d\u308b\u3068\u8003\u3048\u3089\u308c\u305f\u3002\u7cd6\u8cea\u306e\u5438\u53ce\u6291\u5236\u4f5c\u7528\u304c\u8a8d\u3081\u3089\u308c\u305f20\u7814\u7a76\u306e\u96e3\u6d88\u5316\u6027\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\u3068\u3057\u3066\uff091\u56de\u6442\u53d6\u91cf\u306f4.4\uff5e9.8 g\u3067\u3001\u3046\u30619\u7814\u7a76\u304c5 g\u3067\u3042\u3063\u305f\u3053\u3068\u304b\u3089\u3001\u96e3\u6d88\u5316\u6027\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\uff08\u98df\u7269\u7e4a\u7dad\u3068\u3057\u3066\uff095 g\u3092\u98df\u4e8b\u3068\u3068\u3082\u306b\u6442\u53d6\u3059\u308b\u3068\u3001\u7cd6\u8cea\u306e\u5438\u53ce\u3092\u6291\u5236\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u305f\u3002<\/p>\n

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