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\nDHA\u3001EPA \u306e\u6442\u53d6\u304c\u8a8d\u77e5\u6a5f\u80fd\u3001\u8840\u5727\u3001\u4e2d\u6027\u8102\u80aa\u306b\u4e0e\u3048\u308b\u5f71\u97ff\u306b\u3064\u3044\u3066
\n\u3010\u76ee\u7684\u3011
\n\u672c\u7814\u7a76\u306f\u3001\u6210\u4eba\u5065\u5e38\u4eba\u306bDHA\u3001EPA \u542b\u6709\u98df\u54c1\u309212 \u9031\u9593\u7d4c\u53e3\u6442\u53d6\u3055\u305b\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u30d7\u30e9\u30bb\u30dc\u98df\u54c1\u6442\u53d6\u3068\u6bd4\u8f03\u3057\u3066\u3001\u8a8d\u77e5\u6a5f\u80fd\u3084\u5faa\u74b0\u5668\u6a5f\u80fd\u3078\u3069\u306e\u3088\u3046\u306a\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u304b\u691c\u8a3c\u3059\u308b\u3053\u3068\u3092\u76ee\u7684\u3068\u3057\u305f\u3002
\n\u3010\u80cc\u666f\u3011
\n\u865a\u8840\u6027\u5fc3\u75be\u60a3\u3084\u8133\u8840\u7ba1\u969c\u5bb3\u3092\u306f\u3058\u3081\u3068\u3059\u308b\u52d5\u8108\u786c\u5316\u6027\u306e\u5fc3\u5faa\u74b0\u7cfb\u75be\u60a3\uff08CVD\uff09\u306f\u3001\u4eca\u3084\u65e5\u672c\u306e\u6b7b\u56e0\u306e30%\u306b\u3082\u9054\u3057\u3001\u4eca\u5f8c\u3082\u4e0a\u6607\u3059\u308b\u3068\u4e88\u60f3\u3055\u308c\u308b\u3002n-3 \u8102\u80aa\u9178\u306e\u4e00\u7a2e\u3067\u3001\u9b5a\u6cb9\u306a\u3069\u306b\u542b\u307e\u308c\u308b\u4e0d\u98fd\u548c\u8102\u80aa\u9178\u3067\u3042\u308bDHA(\u30c9\u30b3\u30b5\u30d8\u30ad\u30b5\u30a8\u30f3\u9178)\u3068EPA\uff08\u30a8\u30a4\u30b3\u30b5\u30da\u30f3\u30bf\u30a8\u30f3\u9178\uff09\u306fCVD \u767a\u75c7\u30ea\u30b9\u30af\u56e0\u5b50\u3067\u3042\u308b\u8840\u4e2d\u4e2d\u6027\u8102\u80aa\u3001\u8840\u5727\u306a\u3069\u3092\u6709\u610f\u306b\u4f4e\u4e0b\u3055\u305b\u308b\u4f5c\u7528\u3092\u6301\u3064\u3053\u3068\u306f\u69d8\u3005\u306a\u7814\u7a76\u306b\u304a\u3044\u3066\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u304c\u3001\u5065\u5e38\u306a\u88ab\u9a13\u8005\u3092\u5bfe\u8c61\u3068\u3057\u305f\u8a66\u9a13\u306f\u307b\u3068\u3093\u3069\u898b\u5f53\u305f\u3089\u306a\u3044\u3002\u307e\u305f\u3001\u8fd1\u5e74\u3001\u5e7e\u3064\u304bn-3 \u8102\u80aa\u9178\u306e\u6442\u53d6\u306b\u3088\u308b\u8133\u795e\u7d4c\u3078\u4e0e\u3048\u308b\u5f71\u97ff\u306b\u95a2\u3059\u308b\u7814\u7a76\u5831\u544a\u304c\u3055\u308c\u3001DHA \u3068EPA \u306e\u5065\u5eb7\u3078\u4e0e\u3048\u308b\u5f71\u97ff\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u308b\u3002
\n\u3010\u65b9\u6cd5\u3011
\n\u300c\u5bfe\u8c61\u8005\u306e\u7279\u6027\u300d
\nn-3 \u7cfb\u8102\u80aa\u9178\u6442\u53d6\u91cf\u304c\u6bd4\u8f03\u7684\u5c11\u306a\u304450\u6b73\u4ee5\u4e0a70\u6b73\u4ee5\u4e0b\u306e\u5065\u5eb7\u306a\u65e5\u672c\u4eba\u7537\u597366\u540d\u3092\u5bfe\u8c61\u3068\u3057\u305f\u3002
\n\u300c\u7814\u7a76\u30c7\u30b6\u30a4\u30f3\u300d
\n\u8a55\u4fa1\u3092\u3059\u308b\u306b\u3042\u305f\u308a\u5148\u5165\u89b3\u3084\u601d\u3044\u8fbc\u307f\u304c\u751f\u3058\u306a\u3044\u3088\u3046\u306b\u3059\u308b\u305f\u3081\u3001\u7121\u4f5c\u70ba\u5316\u3001\u4e8c\u91cd\u76f2\u691c\u3001\u30d7\u30e9\u30bb\u30dc\u5bfe\u7167\u3001\u4e26\u884c\u7fa4\u9593\u6bd4\u8f03\u8a66\u9a13\u3068\u3057\u305f\u3002
\n\u300c\u6442\u53d6\u6761\u4ef6\u300d
\n\u88ab\u9a13\u98df\uff1a\u7cbe\u88fd\u9b5a\u6cb9\u542b\u6709\u98df\u54c1\u3001\u6a5f\u80fd\u6027\u95a2\u4e0e\u6210\u5206\uff1aDHA\u3001EPA
\n\u6442\u53d6\u91cf\uff1aDHA 544mg\/\u65e5\u3001EPA 59.2 \u338e\/\u65e5\uff081\u65e54\u30ab\u30d7\u30bb\u30eb*1\uff09
\n\u5bfe\u7167\u98df\uff1a\u7cbe\u88fd\u9b5a\u6cb9\u672a\u542b\u6709\u98df\u54c1\uff08\u7cbe\u88fd\u9b5a\u6cb9\u306e\u4ee3\u308f\u308a\u306b\u30aa\u30ea\u30fc\u30d6\u6cb9\u3092\u914d\u5408\u30011\u65e54\u30ab\u30d7\u30bb\u30eb\uff09
\n\u6442\u53d6\u671f\u9593\uff1a12 \u9031\u9593
\n*1 \u81e8\u5e8a\u8a66\u9a13\u3067\u306f\u300c4\u7c92\u300d\u3092\u300c4\u30ab\u30d7\u30bb\u30eb\u300d\u3068\u3044\u3046\u8868\u8a18\u306b\u3057\u3066\u3044\u308b\u3002
\n\u300c\u5229\u76ca\u76f8\u53cd\u300d
\n\u8457\u8005\u306e\u4e00\u90e8\u306f\u5f53\u793e\u5f93\u696d\u54e1\u3067\u3042\u308b\u3002\u307e\u305f\u3001\u8a66\u9a13\u306e\u5b9f\u65bd\u306f\u7b2c\u4e09\u8005\u6a5f\u95a2\u306b\u3088\u3063\u3066\u884c\u308f\u308c\u3001\u5f53\u793e\u306f\u8a66\u9a13\u8cbb\u7528\u3092\u8ca0\u62c5\u3057\u305f\u3002
\n\u3010\u4e3b\u306a\u7d50\u679c\u3011
\n\u5bfe\u8c61\u8005\u306f\u88ab\u9a13\u98df\u7fa4\u3068\u5bfe\u7167\u98df\u7fa4\u3001\u305d\u308c\u305e\u308c33 \u540d\u305a\u3064\u3068\u3057\u305f\u3002\u5185\u3001\u88ab\u9a13\u98df\u7fa45\u540d\u3001\u5bfe\u7167\u98df\u7fa47\u540d\u306f\u89e3\u6790\u5bfe\u8c61\u9664\u5916\u57fa\u6e96\u306b\u8a72\u5f53\u3059\u308b\u7b49\u306e\u7406\u7531\u3067\u3001\u8a66\u9a13\u304b\u3089\u8131\u843d\u3082\u3057\u304f\u306f\u9664\u5916\u3057\u305f\u3002\u5bfe\u8c61\u8005\u306b\u3001\u88ab\u9a13\u98df\u307e\u305f\u306f\u5bfe\u7167\u98df\u309212 \u9031\u9593\u6442\u53d6\u3057\u3066\u3082\u3089\u3044\u3001\u6442\u53d6\u524d\u5f8c\u306b\u304a\u3051\u308b\u8840\u5727\u6e2c\u5b9a\u3001\u8840\u6db2\u691c\u67fb\u3001\u8a8d\u77e5\u6a5f\u80fd\u691c\u67fb\u3092\u5b9f\u65bd\u3057\u305f\u3002\u305d\u306e\u7d50\u679c\u3001\u88ab\u9a13\u98df\u7fa4\u3067\u306f\u3001\u6442\u53d6\u524d\u3068\u6bd4\u8f03\u3057\u3066\u3001\u6442\u53d6\u5f8c\u306f\u8840\u5727\u3001\u4e2d\u6027\u8102\u80aa\u3068\u3082\u306b\u6e1b\u5c11\u3057\u3001\u8a8d\u77e5\u6a5f\u80fd\u691c\u67fb\u306e\u4e00\u90e8\uff08Stroop\u30c6\u30b9\u30c8\u306e\u30b9\u30c6\u30c3\u30d73\uff09\u306b\u304a\u3044\u3066\u4f4e\u4e0b\u3057\u3001\u3053\u306e\u3053\u3068\u306f\u8a8d\u77e5\u6a5f\u80fd\uff08\u5224\u65ad\u80fd\u529b\uff09\u306e\u4e0a\u6607\u3092\u793a\u5506\u3057\u305f\u3002\u307e\u305f\u3001\u300c\u7279\u5b9a\u4fdd\u5065\u7528\u98df\u54c1\u7533\u8acb\u306b\u4fc2\u308b\u7533\u8acb\u66f8\u4f5c\u6210\u4e0a\u306e\u7559\u610f\u4e8b\u9805\u300d\u306b\u8a18\u8f09\u3055\u308c\u308b\u8efd\u75c7\u8005\u304c\u88ab\u9a13\u8005\u306b\u542b\u307e\u308c\u3066\u3044\u305f\u3053\u3068\u304b\u3089\u3001\u8efd\u75c7\u8005\u3092\u9664\u3044\u305f\u75be\u75c5\u306b\u7f79\u60a3\u3057\u3066\u3044\u306a\u3044\u7bc4\u56f2\uff08\u53ce\u7e2e\u671f\u8840\u5727130mmHg \u672a\u6e80\u3001\u62e1\u5f35\u671f\u8840\u572785mmHg \u672a\u6e80\u53ca\u3073\u8840\u4e2d\u4e2d\u6027\u8102\u80aa150mg\/dL \u672a\u6e80\uff09\u306e\u88ab\u9a13\u8005\u306e\u307f\u3092\u5bfe\u8c61\u3068\u3057\u305f\u5c64\u5225\u89e3\u6790\u3092\u884c\u3063\u305f\u3068\u3053\u308d\u3001\u75be\u75c5\u306b\u7f79\u60a3\u3057\u3066\u3044\u306a\u3044\u88ab\u9a13\u8005\u306e\u307f\u306e\u5c64\u306b\u304a\u3044\u3066\u3082\u6a5f\u80fd\u6027\u3092\u652f\u6301\u3059\u308b\u7d50\u679c\u3092\u5f97\u305f\u3002\u306a\u304a\u3001\u3053\u308c\u3089\u306f\u5bfe\u7167\u98df\u7fa4\u3068\u6bd4\u8f03\u3057\u3066\u6709\u610f\u306a\u5909\u5316\u3092\u793a\u3057\u305f\u3002\u307e\u305f\u3001\u75be\u75c5\u306b\u7f79\u60a3\u3057\u3066\u3044\u306a\u3044\u304c\u8840\u5727\u304c\u9ad8\u3081\u306e\u7bc4\u56f2\uff08\u6b63\u5e38\u9ad8\u5024\u4ee5\u4e0b\u3001\u53ce\u7e2e\u671f\u8840\u5727140mmHg \u672a\u6e80\u3001\u62e1\u5f35\u671f\u8840\u572790mmHg \u672a\u6e80\uff09\u306e\u88ab\u9a13\u8005\u306e\u307f\u3092\u5bfe\u8c61\u3068\u3057\u305f\u5c64\u5225\u89e3\u6790\u306b\u304a\u3044\u3066\u3082\u6a5f\u80fd\u6027\u3092\u5426\u5b9a\u3057\u306a\u3044\u7d50\u679c\u3067\u3042\u3063\u305f\u3002\u672c\u8a66\u9a13\u306b\u304a\u3044\u3066\u5065\u5eb7\u3078\u306e\u60aa\u5f71\u97ff\u306f\u8a8d\u3081\u3089\u308c\u306a\u304b\u3063\u305f\u3002
\n\u3010\u79d1\u5b66\u7684\u6839\u62e0\u306e\u8cea\u3011
\n\u672c\u8a66\u9a13\u306f\u3001n-3 \u7cfb\u8102\u80aa\u9178\u6442\u53d6\u91cf\u304c\u6bd4\u8f03\u7684\u5c11\u306a\u3044\u5065\u5e38\u306a\u65e5\u672c\u4eba\u6210\u4eba\u7537\u5973\u3092\u5bfe\u8c61\u306b\u3057\u305f\u70b9\u304c\u7814\u7a76\u306e\u9650\u754c\u3068\u3057\u3066\u6319\u3052\u3089\u308c\u308b\u3002n-3 \u7cfb\u8102\u80aa\u9178\u6442\u53d6\u91cf\u304c\u6bd4\u8f03\u7684\u5c11\u306a\u3044\u5065\u5eb7\u306a\u65e5\u672c\u4eba\u6210\u4eba\u7537\u5973\u306e\u5faa\u74b0\u5668\u6a5f\u80fd\u306e\u6539\u5584\u3001\u4e26\u3073\u306b\u4e2d\u9ad8\u9f62\u8005\u306e\u8a8d\u77e5\u6a5f\u80fd\u6539\u5584\u304c\u671f\u5f85\u3067\u304d\u308b\u3002\uff08\u69cb\u9020\u5316\u6284\u9332\uff09<\/p>\n

\u25a0\u8a72\u5f53\u3059\u308b\u8a55\u4fa1\u3059\u308b\u6a5f\u80fd\u6027\u306e\u9805\u76ee
\n\u300cDHA \u306b\u306f\u3001\u8a8d\u77e5\u6a5f\u80fd\u306e\u4e00\u90e8\u3067\u3042\u308b\u8a18\u61b6\u529b\uff08\u6570\u5b57\u3084\u6587\u5b57\u306a\u3069\u3092\u899a\u3048\u308b\u529b\uff09\u3092\u7dad\u6301\u3059\u308b\u6a5f\u80fd\u304c\u3042\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u300d
\n\u3010\u6a19\u984c\u3011
\nDHA \u306b\u3088\u308b\u8a8d\u77e5\u6a5f\u80fd\u306b\u95a2\u3059\u308b\u7814\u7a76\u30ec\u30d3\u30e5\u30fc
\n\u3010\u76ee\u7684\u3011
\n\u8ab0\u306b P) \uff1a\u75be\u75c5\u306b\u7f79\u60a3\u3057\u3066\u3044\u306a\u3044\u6210\u4eba\u306b
\n\u4f55\u3092\u3059\u308b\u3068 I) \uff1aDHA \u3092\u6442\u53d6\u3055\u305b\u308b\u3053\u3068\u306f
\n\u4f55\u3068\u6bd4\u8f03\u3057\u3066 C) \uff1a\u30d7\u30e9\u30bb\u30dc\u6442\u53d6\u3001\u3082\u3057\u304f\u306fDHA \u6442\u53d6\u306a\u3057\u3068\u6bd4\u8f03\u3057\u3066
\n\u3069\u3046\u306a\u308b\u304b O) \uff1a\u8a8d\u77e5\u6a5f\u80fd\u306b\u5bfe\u3059\u308b\u52b9\u679c\u304c\u8a8d\u3081\u3089\u308c\u308b\u304b
\n\u7814\u7a76\u30c7\u30b6\u30a4\u30f3 S)\uff1a\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\uff08RCT\uff09
\n\u3010\u80cc\u666f\u3011
\n\u8a8d\u77e5\u6a5f\u80fd\u306b\u5bfe\u3059\u308b DHA \u306e\u52b9\u679c\u306b\u3064\u3044\u3066\u306f\u3001\u6570\u591a\u304f\u306e\u5831\u544a\u304c\u3042\u308b\u3002\u3057\u304b\u3057\u3001\u75be\u75c5\u306b\u7f79\u60a3\u3057\u3066\u3044\u306a\u3044\u6210\u4eba\u306b\u7740\u76ee\u3057\u3066\u7814\u7a76\u6210\u679c\u5168\u4f53\u3092\u307e\u3068\u3081\u305f\u30ec\u30d3\u30e5\u30fc\u306f\u9650\u3089\u308c\u3066\u3044\u308b\u3002
\n\u305d\u3053\u3067\u3001\u3053\u308c\u307e\u3067\u306e\u56fd\u5185\u5916\u306e\u77e5\u898b\u3092\u7cbe\u67fb\u3057\u3001\u6a19\u984c\u306e\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\u3092\u884c\u3063\u305f\u3002
\n\u3010\u30ec\u30d3\u30e5\u30fc\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u306e\u7279\u6027\u3011
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